This is an automatically translated article.
Oztis 750 mg is indicated for the treatment of pain relief, anti-inflammatory, cartilage regeneration in arthritis, osteoarthritis, osteoarthritis, rheumatoid arthritis, acute and chronic rheumatism.1. What is Oztis?
The drug Oztis (Glucosamine sulfate and Chondroitin sulfate) has been shown to be safe when used in the indicated doses. There are no clinical reports of side effects, but patients with diabetes should follow their doctor's instructions when taking the drug daily. Oztis has the main ingredients are Glucosamine sulfate 750mg and Chondroitin sulfate 250mg. Belongs to the list of drugs in the system of bones and joints. The drug is prepared in the form of film-coated tablets by Lipa Pharmaceuticals Pty.Ltd. – Australian production.Brand Name: Oztis. Class: Antipyretic analgesics, non-steroidal anti-inflammatory drugs (NSAIDs). Oztis is prescribed by doctors to treat the symptoms of mild to moderate osteoarthritis of the knee.
Chondroitin is a naturally occurring substance formed from chains of sugars. Chondroitin is thought by researchers to help the body maintain the required amount of fluid and flexibility in the joints. Glucosamine is a sugar protein that helps your body build cartilage (a type of hard connective tissue located mainly on bones near your joints). Glucosamine is a naturally occurring substance found in bone marrow, bones, shellfish, and fungi.
Oztis is a specially formulated Chondroitin and glucosamine product that has been used in alternative medicine as an aid to help maintain connective tissue function and functioning. joint. Using drugs for elderly patients helps joints to move more flexibly, maintaining regular use of the drug will create elasticity and increase nutrition for joint cartilage, creating flexibility for joints.
Other uses not proven through research include treating osteoporosis, rheumatoid arthritis, glaucoma, cataracts, bladder problems, high cholesterol, heart disease, or TMJ (joint disease). temporomandibular).
2. What are the uses of Oztis?
Oztis is a drug capable of maintaining the activity of connective tissue and bone and joint function, helping them to move flexibly and supple, especially in elderly subjects. Regular use of Oztis can increase nutrients for cartilage and joints, help joints increase elasticity, and improve function.2.1. Pharmacodynamics of the drug Oztis
Glucosamine is a component of glycosaminoglycans, polysaccharides and glycosphingolipids, which are also the structural components of all living cells. In addition, glycosaminoglycans are also basic substances for the formation of synovial fluid, articular cartilage, spinal discs, cell walls, lung tissue and the lining of the small intestine. The active ingredient Glucosamine sulfate has many different mechanisms of action. Among them, it must be mentioned that it inhibits the degeneration of proteoglycans (the foundation structure of articular cartilage), helps restore joint damage caused in experimental studies, has anti-arthritic effects and protects cells. cartilage cells. In addition, Glucosamine sulfate has a very mild anti-inflammatory and anti-edema effect. Clinically, Glucosamine sulfate is preferred by doctors to treat osteoarthritis and fight osteoarthritis. Glucosamine sulfate helps maintain healthy joint connective tissue and function. Regular use helps to strengthen the elasticity of joints and nourish joint cartilage. Chondroitin sulfate is a polysaccharide compound - a glycosaminoglycan that participates in the structure of cell membranes, contributes to the composition of the elastic fibers of large blood vessels, accounts for a large proportion in cartilage and bone tissue, ensures that bone cartilage not only has strength but also elasticity, is an important material in the process of regeneration of cartilage and bone tissue. Has the effect of preventing cell degeneration. Maintain the elasticity of structures with many elastic fibers such as tendons, fascia, ligaments. Chondroitin inhibits elastase, a mediator in cartilage degeneration, and activates proteoglycan synthesis by chondrocytes.Glucosamine and chondroitin are recognized as "chondroprotective" - substances that protect joint cartilage. Chondroprotective is a natural active substance produced by the body to regenerate damaged joint cartilage and increase the flexibility of joints. Chondroprotective active ingredients have the effect of enhancing the synthesis of articular cartilage cells, while maintaining the lubrication of joints, increasing the lubrication between joints. In addition, Glucosamine and Chondroitin fight enzymes that destroy joint cartilage, to ensure easier blood flow into joints. Clinical trials have demonstrated that Glucosamine and Chondroitin slow down the destruction of joint cartilage in osteoarthritis and degenerative joint diseases.
2.2. Pharmacokinetics of Oztis Absorption:
Glucosamine and Chondroitin are almost completely absorbed orally (reaching 90 to 98%). Distribution:
Immediately after administration of 20 minutes Glucosamine is bound to plasma α and β globulin, plasma concentrations peak after 8 to 10 hours, then decrease gradually, the half-life of the drug is more than 2 days. . Glucosamine is actively absorbed by articular cartilage and some tissues, while most other tissues are passively diffused. Elimination:
When radiolabelled glucosamine sulfate is administered, clearance of radioactivity is mainly via the lungs (50%) as carbon dioxide, kidneys (35%) as glucosamine, and faeces (approximately 2%). . 2.3. Contraindications of the drug Oztis Patients who are allergic to any of the ingredients of the drug Oztis; Pregnant and lactating women; Children under 18. 2.4. Side effects when using Oztis Mainly gastrointestinal side effects such as belching, heartburn, epigastric pain and diarrhea.
2.5. Drug interactions Consult a doctor if symptoms do not improve after taking the drug. May lead to increased insulin resistance when taking Glucosamine and thus affect the user's glucose tolerance. Using glucosamine as prescribed by your doctor for patients with diabetes requires frequent blood sugar checks and may require an adjustment in the dose of blood sugar control drugs the patient is taking. Take the medicine exactly as directed by the doctor. Taking the drug with Heparin increases the risk of bleeding. There are no known drug interactions with other drugs, nutritional supplements, supplements or herbs. 2.6. Precautions while using oztis 750 mg If symptoms do not improve, it is necessary to consult a doctor. The main source of Chondroitin and Glucosamine sulfate is from marine animals. Therefore, consult your doctor before using this medicine if you are allergic to seafood. As noted above, insulin resistance can be increased by glucosamine. The subjects of the study were normal healthy animals and animals with diabetes who were given Glucosamine to increase insulin resistance. In these animals, intravenously tested glucosamine significantly reduced the extent of glucose absorption in skeletal muscle. Patients with type 2 diabetes or those who are overweight or have problems with glucose tolerance should have their blood sugar checked periodically if they are taking glucosamine supplements. 3. How to use Oztis 750 mg effectively Glucosamine sulfate and Chondroitin sulfate have been shown to be safe when used in the indicated doses. There are no clinical reports of side effects, but patients with diabetes should follow their doctor's instructions when taking the drug daily, as it has the potential to interfere with enzymes necessary for maintaining blood sugar levels. blood sugar.
How to use:
Take orally directly, do not crush tablets or mix with other mixtures. Dosage:
For people over 18 years old: Take 2 times a day, 1 tablet each time, or as directed by a doctor. The duration of drug use depends on the individual, at least continuously for 2 to 3 months to ensure the effectiveness of treatment; No dose adjustment is required for the elderly. There are no studies in subjects with hepatic and/or renal impairment. Caution should be exercised in patients with severe hepatic and/or severe renal impairment. 4. Storing the medicine Oztis 750 mg Store the medicine at room temperature, below 30 degrees Celsius. Avoid placing the medicine in a place with direct light (near a window, balcony) or a humid place (bathroom, basement). Do not use Oztis medicine beyond the expiry date, which is deformed. Talk more with experts, pharmacists to have the right and appropriate way to handle the drug.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
