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Levzal 500 drug with the main ingredient is Levofloxacin, belonging to the group of drugs to treat parasites, anti-infectives, antivirals, antifungals. So what exactly is Levzal 500 and what is the dose? Find out more information about Levzal 500 in the article below.
1. What is Levzal 500?
Levzal 500 is a prescription drug that has anti-infective effects and treats diseases caused by bacteria. Levzal 500 is prepared in the form of film-coated tablets, in a package of 10 tablets in a blister, packed in a blister with a cardboard box. 5 such small boxes inside one big box. Levzal 500 drug is composed of the main drug, Levofloxacin 500 mg, here is extracted in the form of Levofloxacin hemihydrate 500 mg, with the main use being to treat diseases caused by bacterial infections.
2. What does Levzal 500 do?
Levzal 500 is made from Levofloxacin 500 mg and other excipients just enough for one tablet. Levofloxacin is a quinolone antibacterial agent that inhibits bacterial DNA synthesis, replication and encoding. This active substance has a higher bactericidal effect than the inhibitory concentration.
The specific effects of Levofloxacin are listed as follows:
Treatment of symptoms of infections caused by anaerobic or gram-positive aerobic bacteria Treatment of infectious diseases such as respiratory tract infections , urinary tract infections, infections caused by bacteria sensitive to Levofloxacin. Levzal 500 is indicated for use in the following patients:
Patients with acute sinusitis, patients experiencing acute exacerbation of chronic bronchitis Patients with pneumonia, bacterial infections in the respiratory tract due to the invasion of anaerobic bacteria: Streptococcus, Staphylococcus, Pneumococcus,.. Patients with community-acquired pneumonia Patients with urinary tract and urinary tract infections, including nephritis Disease infections of the skin, mucous membranes and soft tissues.
3. Usage of Levzal 500
3.1. How to use Levzal 500 For Levzal 500, patients use it orally. Dosage of Levza depends on the degree of infection and the patient's ability to absorb it. The duration of use of the drug can be extended based on the severity of the infection area, up to a maximum of 14 days.
Take Levzal 500 by swallowing the tablet whole with a glass of liquid, such as cooled boiled water. Patients should be reminded not to break, crush or chew the product as these behaviors may result in loss of the pharmacokinetics of Levzal 500.
3.2. Levzal 500 Dosage Levzal 500 is indicated for use in adults and children. For people with normal kidney function, the recommended dose for each disease symptom is as follows:
Dosage for patients with acute sinusitis: Use 1 tablet, once a day, for a duration of 10 hours. up to 14 days. Dosage for chronic sinus patients with severe acute attack: Use 1 tablet, once a day, for a duration of 7 days. Dosage for patients with pneumonia in the community: Use 1 tablet, once a day, for treatment within 7 days. Dosage for patients with urinary tract infections, including nephritis: Use 250 mg, once a day, treat within 10 days Dosage for patients with uncomplicated sinus infections: Use 500 mg, 1 time per day, treatment time from 7 to 10 days. Dosage for patients with infections of the skin, mucous membranes: Use a dose of 250 mg 2 times a day or 500 mg 1 time a day, the duration of treatment is from 7 to 14 days. For adult patients with impaired renal function (creatinine clearance less than 50 ml/min:
Adult patients with impaired renal function: Dosage varies depending on severity of infection. Patients with impaired liver function: No dosage adjustment is necessary Elderly patients: No dose adjustment is required, however, special attention should be paid to renal function in elderly patients. Contraindicated for use in children and adolescents 3.3 Treatment of missed dose, overdose Missed dose: When a dose is missed, the patient should take it as soon as possible, but when the time to remember it is almost time to take it. Next dose, continue to take Levzal 500 as prescribed by your doctor. Note absolutely do not take a double dose, avoid reactions caused by overdose.
Overdose: In case the patient uses it. Overdose of Levzal, unwanted symptoms of the drug may appear. At this time, the patient needs to be treated symptomatically. Accordingly, you should go to the doctor. nearest medical facility to conduct an electrocardiogram test, due to the risk of QT prolongation. Patients can take antacids to protect the stomach lining.
Treatments such as hemodialysis, peritoneal dialysis and long-term peritoneal dialysis do not remove Levofloxacin from the body.
3.4. Contraindications Levzal 500 is contraindicated in patients who are allergic or hypersensitive to Levofloxacin or any of its ingredients. Levzal is contraindicated in patients with epilepsy, convulsions Patients with a history of tendon rupture related to the use of fluoroquinolones Contraindications to the use of Levzal 500 in children or adolescents Contraindications to the use of Levzal 500 for pregnant women, lactating mothers.
4. Note when using Levzal 500
Side effects of Levzal 500
When using Levzal 500, patients may experience unwanted side effects such as:
Unwanted reactions may include: insomnia, dizziness, vomiting, abdominal pain, dyspepsia, rash, adnexitis, flatulence, pruritus,... Reactions are possible but rare: euphoria, agitation, loss of appetite, anxiety, dry mouth occur , allergic reactions include: skin edema, vaginal itching, increased sweating, sore throat, .. Reactions are possible but very rare: use of Levofloxacin can cause heart failure, increased blood pressure. , bad breath, even the occurrence of cardiovascular risks such as myocardial infarction or purpura,... In special cases, sleep disturbances, liver dysfunction, platelets, and functional disorders may occur. kidneys,... Precipitation in the urine has been reported with the use of other quinolones. Patients should report the side effects they have encountered when using Levzal 500 to the doctor for timely adjustments.
Drug Interactions Levzal 500
Antacids containing iron, magnesium or aluminum salts: A decrease in the effect of Levofloxacin has been observed when co-administered with this drug. It should be used at least 2 hours after using Levzal 500. Combined use of Levofloxacin with Sucrafate may reduce the activity of the drug. Levofloxacin concentrations are 13% higher when used in combination with fenbufen than when used alone. Levofloxacin should be used with caution in combination with drugs that affect renal excretion, such as probenicid or cimetidine, especially in patients with renal impairment. Vitamin K antagonists: May increase blood clotting test results or increase bleeding time, conduct blood clotting time monitoring when taking these two drugs together. Store Levzal 500
Avoid leaving Levzal 50 in humid places, do not leave the medicine out of the manufacturer's packaging when not in use. The appropriate storage temperature for Levzal 500 is below 30 degrees Celsius, avoiding direct sunlight on the product. Keep Levzal 500 out of the reach of children & pets Levzal 500 is a prescription medicine, so it can only be purchased and used by patients with a doctor's prescription. Please read the instructions for use carefully before use and follow the instructions and dosage prescribed by your doctor.
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