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Moov 7.5 is a non-steroidal anti-inflammatory drug indicated in the treatment of antipyretic, analgesic, anti-inflammatory and antiplatelet, but the antipyretic effect is poor. The drug is mainly indicated in bone and joint diseases such as joint damage, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis.
1. What is Moov 7.5?
Moov 7.5 is a strong non-steroidal anti-inflammatory drug (NSAID) of the oxicam family, which helps with inflammation, pain, fever, and platelet aggregation. However, the antipyretic effect is poor, so it is mainly used in pain relief and anti-inflammatory. In addition, the drug also penetrates well into the synovial and inflammatory tissues, poorly penetrates the nervous tissue, so it causes less side effects on the nervous system.
Moov 7.5 has a mean bioavailability of 89%, and plasma concentrations with doses of 7.5 mg and 15 mg have been reported from 0.4 to 1 mg/l and from 0.8 to 2 mg/l, respectively. The drug is strongly bound to plasma proteins, mainly albumin (99%), is extensively metabolised, has a mean half-life of 20 hours, and is excreted in the feces and urine at a ratio of 50:50.
2. Uses of Moov 7.5
Moov 7.5 is indicated in the treatment of pain caused by chronic inflammation in osteoarthritis diseases such as: joint damage, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis.
The anti-inflammatory mechanism is due to the ability to inhibit the biosynthesis of prostaglandins, mediators of inflammation. In vivo, moov 7.5 inhibits prostaglandin biosynthesis more strongly at the site of inflammation than in gastric mucosa or kidney.
2. Dosage, how to use Moov 7.5
Moov 7.5 drug has different dosage depending on the purpose of treatment:
For people with rheumatoid arthritis, ankylosing spondylitis: 2 tablets/day, the dose can be reduced to 1 tablet/day if the response is good. . For people with osteoarthritis pain: 1 tablet / day, can increase to 2 tablets / day if the pain does not subside. For people with many underlying diseases, the risk of side effects is high, so only 1 tablet / day should be started. People with severe kidney failure, requiring hemodialysis should not take more than 1 tablet per day. When used in combination with oral and injectable forms, the total dose should not exceed 15 mg/day. The intramuscular route is used only on the first day of treatment, then continued orally. This medication must be given by deep intramuscular injection, not an intramuscular tube for intravenous administration. The drug Moov 7.5 is only limited to adults. The drug is taken with water or other liquid drinks and is not impaired when taken with food.
3. Contraindications to Moov 7.5
Moov 7.5 is contraindicated in the following subjects:
History of allergy to moov 7.5 or drugs with some similar ingredients Sensitivity to aspirin and other non-steroidal anti-inflammatory drugs, history of asthma, Nasal polyps, angioedema, urticaria after taking aspirin and other nonsteroidal anti-inflammatory drugs peptic ulcer, severe liver failure, severe renal failure Children under 15 years of age, pregnant and lactating women
4. Moov drug interactions 7.5
Moov 7.5 should not be used in combination with some of the following drugs because it increases the risk of side effects:
Other non-steroidal anti-inflammatory and analgesic drugs because of an increased risk of gastrointestinal bleeding Anticoagulants, drugs that make thrombolytics (ticlopidine, heparin) because of the increased risk of bleeding. Lithium increases plasma concentrations of lithium. Methotrexate because of increased toxicity on the hematopoietic system. Contraceptive devices because they reduce the effectiveness of contraceptives Caution should be taken when administering moov 7.5 with the following drug classes:
Diuretics because of the increased risk of acute renal failure in dehydrated patients Antihypertensive drugs ( such as beta-blockers, ACE inhibitors, vasodilators, diuretics) because of reduced antihypertensive effect Cholestyramine increases the elimination of moov 7.5 by binding in the gastrointestinal tract Ciclosporin because moov 7.5 increases Ciclosporin nephrotoxicity. Not recommended for pregnant or lactating women
5. Moov 7.5 . side effects
Moov 7.5 may cause some of the following side effects:
Gastrointestinal symptoms such as abdominal pain, constipation, diarrhea, flatulence, vomiting, etc. Blood count disorders (thrombocytopenia, white blood cell count). ), anemia, which if used in combination with myelotoxic drugs may become a contributing factor in bone marrow depression Some skin reactions such as itching, rash, urticaria, stomatitis Acute asthma attacks but very rare Causes dizziness, headache, tinnitus, somnolence Causes angioedema, increased blood pressure, palpitations, flushing Causes elevation of creatinine and blood urea nitrogen anaphylaxis Moov 7.5 should not be used as a substitute for corticosteroids, or treatment of corticosteroids deficiency. Reactions such as jaundice, acute hepatitis causing liver failure, liver necrosis, even death are very rare. Hopefully, sharing about the use of Moov 7.5 will help the process of using the drug in treatment more effectively and safely for the health of patients.
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