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Nilutamide drug has the active ingredient name Nilutamide and other excipients in a sufficient amount. Nilutamide is used in the treatment of metastatic prostate cancer, as an aid in orchiectomy in the treatment of metastatic prostate cancer involving lymph nodes, bones or internal organs.
1. What is Nilutamide?
Generic Name (Active ingredient): Nilutamide Drug Type: Cancer hormone, androgen antagonist or testosterone inhibitor. Drug form and strength: 150 mg tablets. Most prostate cancers require a supply of the male hormone testosterone to grow. Testosterone is a hormone produced by the testes and adrenal glands. Anti-hormonal drugs work by blocking Testosterone receptors and preventing Testosterone from binding to these receptors in prostate cells. Without Testosterone, cancer cells may grow more slowly or stop growing altogether.
Nilutamide drug is used in the treatment of metastatic prostate cancer, supporting orchiectomy in the treatment of metastatic prostate cancer.
2. How to use Nilutamide
Nilutamide is available in the form of tablets. The use of the drug is not affected by the presence or absence of food. However, you should still take your medicine at the same time each day so you don't forget to take it.
It is important that you make sure you are taking the correct amount of medicine each time. Before each dose of treatment, you need to check the information to see if it matches what you have been prescribed.
3. Nilutamide drug interactions
Nilutamide can cause alcohol intolerance with symptoms including flushing, irritability, and low blood pressure. You should avoid consuming alcoholic beverages while using this medicine.
Nilutamide blood levels can be affected by certain foods and drugs, so it is important to use these drugs together. Drugs that can interact with Nilutamide drugs are: Rifampin, Fluconazole, Fluoxetine, Fluvoxamine, Voriconazole. You need to tell your treating doctor about all the medicines and supplements you take to minimize possible adverse interactions while taking them.
4. How to store Nilutamide
You should store Nilutamide at room temperature, in its original packaging. If you prefer to use a pill container, discuss this with your oncologist. Do not flush Nilutamide tablets down the toilet or throw them in the trash.
5. Where you can buy Nilutamide medicine
Nilutamide is available at retail pharmacies. The medical facility you are treating will work with the prescription drug program to identify a retail pharmacy to dispense the drug.
6. Undesirable effects of the drug Nilutamide
Some things you can do to manage the side effects of Nilutamide. Here are some of the most common or important side effects when using Nilutamide:
Pneumonia: When using Nilutamide, you can get pneumonia. The warning signs of pneumonia when using the drug include difficulty breathing, cough, chest pain and fever. Hot flashes: When using Nilutamide, you may experience symptoms of hot flashes. Several medications have been shown to help relieve symptoms, including Clonidine (a blood pressure medication), low therapeutic doses of certain antidepressants (such as Venlafaxine, Fluoxetine), and Gabapentin. At the same time, you can make lifestyle changes to reduce hot flashes, including:
Drink enough water from 6 to 8 glasses of water daily. Drink ice or apply ice at the onset of a hot flash. Wear lightweight, breathable cotton or fabric clothing and wear layers so you can adjust as needed. Do gentle exercise on a regular basis. Try meditation or relaxation exercises to reduce feelings of stress, which can trigger hot flashes. Avoid triggers such as spicy foods, caffeinated beverages, and alcohol.
Vision changes: Nilutamide can affect how your vision adapts when going from bright areas to darker areas. Vision changes can range from a few seconds to several minutes. When experiencing this undesirable effect you should be cautious when driving at night or through tunnels and consider wearing sunglasses or tinted sunglasses to control this side effect. Nilutamide may also cause other vision changes or changes in color vision.
Weakening of bones (osteoporosis): Men on long-term hormone therapy have an increased risk of developing osteoporosis (osteoporosis). You may be advised to take calcium and vitamin D supplements to help prevent bone loss. Exercising to withstand weight and maintaining a healthy diet rich in calcium and vitamin D can also help protect your bone health. You may have bone density monitoring (DEXA scan) to assess your bone health. If your treating doctor determines that you are at high risk for osteoporosis, he or she may prescribe additional treatment with a medicine called a bisphosphonate to help strengthen your bones.
Breast engorgement or breast tissue enlargement : An increase in breast tissue (gynecomastia) or breast engorgement may develop. Your doctor may prescribe medications to relieve pain. In rare cases, radiation may be given to soothe severe pain.
Less common side effects than liver toxicity: Nilutamide can cause liver toxicity, the treating doctor will monitor it with blood tests or liver function tests. Some possible signs of hepatitis when using this medicine include: yellow skin or eyes, dark or brown urine, or pain in your abdomen.
7. Effects of drugs on fertility
Nilutamide can affect your reproductive system, resulting in sperm production becoming irregular or permanently stopping. In addition, men may experience erectile dysfunction or decreased sex drive during treatment.
Talk to your orthopedic doctor about choosing methods to treat erectile dysfunction.
Nilutamide drug has the active ingredient name Nilutamide and other excipients in a sufficient amount. Nilutamide is used in the treatment of metastatic prostate cancer, as an aid in orchiectomy in the treatment of metastatic prostate cancer involving lymph nodes, bones or internal organs. To ensure the effectiveness of treatment and avoid side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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Reference source: oncolink.org
