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Effemax 650 belongs to the group of pain relievers and fever reducers. The main ingredient of the drug is Paracetamol with a content of 650mg, which is prepared in the form of film-coated tablets. The following article helps you better understand the effects of Effemax.
1. What are the effects of Effemax 650?
Paracetamol (also known as Acetaminophen or N-acetyl-p-aminophenol) is an effective pain reliever and fever reducer, but has only weak anti-inflammatory properties. Its mechanism of action is inhibition of prostaglandin synthesis in the central nervous system and to a lesser extent via a peripheral action by blocking the generation of pain impulses. Peripheral activity may also result from inhibition of prostaglandin synthesis or inhibition of synthesis or action of other substances that sensitize pain receptors to chemical or mechanical stimuli.
Paracetamol can produce an antipyretic effect by acting on the thermoregulatory center of the hypothalamus to induce peripheral vasodilation leading to increased blood flow through the skin, sweating and heat loss. Central effects in the hypothalamus may be related to inhibition of prostaglandin synthesis. The drug has no effect on the cardiovascular and respiratory systems, and unlike Salicylates, Paracetamol does not cause gastric irritation or bleeding.
Effemax 650 is recommended for the treatment of most pain and fever conditions such as: migraine, toothache, neuralgia, colds and flu, sore throat, backache, rheumatic pain and dysmenorrhea.
Do not use this medicine in case the patient is allergic to Paracetamol or any of the excipients in Effemax 650. Besides, people with G6PD deficiency are also contraindicated to use.
2. Usage- Dosage Effemax 650
2.1. Effemax 650 is a film-coated tablet that should be taken orally. Using many products containing Paracetamol can harm your liver. If you regularly drink alcohol talk to your doctor before taking Effemax and never use more than 2 grams (2000mg) per day. If you are taking medication that contains Paracetamol, use the pediatric form of Paracetamol. Do not arbitrarily use Effemax 650 for children under 2 years of age without the advice of a doctor. When analgesics are used long-term (>3 months) with bi-daily dosing or more frequently, headaches may develop or worsen leading to pain-relieving headaches. In this case should not be treated by increasing the dose, Effemax 650 should be discontinued with the advice of a doctor. 2.2. Dosage Adults: Take 1 tablet / time, every 4-6 hours, do not take more than 6 tablets / 24 hours. Children from 7-12 years old: Take 1⁄2 tablets / time, at least 4 hours apart, not to take more than 3 tablets / 24 hours. Do not use more Effemax 650 than recommended. An overdose of Effemax 650 can cause serious harm. The maximum intake for adults is 1 gram (1000mg) per dose and 4 grams (4000mg) per day.
Do not arbitrarily use Effemax for pain relief in adults for more than 10 days and in children for more than 5 days or more than 3 days in case of fever of 39.5°C unless directed by a doctor.
Symptoms of an overdose of Effemax 650 in the first 24 hours are pallor, nausea, vomiting, loss of appetite and abdominal pain. Between 12 and 48 hours after an overdose, liver damage can become apparent. Abnormalities of glucose metabolism and metabolic acidosis may occur. In severe poisoning, liver failure can progress to encephalopathy, disseminated intravascular coagulation, hemorrhage, hypoglycemia, cerebral edema, gastrointestinal bleeding, and death. Acute renal failure with acute tubular necrosis, strongly suggested by loin pain, hematuria, and proteinuria may develop even in the absence of severe liver injury. Cases such as pancreatitis and cardiac arrhythmias have been reported.
In this case, the patient should be referred to an emergency hospital for immediate medical care. Symptoms may be limited to nausea or vomiting and may not reflect the severity of the overdose or the risk of organ damage. Management must follow recommended treatment guidelines.
Further measures will depend on the severity, nature and course of the clinical symptoms of Paracetamol poisoning and should follow standard intensive care procedures.
4. Possible side effects when using Effemax 650
During drug treatment, if the following allergic reactions appear, the patient should immediately go to a medical center for treatment and treatment: urticaria; shortness of breath ; swelling of the face, lips, tongue, or throat.
Some serious side effects when using Effemax 650, stop using the drug when you have the following signs: low fever accompanied by nausea, stomach pain and loss of appetite, dark urine, earth-colored stools lightning, yellow skin, yellow eyes...
5. Interaction of Effemax 650 with other drugs
Anticoagulants - the effect of Warfarin and other Coumarins may be enhanced with prolonged regular use of Paracetamol increasing the risk of bleeding. The usual recommended dose has no significant effect. Metoclopramide - in combination with Effemax 650 may increase the rate of absorption of Paracetamol. Domperidone - in combination with Effemax 650 may increase the rate of absorption of Paracetamol. Cholestyramine - in combination with Effemax 650 may reduce absorption if Paracetamol is taken within an hour. Imatinib - frequent use of Effemax 650 should be limited or avoided concomitantly with Imatinib
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