Uses of Ibaganin

This is an automatically translated article.

1. What is Ibaganin?

What is Ibaganin? Ibaganin oral solution contains the main ingredient is Arginin hydrochloride with a concentration of 1g/5ml. Ibaganin medicine also contains a system of excipients including: sodium citrate, citric acid, aspartame, sodium benzoate, orange essential oil, ethanol 96%, tartrazine, purified water.
Agrinin is an important substance in the urea cycle, this active ingredient has the ability to restore Agrinin levels in the blood and prevent protein catabolism complications when patients have a deficiency of enzymes such as: N- Acetylglutamate synthetase, Argininosuccinate Synthetase...
In the Urea cycle, Ammonia is converted into less toxic products and easily excreted in the urine, so Agrinin has the effect of treating hyperammonemia, protecting liver cells effectively. . In addition, Agrinin also stimulates the pituitary gland and pancreas, thereby releasing growth hormones, Glucagon and Insulin, changing blood glucose levels. In fact, the amount of glucose released from the liver is closely related to the concentration of amino acids absorbed in the human body.

2. Indications - contraindications of the drug Ibaganin

Indications of Ibaganin:
Ibaganin is indicated for use in liver dysfunction, supportive treatment of dyspepsia; Congenital hyperammonemia; For patients with impaired enzymes Ornithine Carbamyl Transferase and Carbamylphosphate Synthetase; People with Citrulin blood or Arginosuccinicuria; Enhance exercise capacity in patients with stable cardiovascular disease. Nutritional supplementation for patients with Urea cycle disorders such as type 1 and type 2 hyperammonemia, citrulinemia, arginosuccinicuria, N-acetyl glutamate synthetase deficiency. Contraindications of the drug Ibaganin:
Hypersensitivity to the components of Ibaganin; Patients with plasma organic acids lead to hyperammonemia; People with urea cycle disorder due to deficiency of the enzyme Arginase.

3. Dosage - How to use the drug Ibaganin

Treatment of maintenance Ibaganin in patients with carbamylphosphate synthetase deficiency, ornithine carbamyl transferase deficiency:
Infants or children from 1-18 months of age: Ibaganin dose 100mg/kg/day, every day using 3 - 4 times; Ibaganin maintenance therapy in patients with citrulinemia, Arginosuccinicuria;
Infants and children from 1 - 18 months old: Use Ibaganin dose 175mg/kg/time x 3 - 4 times per day; Take Ibaganin with food and adjust the dose according to the child's response. Patients with dyspeptic disorders:
Adults: Ibaganin dose 3 - 6 ampoules per day, corresponding to each taking 1-2 ampoules or 1-2 teaspoons, taken before 3 main meals (or 1 scoop) Ibaganin soup at noon and in the evening). Children: 1 ampoule of Ibaganin or 1 teaspoon x 2 to 3 times/day. Use of Ibaganin drug to enhance exercise capacity in people with stable cardiovascular disease:
Use Ibaganin for adults, take 6-21 ampoules/day, divided into several times a day, each use does not more than 8 ampoules of Ibaganin. Nutritional supplementation for Urea cycle disorders:
Adults take 3 - 20 ampoules of Ibaganin per day, depending on the patient's response; Congenital hyperammonemia: Ibaganin dose is from 250 - 500 mg/kg/day, respectively:
Infants: 1 - 5 ampoules of Ibaganin or 1 to 5 teaspoons/day, dilute Ibaganin with water or in a bottle milk; Children: 5-10 ampoules of Ibaganin or 5 to 10 teaspoons/day. Take Ibaganin with a little water. Ibaganin can be mixed with a sufficient amount of water and used before the main meal, except for some special cases where Ibaganin must be taken with food. Patients need to strictly follow the doctor's instructions on the dosage of Ibaganin. Do not arbitrarily stop taking Ibaganin for the best treatment effect.

4. Side effects of the drug Ibaganin

Unwanted effects that may occur when using Ibaganin 1g/5ml include:
Common: Ibaganin causes frostbite, headache, nausea, hyperthermia, local venous irritation...; Rare side effects of Ibaganin: Pain, edema, thrombocytopenia, anaphylactic reactions...; In addition, Ibaganin drug can also cause symptoms with an indeterminate frequency such as: hypotension, abdominal muscle spasms, abdominal distention, release of growth hormone, prolactin, insulin, increase in serum creatinine..
When you see unusual phenomena, stop taking Ibaganin and tell your doctor about the symptoms you have experienced.

5. Notes when using and storing Ibaganin

Do not use Ibaganin for patients with a history of allergic disease; Ibaganin should be used with caution in patients with renal failure, because Ibaganin can cause hyperkalemia; Ibaganin contains a large amount of nitrogen, so before using Ibaganin, it is necessary to evaluate kidney function for its ability to respond to high concentrations of nitrogen. Subjects after myocardial infarction did not use Ibaganin drug; Excipients contain Phenylalanin, so Ibaganin should be used with caution in people with phenylketonuria. Tartrazine in the excipients can cause allergies, so when using Ibaganin, caution should be exercised. Pregnancy: There have been no reports to prove the safety of Ibaganin, so it is not recommended to use it in pregnant women. Breastfeeding women: It is necessary to weigh the benefits and risks of Ibaganin, if using Ibaganin, breast-feeding must be stopped to ensure safety for the baby. Overdosage of Ibaganin can cause metabolic acidosis, cerebral edema, and worse, death. Therefore, patients should prevent with antihistamines if allergies occur, when not self-managed, immediately go to the nearest medical facility for medical support. Store Ibaganin medicine in a dry place, away from moisture and direct light, out of reach of children, avoid the risk of children swallowing it, and the storage temperature should be maintained below 30 degrees Celsius.
Ibaganin oral solution contains ingredients. is Arginin hydrochloride with a concentration of 1g/5ml. Medicines are effective in treating many diseases. Patients need to strictly follow the doctor's instructions on dosage and use to get the most effective treatment and limit unwanted side effects.
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