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Hasanclar 500mg is an antibiotic with the ability to inhibit the growth of bacteria, used to treat mild to moderate infections caused by susceptible bacteria.1. What is Hasanclar 500mg?
Hasanclar 500mg medicine contains the main ingredient is Clarithromycin, belongs to the new generation Macrolide antibiotic.
Clarithromycin is usually only able to inhibit the growth of bacteria, kill bacteria at high doses or against very sensitive strains of bacteria. The structural change has helped to expand the antibacterial spectrum, reducing side effects on the digestive system.
Hasanclar 500mg is highly effective against gram-positive and gram-negative, aerobic and anaerobic bacteria, including: Streptococcus, staphylococcus, Listeria monocytogenes, Haemophilus influenzae, Moraxella (Branhamella) catarrhalis, Helicobacter pylori, Mycoplasma pneumoniae...
Hasanclar is rapidly and well absorbed from the gastrointestinal tract after oral administration. Food in the stomach does not affect the effect of the drug. The drug is extensively metabolised in the liver and excreted mainly in the faeces via the bile. The remainder is excreted in the urine. Approximately 20-30% of the 250 mg and 500 mg doses, respectively, are excreted unchanged by this route.
2. Indications of Hasanclar 500mg
Hasanclar 500mg is generally indicated for the treatment of adults and children 12 years of age and older. It is used to treat mild to moderate infections caused by susceptible bacteria. Specifically:
Lower respiratory tract infections: Exacerbation of chronic bronchitis, community-acquired pneumonia; Upper respiratory tract infections: Acute sinusitis, acute pharyngitis, tonsillitis, otitis media; Community respiratory tract infections; Skin and soft tissue infections; Immunocompromised HIV-infected patients cause opportunistic infections.
3. Contraindications of Hasaclar
Hasaclar 500mg is contraindicated in the following cases:
Patients are sensitive to Macrolide antibiotics; Patients with hypokalemia ; Patients with renal failure combined with liver failure; Patients with creatinine clearance <30ml/min.
4. Notes when using Hasaclar
Do not combine Hasaclar 500mg with Ergotamine or Dihydroergotamine because it can cause poisoning; Hasaclar is not used concurrently with Cisaprid, Astemizol, Pimozide and Terfenadine because it can cause cardiac arrhythmias; Hasaclar is not used concurrently with HMG-CoA inhibitors (Statins group) because it may increase the risk of myopathy, rhabdomyolysis; Do not use Hasaclar medicine for patients who are taking Colchicine ; Long-term and repeated Hasanlar 500mg treatment may cause superinfection with susceptible fungi or bacteria; In some patients, H. pylori may become resistant to Hasaclar; Risk of hypoglycemia when used in combination with antidiabetic drugs; Concomitant use of Hasaclar 500mg with the anticoagulant Warfarin increases the risk of major bleeding, INR and prothrombin time; The drug can cause dizziness, loss of balance, loss of orientation, so be careful when taking the drug if you have to drive, operate machinery,...; Pregnant and lactating women need a doctor's prescription and supervision when taking the drug.
5. Dosage and how to use Hasanclar 500mg
Usage:
Hasanclar is stable in acidic environments and well absorbed with or without food. The medicine can be taken before or after a meal. Dosage in respiratory tract, skin and soft tissue infections:
Adults and children > 12 years: Initial dose: 1⁄2 tablets x 2 times/day for 7 days; Severe infections: 1 tablet x 2 times/day and can last up to 14 days; Patients with severe renal impairment (creatinine clearance less than 30 ml/min): 1⁄2 usual dose. Children under 12 years: Initial dose: 7.5mg/kg body weight x 2 times/day, for 7-10 days. Maximum dose: 1 tablet (500mg) x 2 times/day. Dosage in community-acquired pneumonia:
Initial dose: 15mg/kg body weight x 12 hours/time. Dosage in bacilli (Mycobacterium infection):
Adults: Initial dose: 1 tablet x 2 times/day for 7 days; Children: Initial dose is 7.5mg/kg body weight x 2 times/day. The maximum dose is 500mg/day.
6. Side effects of the drug Hasanclar 500mg
When using Hasanclar 500mg, patients may experience some unwanted effects as follows:
Common:
Vomiting, abdominal pain, indigestion, diarrhea; Dull headache; In pediatric patients, rash and itching may occur. Rare:
Anaphylactic reactions: Rash, urticaria, Stevens - Johnson syndrome; Inflammation of the oral mucosa, taste disturbances; High doses cause hearing loss; Anxiety, dizziness, lightheadedness, psychosis; Increased liver enzymes , jaundice, yellow eyes; Fever, swollen glands, body aches. Hasanclar 500mg is a medicine used to treat some diseases caused by bacteria. In addition to the bactericidal effect of the drug, it also causes many unwanted side effects, so patients need to follow the doctor's instructions to achieve optimal results.
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