Uses of Hoebeprosone

This is an automatically translated article.

1. What is Hoebeprosone?

Hoebeprosone medicine is a topical drug containing the main ingredient is Betamethasone dipropionate, concentration 0.064%, packaged in 15g tubes. The drug is manufactured by HOE Pharm Sdn Bhd - Malaysia and circulated in Vietnam with registration number VN-13175-11.
Betamethasone is a synthetic corticosteroid with very strong Glucocorticoid effect (very strong anti-inflammatory effect) with negligible Mineralocorticoid effect (salt retention effect). When using Hoebeprosone topically, the active ingredient Betamethasone is effective in the treatment of corticosteroid-responsive skin diseases thanks to its anti-inflammatory, anti-allergic, and vasoconstrictor effects.
Betamethasone is absorbed quite well when applied topically, especially when the bandage is closed or when the skin is damaged, it will increase the ability to absorb Betamethasone through the skin, even when a large enough amount of Betamethasone is absorbed, it will have a full effect. Dear. After absorption through the skin, active substance Betamethasone will be metabolized mainly in the liver and excreted by the kidneys.

2. Uses of the drug Hoebeprosone

Hoebeprosone is used to treat inflammatory skin diseases such as: eczema, especially eczema in children, hypersensitivity dermatitis, contact dermatitis, neurodermatitis, psoriasis, impetigo.

3. Contraindications of Hoebeprosone

Hoebeprosone drug is contraindicated in the following cases:
Hoebeprosone is contraindicated in patients with hypersensitivity to Betamethasone Dipropionate or other corticosteroids and any component of Hoebeprosone. Contraindicated to use Hoebeprosone drug in skin lesions caused by bacteria, viruses, fungi, parasites on a large area of ​​skin, skin lesions with ulcers, acne.

4. Dosage and how to take Hoebeprosone

Hoebeprosone is used topically by applying a thin layer to the affected area 1-2 times a day as directed by your doctor or pharmacist.
In case of overdose of Hoebeprosone: the effect of increased corticosteroids usually does not appear soon unless the patient takes too high a dose and continuously. Systemic effects due to Hoebeprosone overdose may be encountered such as sodium and water retention, increased appetite, calcium and phosphorus mobilization leading to osteoporosis, hyperglycemia...
In case of acute Hoebeprosone overdose, Patients should be monitored for serum and urine electrolytes. Pay special attention to the sodium and potassium balance. In case of chronic Hoebeprosone intoxication, it is necessary to gradually stop the drug and treat the electrolyte imbalance (if necessary).

5. Drug interactions of Hoebeprosone

Betamethasone is very easily absorbed when used locally and for systemic effects, so using Hoebeprosone can lead to:
Hoebeprosone drug increases the risk of hepatotoxicity if used with high doses of Paracetamol or prolonged use prolongation; Betamethasone has the potential to increase blood glucose levels, so it may be necessary to adjust the dose of oral antidiabetic drugs or to adjust the dose of insulin injections; Betamethasone increases the possibility of cardiac arrhythmias or the occurrence of digitalis toxicity, accompanied by hypokalemia when co-administered with digitalis glycosides; Hoebeprosone may increase or decrease the anticoagulant effect of Coumarin-type anticoagulants, so a dose adjustment of this drug may be necessary; Betamethasone may increase blood levels of salicylates; Hoebeprosone in combination with non-steroidal anti-inflammatory drugs or alcohol may increase the severity of peptic ulcer disease; Tricyclic antidepressants have the potential to increase corticosteroid-induced psychosis; Phenobarbital, Phenytoin, Rifampicin, Ephedrin... can increase metabolism and reduce the therapeutic effect of Hoebeprosone; Estrogen can alter the metabolism and protein binding of Betamethasone, thereby reducing the clearance, increasing the therapeutic effect and toxicity of Hoebeprosone; Aspirin should be used with caution in combination with betamethasone in patients with hypoprothrombinemia. Using Hoebeprosone for pregnant women should be cautious, weighing the benefits and risks of the drug to the mother and the fetus; For nursing women, avoid applying Hoebeprosone directly to the nursing breast.

6. Hoebeprosone side effects

Undesirable effects of Hoebeprosone drug related to dose and duration of treatment:
Local side effects of Hoebeprosone: burning sensation, itching, irritation, folliculitis, hair growth, rash acne, hypopigmentation, secondary infection, skin atrophy, striae..., more rarely allergic dermatitis, urticaria, angioedema. Systemic side effects of Hoebeprosone: Effects of Hoebeprosone on metabolism: common loss of potassium, sodium retention, water retention; Effects of Hoebeprosone on the endocrine system: menstrual irregularities, Cushing's syndrome, growth inhibition of the fetus and young child, decreased glucose tolerance; Effects of Hoebeprosone on skeletal muscle: causing muscle weakness, loss of muscle mass, osteoporosis; Effects of Hoebeprosone on the nervous system: euphoria, mood swings, depression, insomnia, benign intracranial hypertension; Effects of the drug on the eyes: cataracts, glaucoma; Effects of Hoebeprosone on the digestive system: gastric ulcer, gastrointestinal bleeding, pancreatitis, abdominal distension, esophageal ulcer.

7. Be careful when using Hoebeprosone

Discontinue use of Hoebeprosone if irritation, hypersensitivity or other unusual reactions appear, at which time appropriate therapy should be instituted; Topical corticosteroids can be absorbed causing systemic effects, so careful monitoring of patients is necessary during prolonged Hoebeprosone treatment, when using Hoebeprosone on a large scale, when using the graft technique, and when using Hoebeprosone. for children; The safety of Hoebeprosone during pregnancy and lactation has not been established. Therefore, Hoebeprosone should not be used in pregnant and lactating women. Hoebeprosone is a topical medication that contains betamethasone dipropionate as the main ingredient. Hoebeprosone medicine is used to treat inflammatory skin diseases such as: eczema, especially eczema in children, hypersensitivity dermatitis, contact dermatitis, neurodermatitis, psoriasis, impetigo. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to strictly follow the instructions of the doctor, professional pharmacist.
Follow Vinmec International General Hospital website to get more health, nutrition and beauty information to protect the health of yourself and your loved ones in your family.

Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.