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Espacox is indicated in the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis,... What does Espacox do, how to use it, let's find out the uses of Espacox through this article. write below.
1. What is Espacox?
Each capsule contains
Active ingredient: Celecoxib 200 mg.
Excipients: Lactose monohydrate, sodium laurilsulfate, povidone, croscarmelose sodium, vegetable grade anhydrous colloidal silicon magnesium stearate, titanium dioxide (CI=77891, E-171), yellow iron oxide (E-172, CI=77492), gelatin
Packing: Box of 3 blisters x 10 capsules
Manufacturer: Laboratorios Normon, S.A - Spain
2. Uses of the drug Espacox
Indications:
Symptomatic treatment of osteoarthritis (OA) and rheumatoid arthritis (RA). Alleviation of signs and symptoms of juvenile idiopathic arthritis (JIA) in patients 2 years of age and older weighing at least 10 kg. Alleviate the signs and symptoms of ankylosing spondylitis. Management of acute pain. Treatment of primary dysmenorrhea. Dosage- Method of administration
Because the cardiovascular risk of the drug can increase with dose and duration of use, the drug should be used for the shortest possible time with the lowest effective daily dose
Osteoarthritis: The recommended dose is 200mg, taken once a day or divided into 2 times. For patients without satisfactory symptom relief, increasing the dose to 200 mg twice daily may improve the effectiveness of the treatment of rheumatoid arthritis: The recommended starting dose is 200 mg daily in 2 divided doses. (This dose cannot be used with this product, there are other products with 100mg strength). If necessary, the dose may then be increased to 200mg twice daily. Ankylosing spondylitis: The recommended daily dose is 200mg, once daily or in 2 divided doses. Increasing the dose to 400mg, orally once a day or in two divided doses may help improve the effectiveness of treatment. The maximum recommended daily dose is 400mg, for all indications. If therapeutic benefit does not increase after 2 weeks, other treatment options should be considered. Oral medication, which can be taken with or without meals. Tablets should be swallowed whole with water
3. Side effects of the drug Espacox 200mg
Hypertension, Angina, Myocardial infarction, Sinusitis, Shortness of breath, Upper respiratory tract infection, Urinary tract infection, Insomnia, Dizziness, Increased muscle tone, Abdominal pain, Difficult diarrhea Digestive, Flatulence, Rash, Itching, Allergies
4. Notes when using Espacox 200mg
Contraindications
Celecoxib is contraindicated for:
Patients with a history of hypersensitivity to celecoxib or any component of the drug. Patients with a history of hypersensitivity to sulfonamides. Patients with a history of asthma, urticaria, or allergic-type reactions after taking UI acetylsalicylic acid (ASA [aspirin]) or other nonsteroidal anti-inflammatory drugs (NSAIDs), including specific inhibitors other cyclooxygenase-2 (COX-2). Treatment of pain during coronary artery bypass grafting (CABG) Precautions while using Espacox 200mg
Hypersensitivity to any component of the drug Known hypersensitivity to sulfonamides Active gastric ulcer or Gastrointestinal bleeding Patients with history of bronchial asthma, acute rhinitis, nasal polyps, angioedema, urticaria or other allergic-type reactions Pregnant women or women of childbearing age except when using an effective method of contraception Lactating women Severe liver dysfunction Patients with severe renal impairment (creatinine clearance < 30ml/min) Inflammatory bowel disease Congestive heart failure Confirmed ischemic heart disease conditions, peripheral artery disease and cerebrovascular disease Precautions/Warnings
Driving and using machines
No studies on the effects of celecoxib on the ability to drive and use machines have been performed but are based on the pharmacodynamic properties and a general description of the safety of the drug, which can be considered as unaffected.
Pregnancy
Fertility:
Based on the drug's mechanism of action, the use of NSAIDs, including celecoxib, may delay or prevent ovulation, leading to reversible infertility in some women. Women who have difficulty conceiving or are undergoing treatment for infertility should consider discontinuing NSAIDs, including celecoxib.
Pregnant women:
There are no studies in pregnant women. Some animal studies have shown reproductive toxicity. There are no comparable data in humans.
Celecoxib, as with other prostaglandin synthesis inhibitors, can cause uterine muscle impotence and premature aortic duct damage, so celecoxib should be avoided during the third trimester of pregnancy.
Celecoxib should be used during pregnancy only if the potential benefit to the mother outweighs the potential risk to the fetus.
Lactation:
Studies in rats have shown that celecoxib is excreted in milk at concentrations comparable to those in plasma. In lactating women receiving celecoxib, very little celecoxib is passed into breast milk. Because of the potential adverse effects of celecoxib in the nursing infant, depending on the desired benefit to the mother, discontinuation or discontinuation of breastfeeding should be considered.
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