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Kagasdine drug is used in cases such as gastric ulcer, duodenal ulcer, gastroesophageal reflux disease. The drug has the effect of reducing acid secretion of gastric juice, reducing factors that attack the lining of the stomach and duodenum. To understand more about the uses, usage and notes when using Kagasdine, please read the article below.
1. Uses of Kagasdine
Kagasdine 20mg drug with the main ingredient is Omeprazole 20mg, made in the form of capsules. Omeprazole is a proton pump inhibitor (PPI) drug, which is a reversible inhibitor of the hydro-potassium adenosine triphosphatase enzyme system (also known as the proton pump H + K + ATPase) in the parietal cells of the stomach. Thus reducing gastric acid secretion.
The drug is fast acting, long lasting but reversible. Omeprazole has no effect on acetylcholine receptors or on histamine receptors. The drug reaches its maximum effect after 4 days of taking the drug.
2. Indications and contraindications of the drug Kagasdine
Kagasdine is indicated in the following cases:
Gastric ulcer - duodenal ulcer; Reflux of gastric juice and esophagus; Zollinger-Ellison syndrome. Contraindications of the drug Kagasdine include:
Do not use for people who are sensitive to the drug and other components of the drug; Use with caution in pregnant and lactating women. 3. Dosage and how to use Kagasdine 20mg How to use: Oral medicine. Drink 30 minutes before meals or use at night before going to bed. The drug is used before meals because the parietal cells of the stomach will increase gastric acid secretion when eating, you take it first to reduce the secretion of gastric acid, reduce the impact of gastric acid on the ulcer site.
Dosage: Usual adult dose:
Duodenal ulcer: Take 1 tablet (20mg) x 1 time a day, continuously for 2-4 weeks. Severe cases or bleeding can take 2 tablets (40mg) and 1 time / day, used continuously for 4 weeks. Stomach ulcer, reflux esophagitis: Take 1 tablet (20mg) per day, take the drug continuously for 4 - 8 weeks. Severe cases can take 2 tablets of Kagasdine (40mg) x 1 time / day, taking the drug continuously for 8 weeks. Zolinger-Ellison syndrome: Initial dose with high dose 3 tablets (60mg) x 1 time / day. Maintenance dose: Take 1-6 tablets (20-120mg)/day, depending on response and clinical manifestations. Note, with doses greater than 80mg/day, the drug should be divided into 2 doses during the day. 4. Side effects of the drug Kagasdine When using Kagasdine you may experience undesirable effects as follows:
Common: Headache, drowsiness, feeling dizzy, nausea, vomiting, sore throat, constipation ; Uncommon: Insomnia or trouble sleeping, fatigue, urticaria, pruritus, skin rash. These effects are usually mild and reversible. Rare: Anaphylactic reaction, this is a serious reaction requiring immediate medical attention. Other side effects: Prolonged heartburn, osteoporosis, chest discomfort, choking, weight loss... 5. Notes when using Kagasdine 20mg Some notes when using Kagasdine include:
Before using use the drug you need to carefully read the instructions for use and avoid using it when you are allergic to the drug; Before giving Omeprazole to patients with peptic ulcers, the possibility of malignancy in the gastrointestinal tract must be excluded because the drug may mask symptoms and delay diagnosis; The drug can cause unwanted effects on the nervous system such as headache, drowsiness, dizziness, so be careful when using for drivers and operating machines; For pregnant women because there are no specific studies on this issue, it is best not to use; This is a drug that reduces gastric acid secretion, so if used for a long time, it can make the amount of secretions not enough for digestion and pathogenic microorganisms. Use only as indicated in a reasonable period of time, avoid abuse; Lactation: There are no specific studies, so it's best not to use it for breastfeeding women; The maximum dose is a single oral dose of 160 mg, a single intravenous dose of up to 80 mg, a 1-day intravenous dose of approximately 200 mg, and a 3-day intravenous dose of 520 mg is still tolerated. Avoid overdose; If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Note: Do not take double the prescribed dose. Possible drug interactions are as follows: Omeprazole may increase blood levels of Cyclosporin; increase the effect of anti-HP drugs; inhibit the metabolism of drugs metabolized by the enzyme system in cytochrome P450 of the liver and the drug can increase the concentration of substances such as Diazepam, Phenytoin and Warfarin in the blood; Omeprazol increases the anticoagulant effect of Dicoumarol... Store the drug in a cool place, the temperature is below 30 degrees Celsius, avoid direct light and keep out of reach of children. Above is information about the uses, uses and precautions of Kagasdine. If you have any questions or unusual symptoms while taking the drug, consult your doctor or pharmacist.
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