Uses of Granisetron Transdermal System (Sancuso®)

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Sancuso® is a serotonin-3 (5-HT3) receptor antagonist, which is effective in preventing and controlling nausea and vomiting. Find out more information about the drug through the article below.

1. What is Sancuso®?


Sancuso® has Granisetron as the main ingredient, in the form of a patch.
Granisetron Transdermal System is a serotonin-3 (5-HT3) receptor antagonist. 5-HT3 receptors found in nerve areas in the brain and stomach can trigger the pharyngeal reflex. Granisetron blocks this reflex and helps prevent and control nausea and vomiting.

2. Uses of the drug Sancuso®


Sancuso® is used for patients taking anti-cancer drugs who experience severe nausea and vomiting as a side effect.

3. Usage and dosage of Granisetron


How to use: Apply Sancuso on the arm before, during and after cancer treatment. The application area should be free of lotions, moisturizers, powders or other skin products. Do not apply the patch to freshly shaved or red or broken skin.
Dosage: Apply a patch 24 - 48 hours before cancer treatment. Keep this patch for at least 24 hours after the last dose of cancer treatment that week. The patch has stickiness to stay on for up to 7 days. Consult your doctor to find out how long you wear the patch

4. Possible side effects when taking Sancuso®


A common Sancuso® side effect that can be experienced is constipation. To limit constipation, patients should increase fiber in their diet, drink 8 to 10 glasses of water a day and increase activity. If you have not had a bowel movement for 2-3 days, you should contact your doctor for advice to help you improve this condition.
There are also a few less common side effects including: intestinal obstruction, serotonin syndrome, skin rash...

5. Things to keep in mind when taking Sancuso®


Only remove the Granisetron patch from the pouch when you are ready to use it, preferably just before use. Do not subdivide the patch into smaller pieces.
Wash your hands immediately after applying the patch. If the patch starts to peel off you can use medical tape around the edges of the patch to keep it in place. Do not wrap or bandage the entire patch..
When you remove the patch, remove it slowly and fold the patch in half, with the medication side inside. Make sure that children and pets do not come into contact with the patch.
After removing the patch, if there is still glue on the skin, wash it off with soap and water (avoid using alcohol to remove the adhesive). The skin area after removing the patch may be slightly red. If the condition does not go away in 3 days, call your doctor.
Do not use heating pads or heating lamps near the patch area, as prolonged exposure to heat can increase drug levels in the body.
Tell your doctor about all medications and supplements you are taking, history of whether or not you have an allergic reaction to adhesive tape or medical tape.
Above is some information about the use of Sancuso®, if you have any questions, you should consult directly with a pharmacist or doctor before using the drug.


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Reference source: oncolink.org
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