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Savi Esomeprazole 40 contains the active ingredient Esomeprazole, which is used to treat gastroesophageal ulcers caused by reflux. Dosage is different for each person depending on the health condition and the severity of the disease.1. What is Savi esomeprazole 40?
Savi Esomeprazole 40 belongs to the group of gastrointestinal drugs, with the main ingredient being Esomeprazole 40mg. This active ingredient works to reduce gastric acid secretion by inhibiting the proton pump in gastric parietal cells.The drug is in the form of enteric-coated film-coated tablets.
Uses of Savi esomeprazole 40 in the treatment of the following conditions:
Gastroesophageal reflux in adults and children from 12 years of age and older; Esophageal ulcer due to reflux; Zollinger Ellison syndrome. In addition, the drug is also used for long-term treatment to prevent stomach bleeding caused by ulcers.
2. Usage and dosage of Savi esomeprazole 40
Savi Esomeprazole 40 is taken orally, swallow 1 tablet whole (can be taken with water), do not break or chew. It is best to take the medicine at least 1 hour before eating to be effective. Dosage of Savi Esomeprazole 40 depends on the purpose of treatment as follows:Treatment of esophageal ulcers caused by reflux: 1 tablet / time / day, used for 4 - 8 weeks and can be extended for another 4 - 8 weeks if not cured or endoscopy still shows signs of inflammation. For children over 12 years old, the duration of treatment is 4 weeks, but if after 4 weeks it is not cured, it can be used for another 4 weeks; Treatment of Zollinger-Ellison syndrome: 1 tablet/time, 2 times/day. Depending on the response of the patient to adjust the dose if there are clinical manifestations. The maximum dose can be up to 2 tablets, 2 times/day (equivalent to 160mg/day); Prophylaxis of recurrence of gastric and duodenal ulcers: 1 tablet of Savi Esomeprazole 40 / time / day; Hepatic impairment: Do not reduce the dose if the patient has mild and moderate hepatic impairment. However, in people with severe liver failure, the maximum dose is 20mg/time/day; Elderly, renal failure: No need to reduce the dose. Savi Esomeprazole 40 can be taken at a dose of 80mg and still be safe, but a dose of 200mg can cause abdominal pain, fatigue, irritability, and nausea. At that time, the patient should be taken to a medical facility for timely treatment, symptomatic treatment and recovery, because Esomeprazole does not have a specific antidote.
3. Side effects of Savi Esomeprazole 40
Savi Esomeprazole 40 may cause some unwanted side effects with the following frequency:Common: Headache, abdominal pain, nausea, vomiting, flatulence, diarrhea, constipation; Uncommon: Peripheral edema, dry mouth, pruritus, urticaria, dermatitis, dizziness, vertigo, fracture (wrist bone, hip bone); Rare: Increased liver enzymes, hypersensitivity reactions, anaphylaxis, blurred vision, bronchospasm, agitation, depression, irritability, sweating, myalgia, alopecia, skin photosensitivity , taste disturbances , stomatitis , fungal infections in the gastrointestinal tract , blood sodium / platelets and white blood cells decreased . Very rare: Savi Esomeprazole 40 very rarely causes liver failure, hepatic encephalopathy, interstitial nephritis, muscle weakness, toxic skin necrosis, Stevens-Johnson syndrome, erythema, hallucinations, agitation, decreased platelet count, agranulocytosis, hallucinations, gynecomastia in men. If you see any of the above symptoms, the patient should immediately contact a pharmacist, doctor or go to a medical facility for advice and guidance.
4. Some notes when using Savi Esomeprazole 40
Some notes to pay attention to when using Savi Esomeprazole 40 include:Savi Esomeprazole 40 should not be used for people with hypersensitivity to the ingredients of the drug or patients who are taking Nelfinavir. People with liver failure, pregnant or lactating women should use caution; If you want to use Savi Esomeprazole 40, it is necessary to exclude the possibility of malignancy in the stomach; Savi Esomeprazole 40 used for a long time can cause stomach atrophy, hypomagnesemia and cause manifestations such as fatigue, dizziness, convulsions, spasticity, and delirium. However, after taking magnesium supplements, the symptoms improved. Therefore, blood magnesium levels should be checked before taking Savi Esomeprazole 40 and must be monitored during treatment; Use of proton pump inhibitors increases the risk of mild gastrointestinal infections; Absorption of vitamin B12 may be reduced when taking Savi Esomeprazole 40 because the active ingredient Esomeprazole reduces gastric acid secretion; Proton pump inhibitors, when used in high doses for a long time (more than 1 year) may increase the risk of mild fractures, especially in the elderly; Before or after treatment with Savi Esomeprazole 40, the risk of interactions with drugs that metabolize CYP2C19 should be assessed; In patients with lupus erythematosus, if detecting lesions on the skin after exposure to the sun, accompanied by joint pain, the patient should be taken to a medical facility for treatment and consideration of discontinuation of the drug; People with glucose-galactose malabsorption or Lapp lactase deficiency should not take the drug; Savi Esomeprazole 40 may interact with Protease Inhibitors, Atazanavir and Nelfinavir, Proton Pump Inhibitors, Tacrolimus, Antifungals, Cardiac Drugs, Drugs whose absorption is dependent on gastric pH, Antidepressants, Europe, antibiotics Clarithromycin, Amoxicillin, PPIs and Warfarin, CYP3A4 inhibitors. Therefore, it is necessary to inform the doctor about the medicines you are taking, including prescription and non-prescription, herbs, and dietary supplements. The use of Savi Esomeprazole 40 is to reduce gastric acid secretion for the treatment of gastroesophageal reflux disease in adults and children 12 years of age and older, reflux esophagitis and Zollinger Ellison syndrome. In addition, the drug is also used to prevent recurrent gastric bleeding due to ulcers. To ensure the safety of health, patients need to take the medicine exactly as prescribed by the doctor.
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