Uses of Enpovid Ad

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1. Uses of Enpovid Ad

Enpovid Ad is indicated for use in the following cases:
Prophylaxis and treatment of diseases caused by vitamin A deficiency such as dry eye disease, night blindness, people with primary biliary cirrhosis or chronic cholestatic liver disease . Vitamin A and vitamin D supplementation for children with rickets of growing age, pregnant and lactating women, and night blindness sufferers. Prevention and treatment of osteoporosis, including osteoporosis caused by the use of corticosteroids. Enpovid Ad is contraindicated in the following cases:
People who are sensitive or allergic to any of the ingredients of the drug. Hypercalcemia or vitamin D toxicity, metastatic calcification, impaired liver and kidney function. Patients with excess vitamin A, hypersensitivity to vitamin A or other ingredients in the preparation), lipid absorption disorders. Do not use Enpovid Ad for children under 6 years old.

2. How to use and dose Enpovid Ad

Enpovid Ad is used orally. During vitamin D treatment, adequate calcium intake from food or supplemental therapy is required. The doctor will prescribe a dose reduction when the signs or symptoms of the disease have improved and the biochemical tests are normal or cured.
Dosage of Enpovid Ad will depend on the purpose of treatment such as:
Prophylaxis of vitamin A deficiency:
For adults and children over 10 years old: 1 tablet each time. Drink once a day. For children from 6 to 10 years old: 1 tablet each time. Drink once every 2 days. Treatment of vitamin A deficiency:
For treatment of dry eye disease, immediately after diagnosis, 200,000 units of vitamin A must be given immediately, repeated oral doses of 200,000 units on the next day and after two weeks; Adults develop severe signs of dry eye that require treatment. When symptoms are mild, such as night blindness: use 1 - 2 tablets daily for at least 4 weeks or up to 5 tablets weekly. For people with primary biliary cirrhosis or chronic liver disease with cholestasis: Vitamin A is often given to patients because these people often have vitamin A deficiency.
Prevention of rickets
For adults, pregnant or lactating women: Take 1 tablet per day. For children 6 years and older: Take 1 tablet per day. Note: The above therapeutic dose is for reference only according to the manufacturer's instructions. The specific treatment dose depends on your health condition and the progress of the disease. For a specific and appropriate therapeutic dose, you need to consult your treating doctor or medical professional.
In case of overdose of vitamin A and vitamin D: You may experience fatigue, loss of appetite, nausea, exfoliative dermatitis, bone pain, brittle nails or hair, increased pressure. intracranial, increased calcium in the blood.
Measures to treat overdose due to Enpovid Ad overdose include:
Immediate gastric lavage or induce vomiting to avoid absorption of the drug into the bloodstream. Carry out repeated testing of calcium levels in the blood. If the calcium level in the blood is still high, the doctor may prescribe phosphate and corticosteroids, and use appropriate measures to increase urinary excretion. In case of missed dose: If you miss a dose, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time. Note that you should not use Enpovid Ad with double the prescribed dose.

3. Undesirable effects of the drug Enpovid Ad

3.1. For Vitamin A No dangerous undesirable effects have occurred when the recommended doses are used. Possible harmful side effects when taking high doses of vitamin A for a long time or taking a very high dose
Chronic poisoning: Long-term use of high doses of vitamin A can lead to poisoning vitamin A. The typical signs and symptoms of vitamin A poisoning are: Fatigue, irritability, loss of appetite, weight loss, vomiting, digestive disorders,... For children, the symptoms are Chronic poisoning includes increased intracranial pressure (stretch fontanelle), papilledema, tinnitus, visual disturbances, and painful swelling along the long bones. When vitamin A is stopped, the signs and symptoms also disappear, but bone growth may stop because the ends of the long bones have ossified too soon. Acute poison corn: Taking vitamin A in very high doses can lead to acute poisoning with the following signs: drowsiness, dizziness, dizziness, nausea, vomiting, irritability, headache, delirium and convulsions, diarrhea.... Signs and symptoms appear 6 to 24 hours after overdose. 3.2. For Vitamin D Using vitamin D at therapeutic doses not exceeding physiological needs is usually not toxic, but when treating high therapeutic doses or for a long time, symptoms of vitamin D overdose may occur. lead to hypervitaminosis D and very dangerous calcium toxicity. If you experience any of these side effects, you need to stop using the drug. You also need to inform your doctor about any unwanted effects you experience when using the drug.

4. Interactions of Enpovid Ad

Neomycin, Cholestyramine or Paraffin in liquid form reduce vitamin A absorption. Oral contraceptives may increase vitamin A plasma concentrations and have adverse effects on conception. Using the combination of Vitamin A and Isotretinoin can lead to a condition like an overdose of vitamin A. Vitamin D3-containing preparations should not be used concomitantly with cholestyramine or colestipol hydrochloride, as this may lead to decreased intestinal absorption of vitamin D3. Excessive use of mineral oil can interfere with the absorption of vitamin D3 in the intestines. Concomitant treatment of Enpovid Ad with a thiazide diuretic in patients with hypoparathyroidism may result in hypercalcemia. Concomitant use of vitamin D with phenobarbital or phenytoin is not recommended because these drugs may decrease plasma concentrations of 25 - hydroxyergocalciferol and 25 - hydroxy - cholecalciferol and increase the metabolism of vitamin D to inactive substances. Enpovid Ad should not be used concurrently with corticosteroids because corticosteroids interfere with the action of vitamin D. Concomitant use of Enpovid Ad with cardiac glycosides is not recommended. This is due to the increased toxicity of cardiac glycosides due to hypercalcemia, leading to arrhythmias.

5. Some notes when using Enpovid Ad

Before using Enpovid Ad you need to carefully read the instructions for use and refer to the information below.
Caution should be exercised when using other drugs that also contain vitamin A and vitamin D in combination. Pregnant women: Doses of more than 8,000 IU/day may cause teratogenic effects. People with sarcoidosis or hypoparathyroidism (which can cause increased sensitivity to vitamin D), impaired kidney function, heart disease, kidney stones, atherosclerosis. Do not overdose on Enpovid Ad unless directed by your doctor. In cases where long-term high doses are indicated, calcium levels in blood and urine should be regularly monitored to avoid overdose. Ability to drive and use machines: No component of Enpovid Ad affects the ability to operate machinery. Pregnancy: Do not take more than 8000 IU of vitamin A per day. Do not use Enpovid Ad in the first 3 months of pregnancy, high therapeutic doses can cause teratogenicity. Lactation: There are no specific reports on the effect of the drug on lactation. However, you should use caution when using Enpovid Ad only when prescribed by a treating doctor.

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