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Spasmaboston is a smooth muscle antispasmodic drug with the main active ingredient being Alverine. Spasmaboston is used in the treatment of pain caused by spasms of smooth muscle of the gastrointestinal, urinary, and genitourinary tracts. The following article provides you with information about the uses and notes when using Spasmaboston.
1. What is Spasmaboston?
Spasmaboston has a papaverin-type antispasmodic effect. Spasmaboston has a direct effect on uterine and gastrointestinal smooth muscle. Recently, the effect of Alverine on the gastrointestinal tract has been identified by three mechanisms: decreased intestinal sensitivity, calcium channel blocker and serotonin 5HT1A receptor inhibition.
Spasmaboston has no atropine-like effect, so it can be used in cases of prostate enlargement or glaucoma.
After Spasmaboston is absorbed from the gastrointestinal tract, the drug is rapidly metabolized to an active metabolite. Peak plasma concentrations are reached 1 to 1.5 hours after dosing. After that, the drug will be converted to inactive substances and excreted in the urine.
2. Indications and contraindications of Spasmaboston
Spasmaboston is indicated for use in the following cases:
Symptomatic treatment of pain caused by spasms of smooth muscle in the gastrointestinal tract due to dysfunction of the gastrointestinal tract and biliary tract. Symptomatic treatment of pain caused by spasms of the urogenital region (dysmenorrhea, postpartum pain, renal colic and urinary tract pain). Spasmaboston is contraindicated for use in the following cases:
Hypersensitivity to Spasmaboston or any other ingredient in the drug. Women who are breastfeeding. Intestinal obstruction or paralytic ileus. Intestinal obstruction due to feces. Loss of colon tone.
3. How to use Spasmaboston
Spasmaboston tablets are taken orally.
In adults: dose 1-3 tablets / time x 3 times / day.
Do not use Spasmaboston for children under 12 years old.
Overdosage of Spasmaboston may cause hypotension and symptoms of toxicity similar to atropine.
Treatment: similar to the case of Atropin poisoning. Perform gastric lavage for the patient, and should give activated charcoal before proceeding. In addition, supportive measures should be taken to treat hypotension. In case of overdose of Spasmaboston, immediately go to the nearest medical facility for timely treatment.
If you forget to take a dose of Spasmaboston, take it as soon as possible. If it is almost time for the next dose of Spasmaboston, skip the missed dose and take the next dose as scheduled. Also, do not double the dose of Spasmaboston.
4. Undesirable effects when using Spasmaboston drugs
Side effects when using Spasmaboston are usually mild and do not need to be treated. Possible symptoms such as nausea, headache, dizziness, itching, rash, allergic reactions including anaphylaxis have been reported.
In case of itching, rash, spasmaboston should be discontinued and anaphylactic reactions monitored, although this is very rare.
5. Notes when using Spasmaboston
Consult your doctor if new symptoms appear or symptoms persist, worsen or do not improve after 2 days of treatment. Pregnancy: Due to limited evidence on the safety of Spasmaboston during pregnancy in preclinical studies, Spasmaboston should not be used in this population. Lactation: Spasmaboston should not be used during lactation due to limited data on the safety of Alverine in this population. Spasmaboston is used in the treatment of pain caused by spasms of smooth muscles of the gastrointestinal tract, urinary tract, and genitals. The safety and effectiveness of Spasmaboston when used in pregnant and lactating women is limited, so its use should be avoided in these subjects. Before taking Spasmaboston, you should consult with your doctor for safe and effective use of the drug.
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