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Pharmaclofen is a muscle relaxant that acts on the central nervous system. Often indicated for use in cases of muscle spasms caused by spinal cord or brain causes, scleroderma. So how should Pharmaclofen be used?1. What is Pharmaclofen?
The main ingredient of Pharmaclofen is Baclofen 10mg with the dosage form of tablets. Baclofen is a muscle relaxant, chemically baclofen structurally similar to gamma-aminobutyric acid (GABA), a neurotransmitter in the brain. So, like GABA, Baclofen blocks the nerves that form the brain's reticular organization and these nerves control muscles. Baclofen works by blocking nerve activity in the spinal cord, so it reduces muscle spasms and stiffness caused by traumatic brain and spinal cord injuries, strokes or nerve concussions such as multiple sclerosis. In addition, Baclofen also works to prevent hiccups. It is one of the most effective medications used to treat chronic hiccups of various etiologies.
2. Uses of Pharmaclofen
Pharmaclofen is indicated for use in the following cases:
Treatment of conditions that cause spasms such as excessive skeletal muscle spasms. Disseminated sclerosis. Other spinal cord injuries such as myeloma, spinal cord hollow disease, motor neuron diseases, spinal cord injury, transverse myelitis. Stroke. Paralysis due to cerebral causes; Meningitis ; Head injury
3. Dosage and usage of Pharmaclofen
How to use: Pharmaclofen is taken orally.
Dosage: Dosage depends on the individual and the specific disease.
This drug should be started with the lowest possible dose and then gradually increased to achieve an optimal response. The usual dose is from 40 to 80 mg, which is about 4 - 8 Pharmaclofen tablets. Recommended dosing regimen:
Take 5mg of baclofen (1⁄2 Pharmaclofen tablets) and take 3 times a day for 3 days. Take 10 mg of baclofen (1 Pharmaclofen tablet) and take 3 times a day for 3 days. Take 15 mg of baclofen (1.5 Pharmaclofen tablets), and 3 times a day for 3 days. Take another 20mg of baclofen (2 Pharmaclofen tablets), 3 times a day for 3 days. The dose may then be increased further depending on response and tolerability but not exceeding 80 mg. The lowest dose should be used for optimal results. If after a period of taking the drug does not bring results, do not stop abruptly, but gradually reduce the dose and then stop.
Overdose:
When taking the drug in very high doses you may experience symptoms such as: Profuse vomiting, decreased muscle tone, drowsiness, endocrine disruption, coma, respiratory depression, and convulsions. jerk. Overdose signs and symptoms are aggravated by alcohol, diazepam, or tricyclic antidepressants. Treatment: Treat symptomatically and induce vomiting followed by gastric lavage. For patients who are no longer awake, before gastric lavage need to be intubated, do not induce vomiting. It is necessary to closely monitor and support the patient's symptoms.
4. Pharmaclofen side effects
When using Pharmaclofen you may also experience unwanted effects, including:
Common side effects: Lower blood pressure; Nausea, constipation; Urinating a lot. Uncommon side effects: Shortness of breath, palpitations, chest pain, fainting; Dry mouth, loss of appetite, taste disturbances, abdominal pain, vomiting, diarrhea, blood in stools... When experiencing side effects of Pharmaclofen, you need to stop using it and notify your doctor or pharmacist. Go to the nearest medical facility for prompt treatment.
5. What should be noted when taking Pharmaclofen
Pharmaclofen is contraindicated when you are sensitive to baclofen or any of the excipients in the drug. Before using the drug, you need to talk to your doctor about your medical history, history of allergies and need carefully instructions for use. Do not stop abruptly: As this occurs visual hallucinations, auditory hallucinations, confusion, anxiety occur with tachycardia and sweating, insomnia, and worsening muscle spasticity. It is necessary to gradually reduce the drug to avoid this situation. Patients with impaired renal function: Because this drug is excreted by the kidneys, the dose should be reduced as necessary. Particular caution should be exercised when administering the drug to patients with epilepsy or a history of convulsions. The patient's condition and EEG should be regularly evaluated because the patient's convulsive status and EEG symptoms may occasionally appear. worsened during treatment with baclofen. The drug should be used with caution in patients with gastrointestinal ulcers, severe mental disorders, the elderly with cerebrovascular disease, and patients taking antihypertensive drugs. Pregnancy: The effect of Baclofen on the fetus is unknown, and the benefits and risks need to be carefully weighed before using this drug for this population. Lactation: The amount excreted in breast milk of baclofen is found to be too small to be dangerous, but you should still consult your doctor or pharmacist before taking it. Drug interactions: Before using, it is necessary to inform the doctor when taking drugs such as tricyclic antidepressants, capillary blockers, central nervous system depressants, ibuprofen, antihypertensive drugs, diuretics , antidiabetic drugs, carbidopa/levodopa drugs, alcohol. Storage: In a dry place, the temperature is below 30 degrees Celsius. Keep the medicine out of the reach of children. Above is information about the uses, doses, and uses of Pharmaclofen. You need to follow the instructions exactly to be able to use the drug safely.
