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Lamozit is a drug containing a mixture of active ingredients Lamivudine and Zidovudine. So what are the uses of Lamozit and how to use it properly? Please read the article below for more information about Lamozit.
1. What is Lamozide?
Lamozit is a drug containing the main ingredient of a mixture of Lamivudin and Zidovudine. In particular, Lamivudin is an antiviral drug that is well absorbed from the digestive system with bioavailability in adults when used usually reaching 80-85%. This active ingredient is highly active against hepatitis B virus in all cell lines tested and in infected laboratory animals and should be used for the treatment of chronic hepatitis B in patients 16 years of age and older with evidence of hepatitis B virus (HBV) replication.
Zidovudine is a potent antiviral agent in vitro against retroviruses, including human immunodeficiency virus (HIV).
2. Uses of Lamozit
Lamozit is indicated for use in the treatment of chronic hepatitis B in patients with a history of hepatitis B virus replication and in combination with Zidovudine for the treatment of HIV in adults and children over 3 months of age.3. How to use Lamozit
Treatment of hepatitis B at an adult dose of 100 mg/day. Children over 12 years of age use a weight-based dose of 3mg/kg. The maximum dose is 100mg/day. In cases of renal failure, the dose should be adjusted to be reasonable. Treatment of HIV in combination with Zidovudine: Adults use a dose of 150mg / time x 2 times / day, when using Zidovudine 600mg / day divided into 2-3 times. Children use dose 4mg/kg/time x 2 times/day. The maximum dose is 300mg/day when combined with Zidovudin 360 - 720mg/day in divided doses. Dose reduction should be considered in patients with renal impairment when the ClCr index is < 30 mL/min. Lamozit should not be used in patients with hypersensitivity to any of its ingredients.
4. Side effects of Lamozit
Some of the side effects that may occur when taking the drug include headache, irritability, fatigue, gastrointestinal disturbances, cramps, epigastric pain, insomnia, fever, cough, runny nose, and rash.5. Some notes when using Lamozit
Care should be taken to use the drug for sensitive subjects such as people with severe renal impairment, pregnant or lactating women. When patients have signs of pancreatitis, periodic clinical monitoring and liver function tests should be performed. In summary, Lamozit is a prescription drug for the treatment of chronic hepatitis B in patients with a history of hepatitis B virus replication and in combination with Zidovudine for the treatment of HIV in adults and children over 3 months of age. To ensure the safety of your health and maximize the effectiveness of treatment, you need to take the medicine exactly as directed by your doctor.
