This is an automatically translated article.
Hypevas 10 belongs to the group of cardiovascular drugs with pravastatin as the main ingredient, indicated for patients with primary hypercholesterolemia or dyslipidemia. In particular, the drug Hypevas 10 also has the ability to prevent cardiovascular death or prevent vascular accidents. Medicines are sold by prescription and are used only when prescribed by a qualified doctor or pharmacist.
1. What is Hypevas 10?
What is Hypevas 10 drug? Hypevas 10 belongs to the group of cardiovascular drugs, with the main active ingredient being Pravastatin sodium 10 mg, indicated for patients with primary hypercholesterolemia or dyslipidemia. Hypevas 10 is researched and developed by Ha Tay Pharmaceutical Joint Stock Company. Ingredients in 1 tablet include Pravastatin sodium 10mg and excipients just enough. The product is prepared in tablet form, packing box of 6 blisters x 10 tablets. This is a prescription drug, so when using it, you must follow the doctor's prescription.
2. The effect of the drug Hypevas 10
Hypevas 10 drug has the main ingredient pravastatin sodium - this is an active ingredient that competitively inhibits 3-hydroxy-3-Methylglutaryl-coenzyme (HMG -CoA) reductase by preventing HMG - CoA metabolism. into Mevalonate, while preventing the body from biosynthesis of cholesterol, thereby stimulating the synthesis of LDL receptors.
From the mechanism of Pravastatin sodium, the effects of Hypevas 10 are:
Reduces cholesterol content in liver cells. Increased transport of LDL (Low Density Lipoprotein) from the blood. Decreased TG (Triglyceride), VLDL (Very Low Density Lipoprotein) and increased HDL-C (HDL cholesterol). Reducing bad lipids such as: LDL-cholesterol, Apolipoprotein B, VLDL-cholesterol, Total cholesterol, Triglycerides Stimulates the production of good lipids such as: Apolipoprotein A, HDL-cholesterol.
3. Indications and contraindications for the drug Hypevas 10
3.1 Indications Hypevas 10 is indicated for the following cases:
Treatment of hypercholesterolemia: Primary hypercholesterolemia, mixed dyslipidemia. Immunosuppressive treatment after organ transplantation for organ transplant patients. Prevention of moderate and severe hypercholesterolemia or high risk of stroke. Prevention of recurrent unstable angina, myocardial infarction in people with a history of cardiovascular disease. 3.2 Contraindications Hypevas 10 is not recommended to be used in cases:
People with hypersensitivity to substances capable of inhibiting HMG - CoA reductase or to the ingredients contained in the drug. Women who are pregnant or breastfeeding. Transaminase levels in the serum are persistently elevated for unknown reasons. People with liver disease. Can be used by children under 8 years of age who have not been studied
4. Usage and dosage of Hypevas 10
4.1 How to use Hypevas 10 is a prescription drug, made in tablet form and taken orally. According to recommendations from the manufacturer and doctors, the drug should be taken on an empty stomach or during meals with plenty of water. The best time of day to take the drug is in the evening, because this is the time when the liver synthesizes cholesterol mainly at night. Note that to be good for the treatment process, patients should limit their intake of cholesterol-containing foods. 4.2 Dosage Usually the amount used will be based on age, weight and severity of the disease.
Children under 18 years old:
Children 8-13 years old: Take 1-2 tablets/day. Children 14-18 years old: Take 1 - 4 tablets/day. Adults:
Cardiovascular disease prevention: Take the initial and maintenance dose of 40mg/day. Hypercholesterolemia: Take 10-40mg/day, 30 minutes before bedtime. If the body tolerates well, take it every 4 weeks. After organ transplant: Initial dose is 20-40mg/day, however, lipid index should be monitored. Old people
Same as above, but if you have rhabdomyolysis, absolutely do not arbitrarily use it.
Patients with liver and kidney failure
Initial dose 10mg/day or may increase the dose if indicated.
5. Drug interactions
Interactions when combining certain drugs together are inevitable. Therefore, you should note that Hypevas 10 should not be used together with some of the following drugs:
Bile acid resin (Colestipol, Cholestyramine), if used at the same time, it is best to take Hypevas 10 1 - 4 hours before , then drink the plastic to reduce the possibility of interaction. Fusidic acid: May cause muscle weakness or pain. Cyclosporin: 4-fold increased exposure to pravastatin. Warfarin and other oral anticoagulants: Increases the effect of Warfarin and reduces the effect of Hypevas 10. High-dose Niacin (> 1g/day) and Colchicine: Muscle damage. Medicines to treat HIV and hepatitis C virus (HCV): There is an increased risk of muscle damage, kidney failure and death.
6. How to deal with missed dose or overdose?
In case you miss a dose, you need to take it as soon as possible, but if it is almost time for the next dose, skip the missed dose and take the next dose. Do not take a double dose to make up for the missed dose.
On the contrary, if you take an overdose, you need to stop drinking when abnormal symptoms appear and immediately go to the nearest medical facility for the fastest treatment. Usually, an overdose does not show any special symptoms and there are no life-threatening complications.
7. Undesirable effects
Side effects occur with western medicine is inevitable. Here are some possible side effects namely:
Blurred vision, dizziness (uncommon) Abdominal pain, heartburn, nausea, defecation, flatulence, constipation,... Headache, dizziness, trouble sleeping, sweating,... Nocturia, urge to urinate, ... Urticaria, tingling, redness,...
8. Note when using drugs
Hypevas 10 is sold by prescription and only when prescribed by a doctor. Some notes when taking drugs you need to pay attention to are as follows:
Before starting treatment with drugs containing Pravastatin, you need to do a liver enzyme test. The drug is not recommended for use in pregnant and lactating women because it can affect the fetus and young child. Some side effects such as dizziness, headache, nervous disorders. So do not use when operating, participating in traffic. Use caution in patients with liver disease and heavy alcoholism. Children under 8 years of age have not been proven to be effective in treatment as well as side effects, so they should not be used. Do not use Hypevas 10 when the cholesterol level in the blood is too high due to high HDL-cholesterol. In some special cases, creatine kinase (CK) should be monitored. Do not use Hypevas 10 for people with congenital galactosemia, glucose malabsorption syndrome or lactase deficiency. Store the medicine at a suitable temperature (30 degrees). Hypevas 10 belongs to the group of cardiovascular drugs with the main ingredient pravastatin, indicated for patients with primary hypercholesterolemia or dyslipidemia. In particular, the drug Hypevas 10 also has the ability to prevent cardiovascular death or prevent vascular accidents. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
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