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Enoxaparin 60mg is used to prevent the effects of blood clots on the body. Therefore, the drug is used in cases where there is a high risk of blood clot formation.1. Uses of Enoxaparin 60mg
Enoxaparin 60 is an anticoagulant drug, this is a low molecular weight heparin, prepared as a solution for injection. The drug works to prevent and treat blood clots, which helps reduce the risk of an ischemic stroke or coronary heart disease. Enoxaparin helps blood flow by reducing the activity of proteins that cause blood to clot.
2. Indications and contraindications Enoxaparin 60mg Enoxaparin drug is indicated for use in the following cases:
Deep vein thrombosis has formed, with or without pulmonary embolism without serious clinical signs except in cases of pulmonary embolism likely to require thrombolytic therapy or surgery. Unstable angina and acute myocardial infarction without the presence of Q waves (Q waves appear in the presence of myocardial necrosis), often used in combination with aspirin. ST-segment elevation acute myocardial infarction: Indicated for use in combination with thrombolytics in patients with sufficient or ineligible coronary revascularization. Contraindications to use Enoxaparin:
Allergy to Enoxaparin, Heparin or derivatives of Heparin, including other low molecular weight Heparins. Coagulation dysfunction. Bleeding or the patient is at risk of uncontrolled bleeding. Have a history of severe thrombocytopenia caused by Heparin. Severe renal impairment (unless the patient is on dialysis). Brain hemorrhage. Epidural or spinal anesthesia is contraindicated. Acute endocarditis. The drug is not recommended to be used in the following cases:
Combination with aspirin (at analgesic and antipyretic doses), other NSAIDs, Dextran. In the first days after the stroke there is no bleeding. Mild to moderate renal failure.
3. Usage and dosage of Enoxaparin 60mg
3.1. How to take Enoxaparin This medication is given by injection under the skin as directed by your doctor, usually 1 or 2 times per day in the abdomen at least 5cm from the navel. Do not inject intramuscularly.
Technical instructions for subcutaneous injection:
The syringe is pre-packed by the manufacturer. Excess drug must be removed before injection, use only the prescribed dose. If there is no excess, do not push the plunger to expel air bubbles before injecting the medication. Injection site: Injected under the skin of the lateral or posterior abdominal wall, alternating between left and right. Patient lying supine: Clamp the skin between the thumb and forefinger, then use the needle to insert the needle into the selected location, must poke the needle at right angles, do not inject into the side, the entire length of the needle into the skin fold. The skin fold between the two fingers must be kept still during the injection. Note: The drug should be injected through an intravenous line. Before injection, the intravenous line must be rinsed with 0.9% sodium chloride solution or Dextrose before and after injection. This drug should not be mixed or injected simultaneously with other drugs, but can be injected with 0.9% sodium chloride solution or Dextrose. 3.2. Dosage of Enoxaparin The dose depends on each patient's case, the doctor will give appropriate indications to help the patient treat and prevent the risk of bleeding.
4. Enoxaparin side effects
Like other medicines, taking Enoxaparin can also cause the following side effects:
Very serious side effects may occur, you need to call 911 if you have any signs of an allergic reaction. the following: Rash; severe abdominal pain; shortness of breath; swelling of the face, lips, tongue, or throat.
Serious side effects that require discontinuation and medical examination:
Unusual bleeding in the nose, mouth, vagina or rectum, bleeding from a wound or needle that does not stop, bleeding that does not stop; Purple or red spots under the skin and a greater risk of bruising; pale skin, feeling light-headed or short of breath, fast heartbeat, and trouble concentrating; Black or bloody stools, coughing up blood, or vomiting something that looks like coffee grounds; Numbness, itching, or muscle weakness: Especially weakness in the legs and feet; Unable to move certain body parts; sudden weakness, severe headache, confusion, trouble speaking, seeing, or loss of balance; shortness of breath; Increased liver enzymes, hyperkalemia.... Less serious, common side effects may include: Nausea and vomiting, diarrhea; the risk of osteoporosis; fever; swelling in your hands or feet; pain, irritation, redness, or swelling at the injection site.
When taking the drug, not everyone experiences such side effects. It is possible that many people have other side effects. Therefore, if you have any problems related to taking the medicine, consult your doctor or pharmacist.
5. What should be noted when using Enoxaparin?
Before taking Enoxaparin 60mg, you should inform your doctor:
If you are allergic to drugs such as Enoxaparin, Heparin or any other drugs or allergic to pork products; Prescription and non-prescription medications you are taking, including vitamins and supplements; Tell your doctor about your medical history: Artificial heart valves; if you have or have ever had kidney disease; heart infection; stroke; bleeding disorders; ulcers or a low platelet count; uncontrolled high blood pressure; septic shock; gastrointestinal bleeding; recent surgery; risk of miscarriage; if you are pregnant or planning to become pregnant; are breastfeeding. If you become pregnant while taking Enoxaparin, contact your doctor; For women who are pregnant or breast-feeding: There are not enough studies to determine the risks of taking this medicine. Before taking medication, always consult with your doctor to weigh the benefits and risks. According to the U.S. Food and Drug Administration (FDA), Enoxaparin is in a pregnancy category B, meaning there was no risk in some studies;
Drug interactions can change the action of the drug or increase the effect of side effects. Enoxaparin may interact with certain medications used to treat or prevent blood clotting such as: Abciximab, Anagrelide, Cilostazol, Clopidogrel, Dipyridamole, Eptifibatide, Ticlopidine, Tirofiban; Urokinase; Apixaban; Rivaroxaban; Tinzaparin or Heparin.
For women weighing less than 45 kg and men less than 57 kg should be used with caution as this medicine may increase the risk of bleeding or serious bleeding.
People with kidney disease should use with caution because the drug response may be increased due to slower elimination.
Store the medicine in the refrigerator, keep the original packaging before use. Keep medicine out of reach of children.
Hopefully, through the article you have the necessary information about the drug Enoxaparin 60mg. This is a medicine prescribed by a doctor, you should not use it on your own because of the risk of serious side effects.
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