This is an automatically translated article.
Lamzitrio medicine contains active ingredients including Lamivudine 150mg, Nevirapine 200mg and Zidovudine 300mg which are made in the form of long film coated tablets. Lamitrio belongs to the group of drugs that inhibit enzymes (enzymes) and nucleotide reverse transcriptase. So what disease does Lamzitrio treat and how to use it?
1. Uses of the drug Lamzitrio
1.1. Indications for use Lamzitrio Lamzitrio is indicated for the treatment of HIV infection in adults and children 12 years of age and older, increasing immunity.
Medicines help reduce the amount of HIV in the body so that the immune system can work better, reducing your risk of HIV complications such as cancer and new infections and improving your quality of life.
1.2. Contraindications to using Lamzitrio To avoid unwanted side effects, Lamzitrio should not be used for the following subjects:
Patients with severe liver failure. The patient is hypersensitive to any of the ingredients of the drug. The patient had a history of rash accompanied by atopic symptoms or hepatotoxicity due to nevirapine. Patients with low neutrophil counts (<0.75 x 109/l) or low hemoglobin levels (<7.5 g/dl or 4.65 mmol/l).
2. Dosage and how to use Lamzitrio
Usage: The drug is used orally and the quality of the drug is not affected by food. Lamzitrio should only be used at the start of individual drug therapy for 6 to 8 weeks once stable on nevirapine 200 mg twice daily.
Users can refer to the dosage as follows:
Adults and adolescents ≥ 16 years old or older or weighing ≥ 50kg: take 1 tablet x 2 times/day. Patients with severe liver failure or reduced kidney function (ClCr ≤ 50 ml/min): Do not use the drug. Patients with mild to moderate hepatic impairment: No dose adjustment is required. Note: If you forget to take a dose, just take the next dose and continue taking it as recommended. Do not take a double dose at the same time to make up for a missed dose.
The above recommended therapeutic drug dosage for Lamzitrio is for reference only. Therefore, users need to use the drug under the advice of a doctor to ensure safety and achieve the best effect.
3. Lamzitrio side effects
Some unwanted side effects when using Lamzitrio include:
Headache, fatigue, irritability, cramps Anemia, neutropenia Digestive disorders with manifestations: nausea, vomiting and diarrhea Increased liver enzymes , alkaline phosphatase and bilirubin Rash, hair loss; muscle pain; Hypersensitivity reactions When unusual symptoms or undesirable effects appear, immediately stop using the drug and consult a doctor. If there are rare side effects or not mentioned in the instructions for use. Tell your doctor right away if you suspect any side effects.
4. Lamzitrio drug interactions
Some interactions with Lamzitrio include:
Avoid concomitant use with ribavirin or stavudine. Consider taking the drug with alcohol, tobacco, alcoholic beverages, or fermentation because it can change the ingredients in the medicine.
5. Some notes when using Lamzitrio
During the use of Lamzitrio, caution should be exercised in the following cases:
Patients with moderate hepatic impairment. People with anemia or bone marrow failure. Patients with chronic hepatitis B or C infection. People with liver disease or other risk factors for liver disease. It is necessary to actively monitor the following cases:
Special vigilance during 6 weeks of treatment with adverse skin reactions and hepatotoxicity during the first 18 weeks of treatment. Lipids and blood glucose. Patients with signs of hepatotoxicity such as anorexia, nausea, jaundice, bilirubinuria, pale stools, enlarged or tender liver. The patient had stopped taking the drug but had signs of HBV replication, poor liver function, and HBV coinfection. Lamzitrio should be discontinued immediately in the event of:
Progressive abdominal pain, nausea, vomiting or abnormal biochemical test results until pancreatitis has been ruled out. There are signs/symptoms or abnormal pancreatitis-related laboratory results. Rash, severe rash accompanied by atopic symptoms such as fever, blistering, mouth ulcers, conjunctivitis, facial edema, muscle or joint pain, or general malaise or hypersensitivity reactions, or inflammation clinical liver. The concentration of aminotransferase enzyme increases rapidly People with unexplained metabolic acidosis or lactic acidosis, progressive hepatomegaly. Patients using Lamzitrio should note:
Patients with pain and stiffness, stiffness or difficulty in movement should seek medical advice. HIV-infected mothers should not breast-feed and should only be given the drug to pregnant women when the benefits and risks have been weighed. Drivers and machine operators need to be careful when using the drug. Hopefully, the information shared about the uses, usage and some necessary notes about Lamzitrio will help users understand and use the drug safely.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
