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Clopidogrel 75mg Ridlor is indicated for the prevention of blood clots in patients with myocardial infarction, stroke or established peripheral arterial disease. So what does Ridlor do, let's find out through the following article.1. What is Ridlor 75mg?
The drug Ridlor 75mg has the main active ingredient Clopidogrel and other excipients in a sufficient amount. Ridlor 75mg drug is effective in the treatment of:Primary prevention of disorders caused by thromboembolism such as myocardial infarction, stroke and peripheral artery disease. Control and secondary prevention in atherosclerotic patients with recent stroke, recent myocardial infarction, or established peripheral artery disease
2. Usage and dosage of Ridlor 75mg
2.1. How to use the drug?
Ridlor 75mg is to be taken orally with or without food.2.2. Therapeutic dose of the drug
Clopidogrel can be taken with or without food. For people with a history of atherosclerosis: The therapeutic dose is 1 tablet (75mg) per day. The prophylactic dose to prevent thromboembolic disorders such as myocardial infarction, peripheral artery disease and stroke is: 1 tablet (75mg)/day. Acute coronary syndromes (unstable angina or non-Q-wave myocardial infarction): Initial dose is 300 mg as a single dose and maintenance dose is 75 mg daily. Patients with renal impairment and the elderly: No dosage adjustment necessary Children and adolescents: The safety and effectiveness of Ridlor 75mg in children and adolescents have not been established. Note: The above therapeutic dose is for reference only. The specific treatment dose depends on the condition and the progress of the disease of each person. To get the right dose for your health and physical condition, you need to consult your doctor or medical professional.2.3. In case of over/missing dose
In case of overdose: Overdose due to the use of Ridlor 75mg can lead to prolonged bleeding time and subsequent bleeding complications. You should note that if you observe bleeding, you should immediately notify the treating doctor for a reasonable treatment method. Currently, there is no antidote to the pharmacological activity of clopidogrel. If intervention is needed for prolongation of bleeding time, platelet transfusion may reverse the effects of clopidogrel. In the event of an emergency, immediately call 911 or go to the nearest medical facility. In case of missed dose: You need to take the next dose as soon as you remember. However, if it is too short to take the missed dose with the next dose, skip the missed dose and continue with the dosing schedule. Never use a double dose to make up for a missed dose.3. Undesirable effects of the drug Ridlor 75mg
Clopidogrel is generally well tolerated. However, there are also some undesirable effects when using it. Common Adverse Reactions: Gastrointestinal disorders (diarrhea, abdominal pain, dyspepsia and nausea) and skin allergies (erythema, pruritus). Less common side effects: Chest tightness, nosebleeds. Rare adverse effects: Gastric ulcer, gastrointestinal bleeding, severe neutropenia or agranulocytosis, thrombocytopenic purpura, thrombocytopenia, aplastic anemia fertility, kidney disease such as nephritic syndrome, loss of taste, acute arthritis. Other side effects: Intracerebral hemorrhage, thrombocytopenia, ocular haemorrhage.4. Interactions of Ridlor 75mg
Aspirin: A pharmacodynamic interaction between Clopidogrel and Aspirin may occur, leading to an increased risk of bleeding. Therefore, caution should be exercised when these two drugs are combined. However, Ridlor 75mg and Aspirin can be combined for up to 1 year. Heparin: A pharmacodynamic interaction between Ridlor 75mg and Heparin may lead to an increased risk of bleeding. Therefore, the use of two drugs simultaneously should be borne in mind. Warfarin: May increase the risk of bleeding, so concomitant use of Ridlor 75mg and Warfarin should be noted. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): In a study in healthy volunteers receiving naproxen, the concomitant use of naproxen and clopidogrel was associated with an increased potential for gastrointestinal bleeding. Therefore, caution should be exercised when using Ridlor 75mg concomitantly with non-steroidal anti-inflammatory drugs. Drugs Metabolized by the Cytochrome P450 System: At high concentrations in vitro, clopidogrel inhibits Cytochrome P450 (2C9). Ridlor 75mg may affect the metabolism of phenytoin, tamoxifen, tolbutamide, warfarin, furosemide, fluvastatin and many other non-steroidal anti-inflammatory agents, but there are no data on the severity of these interactions. Care should be taken when combining Ridlor 75mg with the above drugs. Combination with other treatments: Concomitant use with drugs that inhibit CYP2C19 enzyme activity may decrease concentrations of the active metabolite Clopidogrel.5. Some notes when using Ridlor 75mg
Before using Ridlor 75mg, you need to carefully read the instructions for use and refer to the information below.5.1. Contraindications
Ridlor 75mg is contraindicated in the following cases:Hypersensitivity or local sensitivity to the active ingredients of the drug or any of its components. Pathological bleeding such as peptic ulcer or intracranial hemorrhage. Severe liver failure.
5.2. Using drugs for other special subjects
Use in pregnancy or lactation: Because there is no clinical evidence on exposure to clopidogrel during pregnancy, clopidogrel use during pregnancy is not recommended. Currently, there is no evidence whether clopidogrel is excreted in human milk. Use in driving and using machines: Clopidogrel has no or negligible influence on the ability to drive and use machines. Use caution when using Ridlor 75mg with people with bleeding due to trauma, surgery or other diseases. People preparing for surgery, must stop using Ridlor 75mg 5 days before surgery. Ridlor 75mg should be used with caution in patients with bleeding-prone lesions (such as ulcers). Care should be taken when administering drugs that can cause similar damage to people taking Clopidogrel. Caution should be exercised in subjects with hepatic impairment who have altered metabolism (poor metabolism due to CYP2C19).Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
