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What is the effect of Rapeed 20 or what is the use of Rapeed 20 for treatment? Here is all the information about Rapeed 20 that everyone needs to know before taking it to ensure safety and get the best results.
1. What is Rapeed 20?
Rapeed 20 is a pharmaceutical product manufactured by Alkem Laboratories., Ltdn India and imported into our country.
Rapeed 20 is classified as a gastrointestinal drug with the main ingredient being Rabeprazole sodium 20mg content used for the treatment of peptic ulcer, reflux esophagitis and some other diseases in the gastrointestinal tract. chemical.
The drug is prepared in the form of enteric coated tablets and is packaged in boxes of 3 blisters x 10 tablets.
2. Uses of Rapeed 20mg
2.1 What does Rapeed 20mg do? Rabeprazole ingredient in Rapeed 20mg drug has 2 main effects:
Inhibition of gastric acid secretion: In rabbits, it was shown that Rabeprazole sodium component inhibits gastric acid secretion stimulated by dibutyl cyclic AMP in gastric gland.
Experiments in dogs have shown that rabeprazole sodium strongly inhibits gastric acid secretion stimulated by histamine or pentagastrin. Rabeprazole sodium inhibits gastric acid secretion under normal or histamine-stimulated conditions experimentally in rats.
Reversal of the antisecretory activity of Rabeprazole sodium is faster and the increase in blood gastrin levels is lower with Rabeprazole sodium than with other proton pump inhibitors.
Anti-ulcer activity: Experiments in rats showed that rabeprazole sodium has a strong anti-ulcer effect on various types of ulcers and improves gastric mucosal wounds.
2.2 Indications for drugs: With the above use of Rabeprazol ingredients, Rapeed 20mg drug is used to appoint in the following cases:
Treatment of gastric and duodenal ulcers. Mouth ulcers. Reflux esophagitis. Zollinger-Ellison syndrome. 2.3 Contraindications Raped 20mg drug is contraindicated in case of hypersensitivity to the component Rabeprazole or to its derivative Bezimidazol or to any of the ingredients in the drug.
3. Usage – Dosage
Rapeed 20 drug will promote its full therapeutic effect if the patient uses it properly and in sufficient dosage as prescribed by a professional doctor. Here are the ways to use and the reference dosage of the drug:
How to use:
The drug is in the form of enteric coated tablets, so the tablet should be swallowed whole. Absolutely do not chew, crush, break or disperse the medicine when using.
The drug can be taken with or without food to help the drug Rapeed 20 be promoted.
Dosage:
The dose of the drug depends on each purpose and progress of the disease, the patient's condition, which will have a specific dose adjustment. Reference dosage for adults in some diseases is as follows:
Gastroesophageal reflux disease (GERD): Take 1 tablet once a day x 4-8 weeks, can be used for an additional 8 weeks as needed. Duodenal ulcer: Take 1 tablet / day / time x 4 weeks. Zollinger-Ellison syndrome: Initial dose is 3 tablets/time/day and can be adjusted according to response. Healing of ulcerative or erosive gastroesophageal reflux disease (GERD): The recommended oral dose is 20 mg rabeprazole once daily for 4-8 weeks. For patients who do not heal after 8 weeks of treatment, an additional course of 8 weeks can be used. Maintenance after healing of ulcerative or erosive gastroesophageal reflux disease (GERD): 20 mg rabeprazole once daily. Treatment of symptomatic gastroesophageal reflux disease (GERD): The recommended oral dose is 20 mg once daily for 4 weeks. If there is no improvement after 4 weeks, another course of treatment can be used. Healing of duodenal ulcer: The recommended oral dose is 20mg of rabeprazole once a day after breakfast for 4 weeks. If the ulcer does not heal, another course of treatment may be needed.
4. Side effects
Side effects reported with the use of Rapeed 20mg include: Asthenia, allergic reactions, fever, chills, fatigue, stiff neck, photosensitivity, digestive disturbances, belching, dryness. mouth, rectal bleeding, black stools, anorexia, stomatitis, gingivitis, glossitis, gallstones, cholecystitis, esophagitis, colitis, pancreatitis.
When experiencing side effects of the drug or other unusual manifestations, immediately notify the treating doctor, pharmacist or go to a medical facility for advice, examination and timely treatment.
5. Drug interactions
Studies in healthy patients have shown that rabeprazole has no significant interactions with drugs metabolised by CYP450. There have been high reports of increases in coagulation index and prothrombin time in patients receiving concomitant proton pump inhibitors (PPIs), including rabeprazole with warfarin. Concomitant treatment of rabeprazole with ketoconazole in healthy subjects reduces the effect of ketoconazole. Concomitant use of PPIs with atazanavir can significantly reduce plasma concentrations of atazanavir. Concomitant use of rabeprazole with amoxicillin and clarithromycin increases the serum concentration of rabeprazole. Concomitant use of PPIs and methotrexate increases and prolongs plasma concentrations of methotrexate or its metabolite hydroxymethotrexate To avoid drug interactions that affect the effectiveness of Rapeed 20mg and other drugs being used, the patient should inform the doctor. treating doctor about all medications being taken for appropriate advice and prescription.
6. Notes and cautions
To use the drug Rapeed 20 to ensure safety and achieve the best therapeutic effect, patients should note and be cautious:
Use the drug as prescribed and guided by a specialist doctor or pharmacist and manufacturer. export. Absolutely do not arbitrarily increase or decrease the dose, stop suddenly, stop the treatment course without the doctor's prescription. Acute interstitial nephritis has been reported in patients treated with rabeprazole and should therefore be discontinued if acute interstitial nephritis occurs. The drug is not for use in patients under 12 years of age. Use with caution in pregnant or lactating women, use only when absolutely necessary and prescribed by a qualified doctor, assess the benefits and risks before use. No effect of the drug on the ability to drive and use machines has been reported, so this subject can use the drug.
7. Handling missed dose, overdose
Missed dose: If you forget to take a dose, take it as soon as you remember it as soon as possible. Never take a double dose to make up for a missed dose.
Overdose: Some cases of Rabeprazole overdose have been reported, however there is no specific antidote for Rabeprazole. Therefore, in case of overdose, symptomatic treatment and other supportive measures should be taken.
In case of emergency and danger, it is necessary to take the patient to the nearest medical facility for examination and timely treatment measures.
8. How to store
The drug should be stored in a dry place with a temperature below 30 degrees Celsius and should be protected from direct sunlight. Medicines should be kept out of reach of small children to avoid children playing and taking the wrong medicine.
Above is all information about the use of Rapeed 20mg drug, indications, usage, dosage, contraindications, cautions of the drug that everyone needs to know to use the drug to ensure good treatment effect. best and safest.
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