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Loacne drug has the main ingredients cyproterone acetate and ethinylestradiol, indicated in the treatment of acne caused by androgen sensitivity. How should Loacne be used?
1. What are the effects of Loacne?
Loacne is indicated in the treatment of:
Moderate to severe acne due to androgen sensitivity. Hirsutism in women of childbearing age. Note: For the treatment of acne, Loacne should only be used when topical treatment or systemic antibiotics are ineffective. Since Loacne also has a hormonal contraceptive effect, it should not be used concurrently with other hormonal contraceptives.
2. How to use Locne
Loacne drug is taken orally, 1 tablet per day at the same time of day, for 21 consecutive days, then stop for 7 days. Repeat the same dosing schedule with subsequent courses of treatment.
3. Undesirable effects of the drug Loacne
When using Loacne, patients may experience undesirable effects such as:
Common: Nausea, abdominal pain, weight gain, headache, nervous disorders, depression, mood swings, pain breast, breast tightness. Uncommon: Vomiting, diarrhea, migraine, fluid retention, breast enlargement, decreased libido, rash, urticaria.
4. Contraindications of the drug Loacne
Loacne is contraindicated in the following subjects:
History of venous thrombosis History of cerebrovascular disorders. History of myocardial infarction or coronary artery disease. Acute liver disease, past or present liver tumor, cholestatic jaundice. Breast carcinoma. The tumor is estrogen-dependent. Abnormal vaginal bleeding. Visual damage due to eye vascular disease Pregnant women. Hypersensitivity to any of the ingredients of the drug. Are taking other hormonal birth control pills. Having risk factors for venous or arterial thrombosis such as: diabetes with vascular symptoms, severe dyslipoproteinemia, severe hypertension. Inherited or acquired factors for arterial or venous thromboembolism include antithrombin III deficiency, activated protein C resistance, protein S deficiency, protein C deficiency, hyperhomocysteinemia, and antiphospholipid antibodies (anticardiolipin antibodies). , lupus anticoagulant).
5. Be careful when using Loacne
Assess the patient's health condition before taking Loacne, including measuring blood pressure and, if necessary, examining the chest, abdomen and gynecology.
Exclude the possibility of pregnancy before starting the drug.
Unexplained vaginal bleeding that needs examination and monitoring.
Discontinue Loacne if: diabetes, concomitant mild vascular disease or kidney disease, manageable hypertension, retinopathy or neuropathy; porphyria, obesity, migraine, clinical depression, cardiovascular disease, melasma.
Monitor patients with a history of depression during treatment with Loacne .
Pregnancy: absolute contraindication and the possibility of pregnancy must be excluded before treatment is started. If pregnancy occurs during treatment with loacne, the drug must be discontinued.
Lactation: Use during lactation may lead to a decrease in milk volume and a change in the composition of the milk. Breastfeeding women should stop taking the drug or stop breastfeeding.
6. Loacne drug interactions
Inducers of liver enzymes (particularly cytochrome P450 3A4) increase the metabolism of oral contraceptives, thereby possibly causing bleeding or unintended pregnancy. The following classes of drugs can cause serious interactions: antivirals (ritonavir, nelfinavir,...); anticonvulsants (barbiturates, primidone, phenytoin,...); antibiotics/antifungals (griseofulvin, rifampacin), herbal medicines (St. John's Wort).
Effects on other drugs: Oral contraceptives and estrogen/progestogen combinations such as cyproterone acetate and ethinylestrdiol may affect the metabolism of other drugs.
In addition to the information about the drug Loacne shared above, if you have any questions, you should contact your doctor for advice and appropriate indications.
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