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Pymeprim 480 is a drug with the main ingredients Trimethoprim 80mg, Sulfamethoxazol 400mg. The drug is used in the treatment of pneumonia, Toxoplasma disease, uncomplicated acute urinary tract infections, acute otitis media and acute exacerbation of chronic bronchitis. The following article will help you better understand the effects of this drug.
1. What is Pymeprim 480?
Pymeprim 480 is a bacteriostatic antibiotic, produced by Pymepharco joint stock company. The drug is prepared in the form of tablets, with the ingredient Sulfamethoxazol, which is a Sulfamide with bacteriostatic effect. Bacteriostatic mechanism by inhibiting bacterial production of dihydrofolic acid. The active ingredient Trimethoprim in the drug is a derivative of Pyridin that has the ability to kill bacteria. Mechanism of killing bacteria by inhibiting the enzyme Dihydrofolate reductase of bacteria. When these two antibiotic ingredients are combined, they will help prevent 2 consecutive reactions in the folic acid metabolism of bacteria, so they kill pathogenic bacteria and prevent drug resistance.
2. Indications for Pymeprim 480
Pymeprim 480 is indicated in the following cases:
Treatment of urinary tract infections. Treatment of respiratory tract infections: pneumonia,... Treatment and prevention of Toxoplasma disease. Treatment of genital tract infections. Treatment of acute otitis media. Treatment of acute exacerbations of chronic bronchitis.
3. Dosage and how to use Pymeprim 480
How to use: Pymeprim is used orally. The drug is not affected by food, so it can be taken with food or drink to minimize digestive disturbances.
Dosage:
Adults and children over 12 years old: Take 1 tablet / time / 12 hours. The specific dose depends on the medical condition and the degree of infection. Therefore, in special cases you should use it as prescribed by your doctor. Do not self-medicate, avoid antibiotic resistance or unwanted side effects.
4. Contraindications of Pymeprim 480
The drug should not be used in the following cases:
Patients with a history of hypersensitivity to Sulfamid or to Trimethoprim or any other excipients of the drug. Patients with severe renal impairment whose plasma drug levels cannot be checked regularly. Patients with megaloblastic anemia due to folic acid deficiency. Contraindicated in children under 2 months of age.
5. Precautions when using Pymeprim 480
During the use of Pymeprim, the following should be noted:
Patients with liver and kidney failure when taking the drug need to regularly evaluate the function. For patients who are elderly or with suspected folic acid deficiency, additional vitamins should be considered. Caution should be exercised when administering the drug to pregnant or lactating women.
6. Undesirable effects of Pymeprim 480
Common side effects:
Fever, nausea, vomiting. Diarrhea. Inflammation of the mouth, bad breath. Itching, skin rash. Uncommon side effects:
Purpura. Medal. Anaphylaxis . Decreased platelets, white blood cells. Jaundice, liver necrosis. CKD.
7. Pymeprim 480 . drug interactions
When using Pymeprim 480, the following drug interactions should be noted:
Diuretics, thiazides Warfarin, Phenytoin, Methotrexate, Phenylbutazone, Sulfinpyrazone. Antidiabetic drug, Cyclosporin. Rifampicin, when used concurrently with Pymeprim, will reduce the half-life of Trimethoprim. Indomethacin will increase the blood level of sulfamethoxazole.
8. Treatment when missed dose, overdose Pymeprim 480
If you miss a dose while taking Pymeprim, take it as soon as you remember. Do not take a double dose to make up for a dose you missed. If it is time for the next dose, skip the missed dose.
If you overdose on Pymeprim, you will experience symptoms: vomiting, nausea, dizziness, ... or any other unpleasant symptoms, please inform your doctor or go to the nearest medical facility. for prompt treatment.
In summary, Pymeprim 480 is a bacteriostatic antibiotic, which should be taken as prescribed by a doctor. So if you have any further questions about the drug, please consult your doctor/pharmacist for advice.
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