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Litapyl 200 belongs to the group of cardiovascular drugs, with the main active ingredient being Fenofibrate 200mg. So, Litapyl 200 is indicated for use in which cases? What precautions should be taken when using Litapyl 200? Let's find out information about the drug Litapyl in the following article.
1. What is Litapyl 200?
Litapyl 200 belongs to the group of cardiovascular drugs, used to treat hypercholesterolemia, persistent hyperlipoproteinemia, or hypertriglyceridemia alone/in combination when unresponsive to diet and measures. Do not take other drugs.
Litapyl 200 is composed of the main active ingredient, Fenofibrate 200mg. Excipients with sufficient content of 1 tablet include: Avicel M101, corn starch, primellose, HPMC 606, sodium lauryl sulfate, magnesium stearate, aerosil).
Litapyl 200 is available in the form of tablets, elongated, white, edged and a healthy member. The drug is packaged in a box of 3 blisters x 10 tablets; Box of 10 blisters x 10 tablets.
2. What are the effects of Litapyl 200?
Litapyl 200 medicine has the main ingredient is Fenofibrate, this is an active ingredient that can reduce blood cholesterol by 20-25% and reduce blood triglycerides by 40-50%.
Litapyl 200 is indicated as an adjunct to diet and other non-pharmacological treatment as follows:
Treatment of hypertriglyceridemia alone/in combination when unresponsive to diet and non-pharmacological measures other. Treatment of mixed hyperlipidemia in statin intolerance. Mixed hyperlipidemia in patients at high cardiovascular risk plus a statin when triglycerides and HDL cholesterol are not adequately controlled. Persistent hyperlipoproteinemia (eg, dyslipidemia in diabetes mellitus).
3. How to use Litapyl 200
3.1. How to use the drug Litapyl 200 For the drug Litapyl 200, users use it orally. Patients coordinate with the diet, take the drug at the main meal.
3.2. Dosage of Litapyl 200 Drug dosage recommendations for specific subjects are as follows:
For adults: The recommended initial dose is 200mg, 300mg and 160mg Fenofibrate tablets to be taken once a day. For the elderly (≥ 65 years): In elderly patients, the usual adult dose is recommended. For children: The safety and effectiveness of fenofibrate in children and adolescents under 18 years of age have not been established. Therefore, the use of Fenofibrate is not recommended for people under 18 years of age. If necessary, it can be used up to 5mg/kg/day for children > 10 years old. For patients with renal impairment: Fenofibrate should not be used if renal impairment is severe. Dosage of Fenofibrate should not exceed the standard 100mg or 67mg granules once daily. For patients with hepatic impairment: Litapyl 200 is not recommended for use in patients with hepatic impairment due to lack of data. 3.3. How to handle in case of forgetting, overdosing Missed dose:
If a dose of Litayl 200 is forgotten, usually patients can take it within 1-2 hours compared to prescribed in the prescription. Unless there is a strict prescription of the treating doctor about the time of use, it can be taken a few hours after forgetting. However, if it is too far ahead of time, skip the missed dose and use the next dose as directed.
Overdose:
In the majority of cases of Litapyl 200 overdose, no specific symptoms were reported.
If an overdose of Litapyl 200 is suspected, it is necessary to stop taking it, immediately notify the treating doctor or pharmacist for timely handling. Family members need to bring medical records, all prescriptions being used so that doctors can quickly come up with a treatment plan. Fenofibrate cannot be eliminated by hemodialysis.
3.4. Contraindications Litapyl 200: Contraindicated Litapyl 200 in the following cases:
Patients with allergies, hypersensitivity to the active ingredient Fenofibrate or any of the excipients of the drug. Contraindicated in young children (< 10 years old). Liver failure (including biliary cirrhosis and unexplained persistent liver function abnormalities). Gallbladder disease. Severe kidney failure. Acute or chronic pancreatitis excludes acute pancreatitis due to severe hypertriglyceridemia. Photoallergic reactions or toxic effects of light are known during treatment with fibrates or ke-toprofen (non-steroidal anti-inflammatory).
4. Notes when using Litapyl 200:
Caution should be taken when using Litapyl 200 in the following cases:
The patient's liver and kidney function must be tested before treatment with Litapyl 200. Consider additional or alternative therapy if after 3 to 6 months treatment without a decrease in blood lipid levels. For liver function: The increase in transaminase levels is temporary, mild, and asymptomatic. Transaminases should be monitored every 3 months for the first 12 months of treatment. Discontinue use of Litapyl 200 if symptoms of hepatitis (yellowing of the skin, itching, etc.) appear. If fenofibrate is combined with oral anticoagulants, the anticoagulant dose should be adjusted accordingly during treatment with fenofibrate and monitoring of blood prothrombin levels should be enhanced. People with cholestatic cirrhosis or gallstones: prone to biliary complications (obstruction of bile ducts). Regularly check your blood count. Use in pregnancy: Use only after careful benefit/risk assessment. Use in lactation: There are no data on the excretion of fenofibrate 200 mg and/or its metabolites in human milk. Therefore, Fenofibrate 200mg tablets should not be used by nursing women. Effects on ability to drive and use machines: Litapyl 200 has no or negligible influence. Side effects of Litapyl 200:
With the use of Litapyl 200, the following undesirable effects were observed in placebo-controlled clinical trials with the frequencies indicated below. :
Common:
Gastrointestinal disorders: Gastrointestinal signs and symptoms (abdominal pain, nausea, vomiting, diarrhea, flatulence). Hepatobiliary disorders: Increased transaminases. Uncommon:
Nervous system disorders: Headache. Thromboembolism (pulmonary embolism, deep vein thrombosis). Hepatobiliary disorders: Gallstones. Skin hypersensitivity (rash, pruritus, urticaria). Muscle spasms, muscle weakness, pain, myositis. Sexual dysfunction. Increased blood creatinine. Rare:
Blood and lymphatic system disorders: Decreased hemoglobin, decreased white blood cell count. Immune system disorders: Hypersensitivity. Hepatitis. Hair loss, photosensitivity disorder. Increased blood urea. If you experience any unwanted side effects, stop taking the medicine and notify your doctor immediately.
Litapyl 200 Drug Interactions:
Consider taking Litapyl 200 with tobacco, alcohol, alcoholic or fermented beverages, which may increase the risk of muscle problems.
Use caution when using any of the following medicines:
Anticoagulants that thin the blood (eg warfarin). Other medicines to control the amount of lipids (fats) in the blood (for example medicines called “statins” or “fibrates”). Taking a statin at the same time as fenofibrate may increase your risk of muscle problems. Ciclosporin (immunosuppressive drug). Medicines to control type 2 diabetes (glitazone). Storage of Litapyl 200:
Store the medicine at room temperature, avoid direct sunlight or high temperature.
Above is all necessary information and notes when using Litapyl 200. To ensure safety when using the drug, patients need to consult a doctor or pharmacist before use. Hopefully the article has provided you with all the necessary information about Litapyl 200.
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