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Reclast drug containing zoledronic acid is indicated in the treatment or control, prevention of osteoporosis, hypercalcemia, multiple myeloma, bone metastases, ... However, Reclast can cause some Unwanted side effects such as fatigue, joint pain, fever... Therefore, before using Reclast, patients need to learn carefully the information and follow the instructions of the treating doctor.
1. Mechanism of action of the drug Reclast
Reclast contains zoledronic acid, which works to slow down bone destruction caused by cancer cells. Cancer cells of some tumors such as breast cancer, prostate cancer, lung cancer can metastasize to the bones. Multiple myeloma can then also be viewed as a cancer affecting plasma cells, and these factors are found in the bone marrow and are directly related to bone. In both cases of this effect, the bone cancer cells often cause more bone breakdown or wear than normal. When that happens, the affected bone will become more prone to fracture, causing a lot of pain for the patient, possibly even breaking due to the damage of cancer cells.2. Indications to use Reclast
Reclast is used to treat certain bone disease or Paget's disease that causes abnormal bone loss. The Zoledronic acid in Reclast is also used to treat osteoporosis in men and women after menopause. These compounds are used to prevent osteoporosis even in cases of prolonged use of corticosteroid drugs.
3. Dosage and how to use Reclast
Reclast is injected into a vein at the dose and frequency prescribed by the treating doctor. In addition, doctors may prescribe additional micronutrients such as calcium and vitamin D to promote bone health. If the patient has Paget disease, it is important to pay attention to supplementing with calcium and vitamin D as prescribed during the two weeks after receiving the dose of Reclast. Because vitamin D and calcium play an important role in preventing hypocalcemia.4. Unwanted side effects when using Reclast
Reclast can cause some unwanted side effects and the degree of dependence depends on the specific case.
Nausea and vomiting may occur when using Reclast. You can tell your doctor to prescribe medication to help control this condition, and in addition, the doctor may also prescribe appropriate dietary changes to improve the condition. For example, the patient should avoid using foods that can aggravate symptoms such as using foods that are greasy, fatty or sour... Instead, the patient should take antibiotics. acid, salt water, ginger beer to relieve symptoms of nausea and vomiting. Anemia with a low number of red blood cells in the blood. Red blood cells carry oxygen to the body's tissues. But when the red blood cell count drops, the body can feel tired and weak. In addition, the patient also feels shortness of breath, chest pain... If the red blood cell count is too low, the patient needs a blood transfusion. Muscle and joint pain. Zoledronic acid may cause moderate to severe musculoskeletal pain in patients. This happens about 1 day or a few months after using Reclast. When experiencing these signs, the patient should notify the treating doctor to have a plan to relieve the pain. The patient is always tired. After cancer treatment, patients always feel exhausted and this condition takes a long time to improve. Therefore, patients need to adjust as well as plan for long-term rest and save energy for important activities. In addition, the patient can do exercise to fight fatigue by walking, relaxing... There are also many health problems such as "difficulty breathing, jaw tumor, lower Blood calcium can occur, so users need to be very careful.
Some notes when using Reclast
Before using Reclast, the patient needs to provide a list of previously used drugs including prescription drugs, non-prescription drugs, herbs for the doctor to decide. appropriate treatment. Some products may interact with Reclast such as calcium-containing liquid, mineral supplement liquid... Besides, Reclast medicine may cause kidney damage when used together with aminoglycoside antibiotics, tacrolimus. Before any surgery, including dental procedures, the patient should inform the doctor about the medications used. Then the doctor can stop using Reclast before surgery and for each case, there will be specific instructions. Reclast may make you feel dizzy. Therefore, when performing driving, or machinery or doing anything that requires alertness, you should consider before using. In addition to the above important information, if you have more questions about Reclast, you should consult your doctor for appropriate indications.
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Reference source: oncolink.org
