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Tamerlane 5 is a drug for quick treatment of respiratory allergies, acute alcohol delirium or skin allergies,... During the use of the drug, patients should strictly follow the doctor's recommendations on dosage. , frequency and duration of drug administration to ensure early effective treatment.1. What is Tamerlane 5?
Tamerlane 5 belongs to the antiallergic group and is used for cases of respiratory allergies. Tamerlane 5 is prepared in the form of film-coated tablets, packed in boxes of 3 blisters, 6 blisters or 10 blisters. Currently, Tamerlane 5 is produced by Dong Nam Pharmaceutical Manufacturing - Trading Joint Stock Company and is widely circulated nationwide.Each Tamerlane 5 tablet contains the following active ingredients:
Main active ingredient: Alimemazine tartrate 5mg. Other excipients: Wheat starch PVP, Lactose, Hypropyl - Methyice, Magnesium stearate, Titanium dioxide, Talc powder, Color erythrosin and Polyethylene glycol. The main active ingredient Alimemazine has antihistaminic and sedative effects similar to clopromazine. In addition, Alimemazine also has the effect of calming, regulating the autonomic nervous system and anti-cholinergic very well. This active ingredient can also dilate blood vessels, and at the same time increase the vascular permeability of histamine on the capillaries, thereby reducing or reducing allergic reactions, inflammation, edema and itching.
The same study shows that the active ingredient Alimemazine in Tamerlane 5 also improves spasms in the digestive tract, helping to reduce abdominal pain caused by allergies. Furthermore, Alimemazine strongly promotes the vasoconstrictor effect of histamine, inhibiting the secretion of tears and saliva related to histamine.
Patients can take Tamerlane 5 as a CNS depressant that provides sedation and reduces alertness. In addition, the drug also helps fight vomiting and motion sickness effectively thanks to its anticholinergic ability.
2. Indications - Contraindications of Tamerlane 5
2.1. Indications for use of Tamerlane 5
Currently, Tamerlane 5 is commonly used to treat the following cases: Currently, Tamerlane 5 is commonly used to treat the following cases:
Treatment of acute delirium in patients with alcohol withdrawal alcohol. A dry cough, including a cough caused by irritation or allergies. Respiratory allergies, such as sneezing, runny nose, rhinitis. Skin allergies such as hives or rashes. Treatment of frequent regurgitation in children. Treatment of insomnia in children and adults.
2.2. Contraindications to the use of Tamerlane 5
Do not use Tamerlane 5 in the following cases without consulting your doctor:The patient is allergic or has a hypersensitivity reaction to the active ingredient Alimemazine or any other excipients in the drug. . People with liver or kidney dysfunction, Parkinson's disease, epilepsy, pheochromocytoma, hypothyroidism, myasthenia gravis or an enlarged prostate gland. Patients who are sensitive to Phenothiazines or have ever had narrow-angle glaucoma. Patients who have overdosed on Opioids, Barbiturics or alcohol. Patients with leukopenia or a history of agranulocytosis. Children under 2 years of age are not recommended to use Tamerlane 5.
3. Dosage and instructions for use of Tamerlane 5
3.1. The average recommended dose of Tamerlane 5
Dosage of Tamerlane 5 drug will be determined specifically based on the health status of each patient:Treatment of itchy papules and urticaria: Adults: Use 10mg × 2-3 times/day, even Doses of up to 100 mg/day may be used if persistent pruritus and urticaria are difficult to treat. Elderly: The dose can be reduced by 10mg × 1-2 times/day. Children 2 years of age and older: Dosage 2.5 - 5mg × 3 - 4 times/day. Dosage of Tamerlane 5 used before anesthesia: Children from 2 to 7 years old: Use a maximum dose of 2mg/kg body weight about 1-2 hours before anesthesia. Dosage of Tamerlane 5 used for anti-histamine and antitussive: Adults: Use dose from 5-40mg/day, divided into equal doses. Children: Use dose from 0.5 to 1mg/kg body weight/day, divided into equal doses. Dosage of Tamerlane 5 used to induce sleep: Adults: Take 5 - 20mg before going to bed. Children: Use from 0.25 - 0.5mg/kg body weight/day before going to bed. Dosage of Tamerlane 5 to treat acute alcohol delirium: Adults take a dose of 50-200mg/day.
3.2. Instructions for using Tamerlane 5 correctly
Tamerlane 5 is formulated as a film-coated tablet, so it should be taken orally at the dose recommended by your doctor. When taking orally, the patient should swallow the tablet whole, avoiding crushing or chewing. In addition, Tamerlane 5 should not be taken with water other than water, such as carbonated soft drinks, alcoholic beverages or caffeine.Before treatment with Tamerlane 5, you need to carefully read the instructions for use listed in the information leaflet attached to the medicine box. Absolutely do not arbitrarily apply, adjust the dose of the drug or stop using it without discussing specifically with your doctor.
3.3. How to treat an overdose of Tamerlane 5
When taking an overdose of Tamerlane 5 and experiencing severe CNS depression symptoms, the patient needs immediate respiratory support. In certain cases, a severe dystonia reaction may occur, then the doctor will give the patient an intramuscular or intravenous injection of Procyclidin from 5 to 10 mg or Orphenadrine from 20 to 40 mg.For patients taking an overdose of Tamerlane 5 and experiencing convulsions will be managed by intravenous injection of Diazepam. If sedation-induced malignant syndrome occurs, the physician will conduct treatment by keeping the patient cool and administering Dantrolen sodium.
4. What side effects can Tamerlane 5 cause?
In general, the side effects that Tamerlane 5 causes will depend on the dose and duration of drug use by the patient, specifically:Common side effects: Drowsiness, fatigue, headache, dryness mouth, mild dizziness or thick phlegm. Uncommon side effects: Eye disorders, urinary retention or constipation. Rare side effects: Leukopenia, hypotension, agranulocytosis, increased heart rate, hepatitis, cholestatic jaundice, Parkinson's tremor, extrapyramidal symptoms, acute dystonia, mink, tardive dyskinesia, reduced seizure threshold in epilepsy, dry mouth damaging to enamel and teeth, risk of respiratory arrest, sudden death in young children. You should tell your doctor right away if you experience any of these side effects while you are taking Tamerlane 5. Some reactions may go away after you stop taking the medicine, but some symptoms may occur. the risk of serious progression and threat to the patient's health when detected late.
5. Notes and cautions when using Tamerlane 5
5.1. What precautions should be taken while using Tamerlane 5
Here are some things that patients need to keep in mind and caution during treatment with Tamerlane 5:Be careful when administering Tamerlane 5 to elderly patients, especially when the weather is very cold or very hot ( risk of hypothermia or hyperthermia). If drowsiness occurs during the first few days of treatment with Tamerlane 5, patients should inform their doctor as soon as possible to receive helpful advice. Elderly people taking Tamerlane 5 are prone to orthostatic hypotension. Alimemazine active ingredient in the drug has a risk of adversely affecting skin tests and allergens. Do not use alcohol or other CNS depressants during treatment with Tamerlane 5. It has been reported that there is an increased risk of jaundice and extrapyramidal symptoms in the neonate when the mother is taking Tamerlane. 5 during pregnancy. If it is necessary to use the drug, pregnant women should consult a doctor carefully. Alimemazine can be excreted in breast milk, so this drug should not be used in nursing women, or forced to stop breastfeeding during treatment. It is not recommended to use Tamerlane 5 while driving or operating machinery because the drug has a drowsy effect. Tamerlane 5 has a shelf life of 36 months from the date of manufacture, you need to check the expiration date carefully to avoid taking the medicine past the expiration date. Store the medicine in a cool dry place, away from direct light and high humidity.
5.2. Does Tamerlane 5 interact with other drugs?
Some drugs have a potential for interactions when used with Tamerlane 5, including:Increased CNS depression and respiratory depression when Tamerlane 5 is combined with barbituric hypnotics, alcohol and a sedative. other sedatives. Affects the antihypertensive effect of antihypertensive drugs, especially alpha-adrenergic receptor blockers. Increases anti-cholinergic effect of Tamerlane 5 drug when used together with other anti-cholinergic drugs, easily causing heatstroke and constipation,... Tamerlane 5 drug antagonizes the therapeutic effect of Levodopa, Amphetamine, Guanethidine, Adrenalin or Clonidine ,... Some other drugs such as Lithium, Parkinson's medicine or antacids.
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