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Ocebaten is used in the treatment of allergic symptoms of rhinitis, conjunctivitis or idiopathic urticaria. Let's learn about the dosage, usage and indications of Ocebaten through the article below.1. What is Ocebaten?
Ocebaten is used in patients with frequent allergic rhinitis and chronic urticaria. The drug has the main ingredient is Esbatine with a concentration of 20mg in each tablet, taken orally.2. Uses of Ocebaten
Ocebaten with the main ingredient is Esbatine, this is a drug belonging to the 2nd generation antihistamine group. After entering the body, Esbatine will be metabolized to form another substance with Carebastine activity.
A quite obvious advantage of Ocebaten is that it is effective against allergies and inhibits bronchospasm in asthmatic patients. For patients with year-round allergic rhinitis due to weather, Ocebaten works to reduce sneezing and runny, stuffy nose.
According to statistics from clinical trials, patients who used Ocebaten for a long time, even daily, did not have any symptoms of drug resistance or loss of drug effects. Pharmacokinetics: Ocebaten is rapidly absorbed from the gastrointestinal tract after oral administration. In patients receiving a dose of 10 mg, the drug will reach peak plasma concentrations of 80-100 ng/ml between 2 and 4 hours. Ocebaten drug can completely cross the placenta and excreted through the breast-feeding mother. In terms of elimination, 2⁄3 of Ocebaten will be excreted in the urine as conjugated metabolites. The mean half-life of Ocebaten is 15-19 hours, which can be increased to 23-27 hours in patients with renal or hepatic impairment.
Drug interactions: Ocebaten should not be used with Ketoconazole, Itraconazole, Erythromycin, Clarithromycin, Josamycin because it can easily cause cardiac arrhythmias in susceptible individuals.
Ocebaten should not be taken near meals, as both food and milk have the potential to increase drug concentrations.
3. Indications for taking Ocebaten
Patients with seasonal allergic rhinitis, according to the weather, all year round. Allergic conjunctivitis. Idiopathic urticaria (chronic disease).
4. Contraindications to taking Ocebaten
Contraindicated to use Ocebaten for patients with hypersensitivity to Ebastin 20mg components contained in the drug and patients with severe liver failure.
5. Dosage and how to use Ocebaten
Ocebaten is taken orally. The appropriate time to take the drug is 3 hours before or after a meal to avoid food that can increase the plasma concentration of Ocebaten.
Dosage:
For patients with allergic rhinitis take 1-2 tablets/day; For patients with chronic idiopathic urticaria: 1 tablet/day; For patients with mild to moderate hepatic impairment: 1 tablet/day.
6. Side effects of the drug Ocebaten
For body systems, when taking Ocebaten, there is a risk of side effects, specifically as follows:
Mild side effects: Sore throat, indigestion, digestive disorders, weakness, loss of appetite. sleep, nausea. Rare side effects in organ systems:
Cardiovascular system: Palpitations with increased heart rate. Body as a whole: Asthenia, background edema. Digestive system: Dry mouth, indigestion, abdominal pain, nausea. Central nervous system: Headache, somnolence, dizziness, nervousness Genitourinary system: Menstrual disorders. Allergies, urticaria, dermatitis.
7. Note when using Ocebaten
Need to be careful when using Ocebaten with hypokalemic patients With patients being treated with drug groups including Ketoconazole, Itraconazole, Erythromycin, Clarithromycin, Josamycin, there must be intervention and evaluation of the condition from a doctor. . Use with caution in patients with renal impairment Caution should be exercised when using Ocebaten in pregnant or lactating women. According to clinical experiments, Ocebaten does not affect the ability to use machines or drive a vehicle. However, to ensure safety, users need to monitor their reactions after taking the drug for a while before driving or operating machinery. Ocebaten with Esbatine 20mg is a medicine for the treatment of seasonal allergic rhinitis or idiopathic urticaria. Taking the right medicine at the right dose, on time and according to the doctor's prescription will help the treatment process to be significantly effective.