This is an automatically translated article.
Esafosfina is a group of drugs that regulate water and electrolytes and require Acid-Base containing the main ingredients such as the sodium salt of Fructose-1, 6-diphosphate. Esafosfina 5g/50ml is indicated for subjects with myocardial infarction, shock treatment and some cases of severe ischemia in the lower extremities.
1. Effects of the drug Esafosfina
Esafosfina drug includes the sodium salt components of Fructose-1, 6-diphosphate (FdP) with a content of 5g, equivalent to 3.75g of fructose-1,6-diphosphoric acid. Esafosfina is prepared in the form of lyophilized powder mixed with intravenous solution, each box of Esafosfina contains 1 glass vial of drug powder, 1 vial of solvent with 50ml distilled water for injection and 1 set of infusion kits.
Therefore, the drug Esafosfina is also known as Esafosfina 5g/50ml
Studies show that FdP - a main ingredient in the drug Esafosfina:
Has the ability to protect red blood cells from hemolysis and at the same time prevent the formation of erythrocytes. formation of toxic oxygen radicals in neutrophils. Will counteract the toxicity of potassium on atrial contraction thereby helping to improve cardiac arrest. Can block the breakdown of cardiac ATP and creatine phosphate in ischemic myocardium, protect liver and kidney from ischemic damage. The drug is protective against shock caused by trauma or blood loss. Promotes the resuscitation of the heart and lungs after the heart stops beating due to lack of oxygen. With the above uses, Esafosfina medicine 5g/50ml is often prescribed by doctors for the following cases:
Patients with myocardial infarction, in shock treatment and severe ischemic or ischemic cases. weight of the lower extremities. Hypophosphataemia is associated with a metabolic disorder (metabolic disease or severe burns requiring complete parenteral nutrition). In the setting of 2,3-diphosphoglycerate reduction following massive perfusion and during the use of extracorporeal circulation during cardiac surgery. Contraindications to the use of Esafosfina 5g/50ml for the following cases:
Patients with hypersensitivity to the components in the drug Esafosfina. Hyperphosphatemia. People with kidney failure.
2. Instructions on how to take Esafosfina
How to use: Dissolve 5g of Esafosfina 5g/50ml lyophilized powder with 50ml of packaged distilled water solution to form 10% solution. Rapid intravenous infusion at a rate of 10 ml/min.
Recommended dosage: 70-160mg/kg/time x 1 time/day.
Note: It is necessary to check for foreign particles in the formed solution before infusion, absolutely do not use Esafosfina if it is cloudy or precipitated. The inherent yellow color of the solution will not affect the potency of the drug.
3. Possible side effects when taking Esafosfina
Esafosfina has been well tolerated and no serious side effects have been reported. Rapid infusion may cause pain or irritation at the injection site. In cases where the infusion rate exceeds 10 ml/min, the patient may experience flushing, heart palpitations, and numbness in the fingers.
As with other intravenous solutions, some undesirable effects such as fever, infection at the injection site, phlebitis or phlebitis, intravenous injection may still occur. Tell your doctor right away if you experience any side effects of Esafosfina.
4. Notes when using Esafosfina
Be careful when using Esafosfina 5g/50ml for the following subjects:
Women who are pregnant and breastfeeding, will need to consult a doctor before deciding to use Esafosfina. In patients with creatinine clearance < 50 ml/min, blood phosphorus levels should be monitored. Interactions of Esafosfina drug is not compatible with other intravenous solutions containing solutes at pH 3.5 - 5.8 or with solutions with high calcium salt content in alkaline environment.
The above is important information about Esafosfina, before using, patients should carefully read the instructions for use to achieve better results. If you have any problems, contact your doctor for appropriate advice.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
