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Prezel 75 is an anticonvulsant and analgesic with the main ingredient pregabalin. To ensure effective use and avoid side effects, patients need to take the drug exactly as directed by the doctor, professional pharmacist.1. Indications of Prezel 75
Prezel 75 is an anticonvulsant and pain reliever with the main ingredient pregabalin. Prezel 75 is indicated in the following cases:
Peripheral and central neuropathic pain in adults. Adjunctive therapy in the treatment of partial seizures with or without secondary generalization in adults. Generalized anxiety disorder in adults.
2. How to take Prezel 75
How to use: Prezel 75 capsules are for oral use only, can be taken with or without food.
Dosage: 150 to 600 mg/day in 2 or 3 divided doses.
Neuropathic pain: Initial dose 150 mg/day divided into 2-3 oral doses, may increase dose to 300 mg/day after 3-7 days of treatment. Epilepsy: initial dose of 150 mg/day given in 2-3 divided doses, may be increased to 300 mg/day after 1 week of dosing. Generalized anxiety disorder: 150 to 600 mg/day in 2 or 3 divided doses. The condition should be reassessed regularly. Patients with hepatic impairment: No dosage adjustment necessary Children: The safety and efficacy of pregabalin in children under 12 years of age and adolescents (12-17 years of age) have not been established. No study data available. Elderly (>65 years): Elderly patients may require a reduction in the dose of pregabalin due to impaired renal function. at least 1 week according to each indication.
3. Contraindications of Prezel 75
Prezel 75 is contraindicated in the following patients:
Do not use the drug in patients with hypersensitivity to pregabalin or any of its ingredients. Children under 12 years old and adolescents (12-17 years old).
4. Be careful when using Prezel 75
Prezel 75 should be used with caution in the following cases:
Diabetic patients: dose adjustment of hypoglycemic agents may be required. Hypersensitivity Reactions: Post-marketing hypersensitivity reactions, including cases of angioedema. The drug should be discontinued immediately if symptoms of angioedema, facial swelling, swelling around the mouth or upper respiratory tract swelling occur. Treatment with pregabalin has been associated with dizziness and somnolence, which may increase the occurrence of accidental injuries such as falls in the elderly. Visual Effects: In controlled clinical trials, the incidence of blurred vision was higher in patients treated with pregabalin than in patients treated with placebo. Adverse visual acuity reactions have also been reported, including blindness, blurred vision or other changes in visual acuity, most of which are transient. Renal Impairment: Cases of renal failure have been reported and in some cases discontinuation of pregabalin may reduce adverse reactions. Discontinuation symptoms: Symptoms such as insomnia, headache, nausea, diarrhea, flu syndrome, anxiety, nervousness, depression, convulsions, pain, increased sweating and dizziness. Convulsions may occur during the use of Prezel 75 or immediately after discontinuation of the drug. Congestive heart failure: Congestive heart failure has been reported in some patients treated with pregabalin. Suicidal intention and behavior: has been reported in subjects treated with antiepileptic agents. Patients should therefore be monitored for signs of suicidal behavior and appropriate treatment should be considered. Substance abuse: Caution should be exercised in patients with a history of substance abuse and patients should be monitored for symptoms of pregabalin abuse. Driving and using machines: Prezel 75 may affect the ability to drive and use machines. Because the drug can cause dizziness and drowsiness, do not drive, operate machinery, or engage in hazardous activities while taking this medicine.
Pregnancy: Prezel 75 should not be used during pregnancy unless clearly needed (if the potential benefit to the mother outweighs the potential risk to the fetus).
Women of childbearing age: Because the risks of taking Prezel 75 are not fully known. Therefore, women of childbearing age should use contraception in women of childbearing potential.
Lactation : It is not known whether the drug is excreted in breast milk. However, the drug was present in the milk of rats. Therefore, breastfeeding should be discontinued during treatment with pregabalin.
5. Undesirable effects of the drug Prezel 75
The most common side effects of Prezel 75 are dizziness and drowsiness. Other side effects of the drug such as increased intestinal motility, euphoria, confusion, irritability, decreased libido, disorientation, insomnia, ataxia, motor coordination abnormalities, tremor, dysarthria, memory impairment, attention disorder, paresthesia, sedation, vestibular disturbance, coma, headache, blurred vision, double vision, vomiting, dry mouth, constipation , flatulence, erectile dysfunction, abnormal gait, feeling drunk, fatigue, peripheral edema, edema, weight gain.
In summary, Prezel 75 is an anticonvulsant and analgesic with the main ingredient being pregabalin. To ensure effective use and avoid side effects, patients need to use the drug exactly as directed by the doctor, professional pharmacist.
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