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Levibact 500 is a prescription drug that requires a doctor's prescription before use. The drug is used to treat acute infections in the organs of the body, with antibacterial properties belonging to the quinlon group of antibiotics.
1. What is Levibact 500?
Levibact 500 is a drug indicated for use in the treatment of bacterial infections. The drug is produced in the form of tablets, with box packaging, in each box there is 1 blister containing 5 tablets. Levibact 500 belongs to the group of fluoroquinolone antibiotics.
Levibact 500 is made up of the main active ingredient, Levofloxacin, here it is extracted in the form of Levofloxacin hemihydrate 500mg and other excipients just enough for one tablet. Levofloxacin in the drug Levibact has an antibacterial task by inhibiting the bacterial gyrase enzyme, thereby reducing the number of bacteria.
2. What does Levibact 500 do?
Levibact 500 has the active ingredient Levofloxacin 500 mg. Levofloxacin is an antibacterial agent of the quinolone group. The explanation for the mechanism of action of this drug is as follows: Levofloxacin inhibits the enzyme DNA gyrase, also known as topoisomerase II of bacteria. This is an enzyme that affects DNA replication and assembly. The active ingredient Levofloxacin has a higher bactericidal effect than the inhibitory concentration.
The effects of Levofloxacin include:
Broad-spectrum antibacterial and active against gram-positive aerobic or anaerobic bacteria. Treatment of infections caused by bacteria sensitive to Levofloxacin. Levibact 500 is indicated for use in the following cases:
Patients with acute maxillary sinusitis Patients with community-acquired pneumonia Patients with uncomplicated skin mucosal infections Patients with bacterial infections with urinary tract complications Patients with nephritis, especially acute pyelonephritis Use with caution in patients with acute bacterial infections, with a history of chronic bronchitis. Because Levefloxacin may be harmful to this person. Use only when no other treatment options are available.
3. Usage of Levibact 500
3.1. How to use Levibact 500 For Levibact 500, patients absorb and use it orally. Take Levibact tablets by swallowing them whole with a moderate amount of liquid, such as cooled boiled water. Do not break tablets to divide doses, chew or crush tablets as this may lose the effectiveness of Levibact 500.
Consult your doctor's dosage as dosages may vary depending on response or goal of treatment. different use.
3.2. Dosage of Levibact 500 Use 500mg per day for the diseases mentioned above or as directed by a physician. Reference doses for patients with renal impairment are as follows:
Creatinine clearance between 50 and 80 ml/min: No dose adjustment necessary Creatinine clearance from 20 to less than 50 ml/min: Initial dose is 500 mg, then Oral maintenance 250 mg per day Creatinine clearance from 10 to less than 20 ml/min: Initial dose is 500 mg, then maintenance oral 125 mg per day Patients with complicated urinary tract infections, patients with Acute pyelonephritis or pyelonephritis:
Creatinine clearance above 20 ml/min: Initial dose is 250 mg, then maintenance oral dose of 250 mg daily Creatinine clearance from 10 to less than 20 ml/min: Initial dose 250 mg, then 250 mg once every two days. 3.3. Handling when forgetting, overdosing Missed dose:
Take Levibact 500 immediately when you remember. If it is almost time for your next dose, take your usual dose. Never take two doses to make up for the missed dose.
Overdose:
Overdosage of Levofloxacin can cause acute poisoning. Monitor the patient and make sure electrolytes are adequate. Hemodialysis does not remove Levofloxacin. In the event of a serious overdose, call 911 and take the patient to the nearest hospital for prompt treatment.
3.4. Contraindications Levibact 500 Patients with known hypersensitivity to Levofloxacin or any antibacterial agent of the quinolone class. Patients with severe renal impairment: consider using Levibact 500 with caution Not recommended for patients with acute infections of chronic bronchitis Women who are pregnant, suspected of being pregnant or breast-feeding Children children under 15 years old
4. Note when using Levibact 500
4.1 Side effects of Levibact 500 When using Levibact 500, patients may experience the following undesirable side effects:
Nervous system disorders: headache, insomnia, anxiety, headache digestive system disorders: diarrhea, flatulence, abdominal pain, taste disturbances, constipation,... Immune system related disorders: itchy rash, urticaria Infections such as yin inflammation Vaginal discharge, genital candidiasis, vaginal discharge, increased sweating Patients should inform their doctor about the undesirable effects encountered when taking Levibact 500
4.2 Levibact 500 Drug Interactions Concurrent use of Levofloxacin with antiretroviral drugs Aluminum and magnesium-based acids, drugs containing metal cations can reduce the absorption of Levofloxacin from the gastrointestinal system, resulting in lower-than-desired concentrations of Levofloxacin. Adverse reactions such as convulsions may occur when theophyllin is used with Levofloxacin. Monitor and adjust dose appropriately. Concomitant use of Levofloxacin with non-steroidal anti-inflammatory drugs (NSAIDs) may increase central nervous system excitability, increasing the risk of convulsions. There is a probability of hyperglycaemia when quinolones are co-administered with antidiabetic drugs. 4.3 Storing Levibact 500 Tablets Store Levibact 500 mg in a dry, well-ventilated place. Store unused medicine in the manufacturer's sealed container The storage temperature for Levibact is at room temperature, below 30 degrees Celsius. Never leave the medicine in a place where children can reach Levibact 500 is a prescription drug. , specialized for the treatment of bacterial infections and bactericidal. Patients should follow the instructions of the treating doctor, read the instructions carefully before using Levibact 500.
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