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Sozfax 4 is an anti-inflammatory, analgesic, used in the treatment of pain in arthritis, rheumatoid arthritis, gouty arthritis. Sozfax 4 is used orally with the main ingredient being Lornoxicam. Dosage, how to use Sozfax 4 and side effects of the drug will be in the article below.
1. What is Sozfax 4?
Sozfax 4 is classified as an anti-inflammatory and pain reliever. As one of the non-steroidal anti-inflammatory drugs used in the treatment of pain in arthritis, rheumatoid arthritis, gouty arthritis.
As for the main active ingredient, Sozfax 4 contains 4mg of Lornoxicam, a new non-steroidal anti-inflammatory agent belonging to the oxicam group that partially inhibits Prostaglandin synthesis (inhibits cyclooxygenase enzyme).
2. Uses of Sozfax 4
Sozfax 4 drug with the main active ingredient is Lornoxicam is often used in the treatment of osteoarthritis pain after surgery, joint pain due to rheumatoid arthritis, arthritis caused by gout.
3. Indications for taking Sozfax 4
In the following cases of joint pain and arthritis, Sozfax 4 is indicated for patients
Pain due to rheumatoid arthritis. Low back pain, ankylosing spondylitis, gouty arthritis.
4. Contraindications to the use of Sozfax 4
As a non-steroidal anti-inflammatory drug, Sozfax 4 also causes unwanted side effects in patients, so it should be contraindicated in the following cases:
Patients with a history of hypersensitivity to any of the ingredients of the drug (composition stated on the instruction manual). Patients with a history of hypersensitivity to other non-steroidal anti-inflammatory drugs (including acetyl salicylic acid). The patient has had gastrointestinal bleeding and cerebral hemorrhage before. The patient has coagulation and bleeding disorders. The patient is suffering from peptic ulcer, acute gastritis, history of recurrent peptic ulcer. Patients with severe hepatic/renal dysfunction (serum creatinine > 700 micromol/L). People with thrombocytopenia, elderly patients and weighing less than 50kg. The patient needs urgent surgery. Patients with severe or uncontrolled heart failure. Contraindications to use Sozfax 4 in pregnant / lactating women, children under 18 years old
5. Dosage & how to use Sozfax 4
Sozfax 4 is used orally, the patient takes it with 1 glass of cooled boiled water.
Mild - moderate pain: 8-16mg/day, divided into 2 to 3 times. The maximum dose should not exceed 16mg/day, equivalent to 4 Sozfax 4 tablets. Dosage in osteoarthritis, rheumatoid arthritis: Start with 12mg/day divided into 2-3 oral doses, then maintain with 16mg/day. divided into 2-3 times a day. In patients with hepatic impairment, the maximum dose is 12 mg/day in divided doses. Adherence to the dose of Sozfax 4 is very important, because taking the wrong dose can lead to reduced absorption, decreased bioavailability and potentially serious side effects.
6. Sozfax 4 . side effects
6.1. Common and rare side effects of the drug Sozfax 4 Patients taking Sozfax 4 may experience headaches, dizziness, loss of appetite, sweating and body weakness Insomnia is a common symptom, symptoms More serious symptoms are depression In the digestive system, Sozfax 4 can cause side effects such as difficulty swallowing, constipation, gastritis, gastroesophageal reflux, stomach ulcers, hemorrhoids, rectal bleeding, increased liver enzymes. In the hematopoietic system, Sozfax 4 causes anemia, hematoma, increased bleeding time due to thrombocytopenia. Skin signs show that patients experience side effects of Sozfax 4 are dermatitis, itching, hair loss. 6.2. Drug Interactions Sozfax 4 When using Sozfax 4, it should be noted that interactions with foods and drug groups below
Sozfax 4 are reduced bioavailability and absorption when taking the drug with meals. Therefore, it is not recommended to take with meals. Drugs that interact with Cimetidine, Warfarin, Phenprocoumon, Heparin, Sulphonylure, Corticosteroids, Lithium, diuretics, beta-channel blockers, Angiotensin II receptor antagonists, selective Serotonin inhibitors, Lithium, Methotrexate, Digoxin, Quinolone , Cyclosporin , Tacrolimus , Pemetrexed .
7. Notes when using Sozfax 4
In the following subjects should be cautious when using Sozfax 4
People with mild and moderate renal failure. If Sozfax 4 is used with caution in the above subjects with signs of decline in renal function, the drug should be discontinued. Renal function is a function that should be closely monitored in Sozfax 4 users with prior surgery or heart failure. For patients taking Sozfax for more than 3 months, blood (hemoglobin), creatinine, and liver function tests should be performed. If using Sozfax 4 to treat and experience gastric bleeding, gastric ulcer or gastric perforation, the drug must be stopped immediately because these factors can endanger the patient's life. Patients with diabetes, high blood pressure when using Sozfax 4 also need to be closely monitored. Sozfax 4 can cause dizziness and drowsiness, so it is not recommended to drive or operate machinery. In pregnant women, Sozfax 4 is not recommended because it can cause fetal toxicity and affect childbirth (increase bleeding time, inhibit uterine contractions cause prolongation of labor time. ). In women who are breastfeeding, Sozfax 4 is also not recommended for this population. Sozfax 4 is a non-steroidal anti-inflammatory drug, specialized in the treatment of pain caused by osteoarthritis and rheumatoid arthritis. Sozfax 4 is a drug prescribed by a doctor, patients are not allowed to use it on their own.
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