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Macnir 50 mg drug with the main active ingredient is Eperisone hydrochloride (Eperisone), often indicated to improve symptoms of hypertonia or spastic paralysis. So how does Macnir affect the body?
1. Effects of the drug Macnir
Macnir 50 mg drug has the main active ingredient is Eperisone hydrochloride (Eperisone) 50 mg content. Eperisone is a class of antispasmodic drugs whose mechanism of action is by blocking the pressure channel. When the muscle is contracted, it can disrupt blood circulation, then cause pain and increase muscle tone, causing more muscle contraction. Eperison will break this pathological cycle. Thanks to its action on the central nervous system and vascular smooth muscle, Eperisone has the following effects:
Reduces spinal reflexes (acting mainly on the spinal cord) and relaxes skeletal muscle, improving symptoms associated with hypertonia. Vasodilation, increases circulation. Macnir has little or no sedative effect. Eperison has a good effect on relaxing skeletal muscle and vascular smooth muscle, and also has many other effects such as reducing myasthenia gravis, improving circulatory function and inhibiting pain reflex.
Macnir drug is usually indicated in the following cases:
Spasticity caused by: cerebrovascular disease, myelopathy, cervical spondylosis, postoperative sequelae. Improvement of symptoms associated with hypertonia in cervical spondylosis. Inflammation around the shoulder and lumbar joints.
2. How to take Macnir
Macnir 50 mg is made in the form of film-coated tablets, the drug is taken orally.
The usual recommended dosage is 1 tablet / time x 3 times / day, taken after each meal. However, depending on the age, weight, physical condition and medical condition of each person, the dose can be adjusted accordingly.
3. Notes when using the drug Macnir
3.1. Contraindications Note, do not use Macnir for the following cases:
Children under 18 years of age. Patients who are allergic or sensitive to the drug or any of its ingredients. 3.2. Side effects Macnir 50 mg usually causes very few side effects. However, it is still necessary to pay attention to monitoring while taking the drug and to contact emergency medical attention if you experience serious and prolonged side effects. Common side effects are:
Hypersensitivity reactions: Rash, itching, edema, difficulty breathing,... Serious skin disorders: Skin redness, peeling, skin with blisters, blisters or may bleed Heavy blood in lips, eyes, nose,... Liver: Increased liver enzymes. Kidney: Presence of proteinuria. Hematology: Anemia, abnormal red blood cell count or hemoglobin value in the blood. Neuropsychiatric: Headache, drowsiness or insomnia, spasticity, numbness, tremor of the extremities,... Gastrointestinal: Nausea, vomiting, anorexia, dry mouth, constipation, diarrhea, abdominal pain,. .. Urinary: Urinary retention, urinary incontinence, feeling of incomplete urination,... Whole body: Fatigue, dizziness, dizziness, excessive muscle tone reduction,... Other: Hot flushes, vomiting sweat, nervousness, palpitations,... 3.3. Note when using the drug Macnir Should be considered and used with caution in special populations:
Pregnant or lactating women: Macnir 50 mg is not recommended for use in pregnant or nursing women. breast-feeding unless absolutely necessary. The benefit-risk factor should be weighed before use in this population. Elderly: Macnir should be used with caution in the elderly because the risk of serious side effects may be higher in this age group. It is necessary to closely monitor the drug, if necessary, adjust the appropriate dose or replace it with another more suitable drug based on the clinical condition of the patient. Children: Macnir is not recommended for use in patients under 18 years of age, as safety and efficacy in this age group have not been clinically proven. Driving or operating machinery: Macnir 50 mg may cause side effects such as dizziness, lightheadedness in some patients. Therefore, the use of the drug should be considered in people who regularly perform activities that require high alertness, such as driving or operating heavy machinery. If you experience symptoms of dizziness while taking the drug, you should not do tasks that require high concentration. Disturbances of eye accommodation have been observed following concomitant administration of tolperison (a drug structurally similar to Eperison) with methocarbamol (a CNS muscle relaxant). Therefore, close monitoring is required when Macnir is co-administered with drugs containing methocarbamol.
Macnir 50 mg has good effect in relaxing skeletal muscle and vascular smooth muscle. When taking the medicine, it should be used exactly as prescribed by the doctor. In the process of taking the drug, if you experience any unusual side effects, you need to contact emergency medical help for timely support.
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