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Prega 50 is a medicine that is effective in the treatment of pain caused by nerves. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to take the drug according to the prescription or consult a doctor, professional pharmacist.
1. Uses of Prega 50
Prega 50 medicine has the main active ingredient is pregabalin 50mg. It is a gamma aminobutyric acid (GABA) analogue, namely (S)-3 - (aminomethyl)-5-methyl hexamoic acid. Despite its similar structure, it does not bind to GABA receptors, but rather binds to the complement subunit (alpha 2-delta protein) of the central nervous system. Although the mechanism is not completely clear, when used it helps to reduce nerve transmission. Therefore, the drug is used to treat some of the following diseases:
Treatment of neuropathic pain of central and peripheral nervous origin. Treatment of generalized anxiety disorder in adults. Adjunctive treatment in partial epilepsy with or without generalization in adults.
2. Usage and dosage of Prega 50
The drug is in the form of tablets, the patient should be taken with water and can be taken with or without food.Dosage: The average dose is 150 to 600mg/day, divided into two or three times daily.
Pain due to neuropathy: Treatment with pregabalin can be started at a dose of 150mg/day. Depending on individual patient response and tolerability, the dose may be increased to 300 mg/day at intervals of 3 to 7 days and may be increased to a maximum dose of 600 mg/day after the next 7 days if absolutely necessary. set.
Epilepsy: Treatment with prega 50 can be initiated at a dose of 150 mg/day. Depending on individual patient response and tolerability, the dose may be increased to 300 mg/day after 1 week. The dose may be increased to a maximum of 600 mg/day 1 week after the 300 mg dose. Generalized anxiety states: Patients can be initiated on prega 50 at a dose of 150 mg/day. Depending on individual patient response and tolerability, the dose may be increased to 300 mg/day 1 week after dosing. After the next 1 week, the dose can be increased to 450mg/day. A maximum dose of 600 mg/day can be used if needed after another week. Note: Specific dosage depends on the condition and progress of each patient. To get the most appropriate dose, patients need to consult and consult a doctor.
Possible Overdose: In cases of overdosage of about 15g, the most common adverse reactions reported with overdose were somnolence, confusional state, excessive agitation, hyperactivity. limbs. When an overdose of the drug is used, the patient needs to go to a medical facility for treatment, measures include symptomatic treatment, may require hemodialysis if treatment is not stable.
3. Possible side effects when treated with Prega 50
When using Prega 50, patients may experience unwanted effects including:
Allergy to the drug causing angioedema, allergic reactions, may occur severe allergic reactions with manifestations such as difficulty breathing, abdominal pain, swelling of the face, swelling of the throat... need emergency treatment. Decrease in neutrophils in the blood. Increased appetite or loss of appetite. Better mood, confusion, excitability, decreased sex drive. Dizziness, dizziness, somnolence, ataxia, abnormal movement coordination, tremor, difficulty speaking, slurred speech, memory loss, difficulty concentrating, paresthesia such as numbness or tingling cow ants. Blurred vision, decreased vision, dizziness, double vision. Tachycardia, which can cause congestive heart failure. Abnormal gait, drunken sensation, fatigue, peripheral edema. Hot flashes, shortness of breath, dry nose, weight gain, vestibular dysfunction, erectile dysfunction... Withdrawal syndrome: After stopping the drug through a short or long-term treatment with pregabalin, there have been cases of the occurrence of withdrawal syndrome. The following phenomena were noted in the report: Insomnia, headache, nausea, diarrhea, flu syndrome, excitability, depression, increased pain sensation, sweating and dizziness, dizziness. . Patients should be informed of this at the start of treatment and monitored after stopping treatment with this drug. When experiencing side effects of prega 50, patients need to stop using and notify this to their doctor or if serious, they should immediately go to the nearest medical facility for timely treatment.
4. Note when using Prega 50
The drug is not used for people who are sensitive to the ingredients of the drug. Therefore, before taking this medicine you need to tell your doctor about any history of allergy to the drug or any other allergic condition. Use with caution in the following subjects: Patients with renal failure, diabetes mellitus, cardiovascular disease, predisposing factors for brain disease, and older age. Patients with rare hereditary problems of galactose intolerance, lapp-lactase deficiency or glucose-galactose malabsorption should not take this medicine. The drug can cause drowsiness, dizziness, so patients should not operate machinery and drive vehicles, because there is a risk of accidents. Although the relationship of high dose or long-term use has not been found to affect and cause withdrawal syndrome after drug discontinuation. However, if necessary, the drug should be discontinued gradually for a minimum of 1 week. Special populations: people under 18 years of age, because safety and efficacy have not been established, are not recommended for use; Pregnancy and lactation have not been studied for safety in these two subjects, so do not use unless the benefit outweighs the risk to the baby. As with other antiepileptic drugs, the use of this drug is associated with factors such as suicidal ideation and behavior, and drug abuse. Patients should be closely monitored, especially those at risk. The drug is eliminated in its pure form by the kidneys and there is almost no obvious interaction with other drugs. Prega 50 is a medicine used to treat pain caused by nerves. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to take the drug according to the prescription or consult a doctor, professional pharmacist.
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