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Qbisalic topical is a medication commonly used to reduce the inflammatory manifestations of keratosis pilaris and corticosteroid-responsive dry skin disease. To better understand what is the use of Qbisalic medicine? What are the side effects of Qbisalic? What is the correct way to drink? What should be noted when using? The following article will help you better understand the topical drug Qbisalic.
1. What is Qbisalic drug?
Qbisalic drug is a drug in the group of drugs for the treatment of dermatological diseases such as psoriasis, chronic atopic dermatitis, neurodermatitis, eczema. Topical medicine qbisalic with ingredients Each 10g contains: Betamethasone dipropionate 0.0064 g; Salicylic Acid 0.3g.
1.1. Dosage form Skin ointment 1.2. Ingredients Each 10g contains: Betamethasone dipropionate 0.0064 g; Salicylic acid 0.3g
Qbisalic medicine contains main ingredients Each 10g contains: Betamethasone dipropionate 0.0064 g; Salicylic acid 0.3g other active ingredients and excipients with just enough drug content provided by the manufacturer.
1.3. Pharmacodynamics Betamethasone is a synthetic derivative of prednisolone. Betamethasone is an adrenal corticosteroid with anti-inflammatory properties. Betamethasone has potent anti-inflammatory, anti-arthritic and anti-allergic properties and is used in the treatment of corticosteroid-responsive disorders. As a glucocorticoid, Betamethasone exerts extensive and varied metabolic effects and reduces the body's resistance to stimuli. Betamethasone has high glucocorticoid activity and low mineralocorticoid activity. 1.4. Pharmacokinetics Absorption: Estradiol is well absorbed from the skin, mucous membranes and gastrointestinal tract. Distribution: The drug is widely distributed in the body and has high concentrations in sex hormone target organs. Approximately 60% of estradiol is bound to albumin in the blood, 38% is bound to sex hormone-binding globulin, and 2% is free. Metabolism: Estradiol is extensively metabolised in the liver, mainly to estrone, estriol and conjugates such as glucuronide or sulfate. Estradiol also undergoes enterohepatic recirculation via sulfate and glucuronic conjugation in the liver, excretion of bile conjugates into the intestine, and subsequent reabsorption into the bloodstream. Elimination: Estradiol is mainly excreted in the urine and a small amount in the faeces, less than 1% is excreted unchanged in the urine and 50-80% is excreted as conjugates.
2. What are the uses of Qbisalic?
Reduces inflammatory manifestations of keratosis pilaris & corticosteroid-responsive dry skin diseases such as psoriasis, chronic atopic dermatitis, neurodermatitis, eczema.
3. Qbisalic skin side effects
Possible heat, itching, irritation, dry skin, folliculitis , hirsutism, purulent rash, hypopigmentation, perioral dermatitis, contact allergy, skin rash, bacterial infection, skin atrophy, striped skin.
Decreased adrenal function, especially in children. When applied to a large area or covered with bandages, it can have a systemic effect.
Usually the side effects or unwanted effects (Adverse Drug Reaction (ADR) unwanted effects will go away when the drug is stopped. If there are rare side effects that are not mentioned in the leaflet. Inform your doctor or medical person immediately if you suspect any side effects of Qbisalic
4. Drug interactions
When using two or more drugs at the same time, it is easy to have drug interactions leading to antagonism or synergism.
4.1. Qbisalic drug interactions with other drugs Must stop hormonal contraceptives when appointing HRT. Patients should be instructed to use other methods of contraception if necessary. With prolonged treatment, certain drugs that induce liver enzymes (eg, some anticonvulsants and antibacterial agents) may increase sex hormone clearance and thereby reduce clinical symptoms. Such drugs that can induce liver enzymes are hydantoin, barbiturates, primidone, carbamazepine and rifampicin. Substances suspected of having this effect are oxcarbazepine, topiramate, felbamate, and griseofulvin. The liver enzyme-inducing effects of these drugs are generally maximal no earlier than 2-3 weeks but persist for at least 4 weeks after discontinuation of therapy. In rare cases, estradiol levels have been decreased when certain antibiotics are given concomitantly (eg, penicillins and tetracyclines). Substances whose metabolism undergoes glucuronic conjugation (eg, paracetamol) may increase the bioavailability of estradiol by competitively inhibiting the conjugate enzyme system for drug absorption. In individual cases, the need for oral antidiabetic drugs or insulin may change due to its effect on glucose tolerance. Interactions with alcohol: Drinking large amounts of alcohol during treatment with HRT can lead to increased levels of estradiol in the blood. Interactions with laboratory tests: Use of sex steroids can affect biochemical parameters, for example when testing liver, thyroid, adrenal, and renal function; changes in plasma protein levels of drug-binding proteins such as corticosteroid binding globulin and lipid/lipoprotein components, parameters of carbohydrate metabolism and parameters of coagulation, fibrinolysis. 4.2. Qbisalic drug interaction with food and drink When using the drug with foods or alcohol, beer, tobacco ... because in those foods and drinks contain other active ingredients, it may affect cause antagonism or synergism with the drug. Read the instructions for use carefully or consult your doctor or pharmacist about taking Qbisalic with food, alcohol and tobacco.
5. How to use Qbisalic topical skin effectively
5.1. How to use Qbisalic Drug Each drug, pharmaceutical product is produced in different forms and has different ways of using according to the route of administration. The usual routes of drug administration by drug form are: oral drugs, injections, external drugs and suppositories. Carefully read the instructions on how to take Qbisalic from the instructions for use of the drug, do not arbitrarily use the drug by other routes not listed on the Qbisalic drug user manual.
5.2. Dosage of Qbisalic Drug Apply to the infected skin area 2 times / day.
For adults
Dosing regulations are usually intended to guide adults taking oral medications. Dosage for other routes is specified in the leaflet. Do not change the dose on your own without consulting your doctor or pharmacist.
For children
Differences between children and adults such as pharmacokinetics, pharmacodynamics, side effects, etc., especially children, are not allowed to be included in clinical trials before being administered. new drug marketing authorization. Therefore, using this drug for children should be very careful even with drugs that have not been warned.
5.3. What to do in case of an overdose of Qbisalic Prescription drugs require a prescription from a doctor or pharmacist. Over-the-counter medicines require a leaflet from the manufacturer. Carefully read and follow the exact dose indicated on the prescription or medication leaflet. When taking an overdose of Qbisalic, you need to stop taking it, immediately notify your doctor or pharmacist when there are abnormal symptoms
Note to handle in case of overdose
Unusual manifestations of overdose need to notify the doctor or health care provider. In case of an overdose of Qbisalic, there are symptoms that require emergency: Call 911 immediately for guidance and help. Family members should bring medical records, all prescriptions/pots of medicine that have been and are being used so that doctors can quickly diagnose and treat
5.4. What to do if you miss a dose of Qbisalic Usually the medicine can be taken within 1-2 hours than prescribed in the prescription. Unless there is a strict rule about the time of use, the medicine can be taken a few hours after forgetting. However, if the time is too far from the time you need to drink, you should not take it, which can be dangerous for the body. It is necessary to strictly adhere to or consult a doctor before making a decision.
6. Be careful when taking medicine
6.1. Note before taking Qbisalic Women pregnant & lactating women. Avoid contact with eyes, mucous membranes, wounds.
6.2. Note to use Qbisalic drug during pregnancy General note during pregnancy: The drug used during pregnancy can cause adverse effects (miscarriage, teratogenicity, fetal malformation, ...) to any stage of pregnancy, especially the first trimester. Therefore, it is best not to use the drug for pregnant women. In the case of mandatory use, it is necessary to consult carefully with your doctor, pharmacist before making a decision.
6.3. Note taking drugs Qbisalic during lactation General note in the period when mothers are breastfeeding, the drug can be passed to the baby through breastfeeding. It is best not to or limit the use of the drug during breastfeeding. Many drugs have not been fully identified during this period, so you need to carefully read the instructions for use and consult your doctor and pharmacist before deciding to take the medicine.
7. How to store medicine
Store the medicine below 30 degrees Celsius and avoid moisture.
Be careful not to keep Qbisalic medicine out of the reach of children and away from pets.
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