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Lessenol Extra 500mg is made in the form of film-coated tablets, containing Paracetamol and Caffeine. The drug is indicated for use to relieve pain in many diseases, reduce fever, ...
1. Uses of the drug Lessenol Extra
Lessenol 500 Extra has ingredients including: Paracetamol 500mg and Caffeine 65mg. The drug is a combination of Paracetamol and Caffeine, providing fast pain relief, fever reduction with high efficiency.
Paracetamol acts centrally - peripherally, helps relieve pain, lowers temperature by inhibiting the activity of cyclooxygenase enzyme in the synthesis of Prostaglandin (the substance that causes fever, inflammation, pain in the body). Paracetamol has a strong hypothermic effect due to its effects on the hypothalamus, vasodilation and increased peripheral blood flow. And caffeine has a mild stimulant effect on the central nervous system, supporting pain relief and supporting muscle activity.
Lessenol Extra is indicated for use in the following cases:
Fast and effective relief of pain including: Headache, migraine, menstrual pain, sore throat, pain after tooth extraction or procedures dental pain, toothache, arthritis pain, muscle and tendon pain, injury pain, sinusitis, cold or flu pain; Rapid fever reduction. Lessenol Extra is contraindicated in the following cases:
People who are sensitive or allergic to the ingredients of the drug; Patients with anemia, lung, heart or liver disease; People with G6PD deficiency.
2. Usage and dosage of Lessenol Extra
Usage: Orally. Tablets should be taken whole with filtered or boiled water.
Dosage: For adults and children over 12 years old, take 1 4 times a day, 1-2 tablets each time. Patients should not take more than 8 pills per day. The minimum interval between 2 doses of Lessenol Extra is 4 hours.
Overdose: Paracetamol overdose due to taking a single toxic dose or taking repeated large doses of Paracetamol (7.5 - 10g per day, for 1-2 days) or by taking the drug for a long time. The risk of dose-dependent liver necrosis is the most serious side effect of overdose, which can be fatal. Manifestations of overdose are nausea, vomiting, abdominal pain, cyanosis in the skin, mucous membranes and nails. When intoxication with Paracetamol is severe, the patient is treated with active support, gastric lavage (preferably within 4 hours after taking the drug). The patient was then prescribed appropriate antidote therapy.
Missed dose: If a dose of Lessenol Extra is missed, the patient should take it as soon as he remembers. After that, you should wait 4-6 hours before taking the next dose if needed.
3. Lessenol Extra side effects
Some side effects patients may experience when using Lessenol Extra include:
Uncommon: Skin rash, nausea, vomiting, neutropenia, pancytopenia, leukopenia, anemia, kidney disease, nephrotoxicity with long-term drug abuse; Rare: Hypersensitivity reactions, possibly causing liver failure (due to hepatocellular destruction) with prolonged, high doses of the drug. Patients should inform their doctor about the side effects they experience while taking the drug to receive appropriate advice.
4. Be careful when using Lessenol Extra
Some precautions for patients to remember before and during the use of Lessenol Extra:
Use caution when administering the drug in patients with pre-existing anemia because cyanosis may not be evident; Drinking a lot of alcohol can increase the toxicity of Paracetamol to the liver, so when taking the drug, patients should avoid or limit alcohol consumption; Lessenol Extra is not recommended for children under 12 years of age; Do not exceed the indicated dose; Not recommended for use in pregnant and lactating women (as directed by a doctor).
5. Lessenol Extra drug interactions
Some drug interactions of Lessenol Extra include:
Taking Paracetamol (the main ingredient of Lessenol Extra) for a long time with high doses will slightly increase the anticoagulant effect of Coumarin and Indandion derivatives; Be aware of the potential for severe hypothermia when phenothiazines are co-administered with antipyretic therapy; Anticonvulsants (such as Phenytoin, Barbiturates, Carbamazepine) induce enzymes in the liver microsomes, which may increase the risk of liver damage of Paracetamol by increasing the metabolism of the drug into substances that are toxic to the liver; Concomitant use of Isoniazid with Paracetamol may increase the risk of hepatotoxicity; Caffeine may interact with drugs that inhibit, are metabolized, or induce the CYP1A2 enzyme. To ensure safety and effectiveness when using Lessenol Extra 500mg, patients should inform their doctor about any medications they are taking and their medical history. At the same time, during the course of taking the drug, if you experience unusual side effects, the patient should also notify the doctor immediately.
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