Uses of the drug Condova

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Condova is a brand name drug belonging to the group of anti-cancer drugs with the main ingredient being Hydroxycarbamide, which acts on the immune system to treat melanoma, chronic myeloid leukemia, metastatic or recurrent cancer. , anemia due to blood disorders,... The drug is prescribed by prescription, so when using it, be very careful about the dosage.

1. What is Condova?


Condova brand-name drug is a cancer treatment drug such as leukemia, recurrent cancer, metastatic cancer, melanoma, ... manufactured by SPM Joint Stock Company - VIETNAM. The main ingredients in Condova pills include:
Hydroxycarbamide 500mg. Excipients just enough in 1 capsule: Microcrystalline cellulose, croscarmellose sodium, magnesium stearate, purified water. Packaging is a box of 3 blisters x 10 hard capsules and the drug is sold with a doctor's prescription.

2. What are the uses of Condova?


Condova is a brand name drug that has all the pharmacodynamic properties of the active ingredient Hydroxycarbamide. The active ingredient Hydroxycarbamide is synthesized from urea, which has a therapeutic effect on cancer by inhibiting the synthesis and formation of DNA of cancer cells but does not affect RNA and Protein. In addition, Hydroxycarbamide also helps inhibit the enzyme ribonucleoside diphosphate reductase, thereby helping the body prevent ribonucleotides from converting into deoxyribonucleotides. Therefore, the drug Condova not only reduces the ability of cancer cells to synthesize DNA, but also prevents the metabolism of cancer cells with each other, thereby minimizing the growth and multiplication of cancer cells. letters.
Condova has the ability to reduce the number of sickle cells. In particular, the active ingredient Hydroxycarbamide also works to reduce pain caused by disease and reduce the need for blood transfusion in patients with anemia or leukemia. However, the drug is not able to replace medicine, so it cannot be used for treatment when the disease is progressing rapidly, but only for prevention.
In addition, Condova also has the effect of inhibiting bone marrow, reducing the ability to produce red blood cells and platelets, so it can also be used for cases of unexplained erythrocytosis.

3. How to use Condova


Condova is a brand-name drug that is prepared in the form of a hard capsule, so it is best to take it directly after eating. Medicines are sold by prescription and used as prescribed by the treating doctor.
3.1 Indications Condova brand-name drug is indicated in the treatment of diseases:
Melanoma; Chronic myeloid leukemia ; Cancer recurrence or metastasis; Inoperable ovarian carcinoma; Epithelial cell carcinoma; 3.2 Contraindications Condova is contraindicated in some cases such as:
Do not use for people who are hypersensitive to any of the ingredients in the drug. Do not use the drug in patients with bone marrow failure or severe anemia. Not recommended for use by pregnant or lactating women.

4. Dosage of Condova


Medicines are sold with a doctor's prescription and depending on the age, stage of the disease and the nature of the disease, the doctor will prescribe the appropriate dose.
Hard tumors: Oral 80mg/kg/3day (intermittent or combined therapy) and 20-30mg/kg/day (continuous therapy). Chronic myeloid leukemia: 20-30mg/kg/day. Renal failure: Based on the results of creatinine clearance: Creatinine over 60ml/min, take 20 - 30mg/kg body weight/day; Creatinine less than 60, orally 7.5 - 10 mg/kg body weight/day.

5. Notes before using Condova


Before using Condova, please carefully review the ingredients and expiry date printed on the package. Caution should be exercised in patients undergoing radiation therapy for cancer or those with weakened immune system or severe liver and kidney disease. Do not use the medicine that has been peeled off from the aluminum blister or has expired signs of water, oxidation, mold, etc. Do not arbitrarily use, increase or decrease the dosage or stop using it without consulting a doctor. determined. The drug can be harmful to the nerves, liver and kidneys of the fetus and young child, so it should not be used by pregnant and breastfeeding women. Condova can cause drowsiness, affect the nervous system, so do not use the drug while driving, or operating.

6. Side effects of the drug Condova


This is a brand-name drug, so there may be some accompanying side effects such as:
Itching, rash Fever accompanied by chills On the skin appear bruises, dermatitis, red skin or unusual bleeding. Hallucinations, convulsions, drowsiness Anemia, decreased white blood cells, platelets Increased uric acid in the blood Hair loss, skin peeling, .. (rare)

7. Drug interactions


When used together with other drugs, it may reduce the effectiveness of the drug or increase the toxicity of the drug. Therefore, in treatment, it is not recommended to use Condova with some of the following drugs:
Bone marrow suppressants: cause myelosuppression Clozapine: may cause bone marrow toxicity Probenecid: reduce the effectiveness of probenecid Vaccines increase the risk of vaccines

8. How to handle missed dose and overdose


In the process of using drugs, overdose and missed doses are inevitable. When taking an overdose, stop using the drug, try to induce vomiting and drink lots of water, then immediately contact your doctor or the nearest medical facility for timely treatment. Conversely, if you miss a dose, you can take it as soon as you remember, but if it's close to the time of your next dose, skip the missed dose and take the next dose as directed. Absolutely do not take supplements by increasing the dose of the next dose. Condova is a brand name drug belonging to the group of anti-cancer drugs with the main ingredient being Hydroxycarbamide, which acts on the immune system to treat melanoma, chronic myeloid leukemia, metastatic or recurrent cancer. anemia due to blood disorders,... The drug is prescribed by prescription, so when using it, be very careful about the dosage.
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