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Ostikar is indicated in the treatment of symptoms of osteoarthritis... Let's learn about the uses, the notes when using Ostikar through the article below.
1. Uses of Ostikar
“What is Ostikar?”. Ostikar contains the active ingredient Diacerein 50mg, which is prepared in the form of hard capsules. Ostikar is indicated in the following cases:
People with arthritis or joint cartilage-related diseases; Symptomatic treatment of painful inflammatory diseases such as chronic osteoarthritis, fractures, extra-articular rheumatism, postoperative pain and inflammation, soft tissue injuries, trauma, dental procedures.
2. Mechanism of action
Diacerein belongs to the Antraquinone group of drugs, has anti-inflammatory effects through the mechanism of inhibiting the formation and activity of Interleukin - active substances that cause inflammation and play an important role in the inflammatory process. Diacerein has the effect of reducing the concentration and activity of Interleukin, thereby helping to reduce the process of cartilage degeneration in patients with osteoarthritis.Scientific studies show that Diacerein reduces proinflammatory factors and affects the anabolism and catabolism of chondrocytes. In addition, Diacerein also showed inhibitory effects on macrophage phagocytosis and migration. Studies in animal models of osteoarthritis have shown that Diacerein consistently reduces cartilage degeneration compared with the untreated group.
3. Dosage of Ostikar
Ostikar belongs to the group of prescription drugs, so the dose of medicine used is prescribed by the doctor based on the patient's condition.
Some recommendations on the dosage of Ostikar are as follows:
For 2 weeks: Take 1 tablet/time x 1 time/day; From the following weeks take 1 tablet / time x 2 times / day. The drug should be taken after meals with a suitable amount of water. Note that the dose of Ostikar presented above is for reference only, patients need to use the drug according to the dose and time prescribed by the doctor.
4. Ostikar . side effects
Ostikar may cause some side effects as follows:
Abdominal pain is common in the first 2-4 weeks of taking the drug; Dark urine, which is caused by the metabolic components of the drug, is not dangerous to the patient. Patients should inform their doctor if they experience any side effects during treatment with Ostikar.
5. Notes when using Ostikar
Contraindicated to use Ostikar in the following cases:
Patients with hypersensitivity to Diacerein or any component of Ostikar; Patients with intestinal obstruction, gastroenteritis, abdominal pain because of the high risk of complications such as gastrointestinal bleeding, intestinal perforation... Caution should be taken when using Ostikar in the following cases:
Caution when using Ostikar use of Ostikar in children under 15 years of age; For pregnant women: It is necessary to weigh the benefits and risks before using Ostikar; For lactating women: Diacerein and its metabolites are excreted in breast milk, so the drug should not be used in lactating women; Store Ostikar at room temperature (below 30oC), away from direct sunlight and high humidity.
6. Drug interactions
Drugs that neutralize stomach acid such as Hydroxide of Calcium, aluminum... reduce the effect of Diacerein. Therefore, these drugs should be taken at least 2 hours apart.
Drug interactions occur that increase the risk of having effects and reduce the therapeutic effects of Ostikar, so to ensure safety and effectiveness in treating patients, it is necessary to inform doctors about drugs and foods. are using before taking Ostikar.
Above is all information about Ostikar, patients need to carefully read the instructions for use, consult a doctor / pharmacist before using. Note, Ostikar is a prescription drug, patients need to use the drug as prescribed by the doctor, absolutely do not self-treat at home.
