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Domenat medicine has the main ingredient DL-Alpha-Tocopherol Acetate with 400 IU content, which is commonly used in the treatment and prevention of diseases caused by vitamin E deficiency. Necessary information of Domenat drug about ingredients, Uses, dosages and side effects will help improve treatment outcomes for patients.
1. What is Domenat drug?
Domenat drug is made in the form of soft capsules, with the main ingredients including:
Active ingredients: Vitamin E (DL-Alpha-Tocopherol Acetate) content 400 IU. Excipients: Gelatin, Glycerin, Liquid Sorbitol, Sodium benzoate, Soybean Oil, Vanillin smell just enough for 1 soft capsule. Pharmacodynamics
DL-Alpha-Tocopherol or Vitamin E is a fat-soluble vitamin that protects the stability and integrity of cell membranes, and protects the functions and structures of cells through the body. inhibits oxidation of essential components in cells, preventing the formation of toxic oxidation products. Some In vitro studies show that Vitamin E also has anti-hemolytic effects, reduces platelet aggregation due to oxidants, and increases the immune response for the elderly. Vitamin E is found in foods like wheat germ oil, cottonseed oil, sunflower oil, cereals and eggs.
2. What is the effect of Domenat?
Domenat drug is indicated for the treatment of the following cases:
Prevention and treatment of symptoms related to Vitamin E deficiency. Anti-aging, preventing the appearance of wrinkles in the skin. Supports the treatment of fatty liver or hypercholesterolemia. Support the treatment of infertility in men and women, menstrual disorders, miscarriage, cardiovascular disorders...
3. Contraindications of the drug Domenat
Hypersensitivity to any of the ingredients of Domenat. History of allergy to medications containing Vitamin E (DL-Alpha-Tocopherol Acetate).
4.Domenat dosage and usage
Dosage:
Dose: Take 1 tablet (400 UI)/time x 1 time/day. Note: Take the drug with meals.
5. Notes when using Domenat
5.1 Side effects encountered when using Domenat Vitamin E active ingredient in Domenat has a high level of safety and is less likely to have unwanted side effects. However, using Domenat in high doses or for a long time can cause unwanted effects such as:
Common: Neurological symptoms such as dizziness, headache, blurred vision. Gastrointestinal disturbances such as nausea, vomiting and necrotizing enterocolitis. Uncommon: Symptoms such as breast pain, increased blood fat, decreased thyroid hormones (such as Thyroxin or Triiodothyronine in the blood), increased blood creatine kinase, increased estrogen and androgen in the urine. Rash, dermatitis and thrombophlebitis. Rare: Anaphylaxis . Stop using Domenat as soon as you notice the above side effects or other unusual symptoms, and quickly notify the treating doctor or go to the nearest medical facility for timely treatment.
5.2 Notes on the use of Domenat in subjects Avoid using Domenat in patients with Vitamin K deficiency or who are taking anticoagulants because it can cause bleeding. Administration of Domenat in preterm neonates weighing less than 1.5 kg can cause necrotizing enterocolitis. Pregnancy: Studies have shown that Vitamin E crosses the placenta in low concentrations and has virtually no harmful effects on the mother and fetus. During pregnancy, the mother can supplement the amount of Vitamin E through food, in case of poor diet, Domenat should be used for daily needs. Lactation: Vitamin E contained in Domenat can pass into breast milk. Women who are breastfeeding can supplement Vitamin E through Domenat when the menu is not enough to meet daily needs. Drivers or workers who operate machinery are almost unaffected after using Domenat.
6. Domenat drug interactions
Interactions with other drugs:
Domenat reduces the effectiveness of drugs containing Vitamin K and increases the effectiveness of anticoagulants, which may cause bleeding when used in combination. The combination of Domenat and Acetyl Salicylic Acid may increase the risk of bleeding. Domenat should be used in combination with drugs containing Vitamin A, because the active ingredient Vitamin E increases the absorption, storage and utilization of Vitamin A, and protects Vitamin A from oxidative degradation to help vitamin A concentration in cells. cells increase. In particular, Domenat also works to reduce unwanted symptoms caused by excess Vitamin A in the body. Domenat should be avoided with iron-containing medicines, as Vitamin E doses above 10 IU/kg may impair the response to iron in children with iron-induced anemia. Vitamin E supplementation at recommended doses may reduce the risk of hemolytic anemia in low birth weight infants receiving iron supplements. Domenat is reduced absorption when used with too much mineral oil. Avoid taking drugs such as Cholestyramine, Orlistat, Colestipol at least 2 hours before using Domenat because it can inhibit the absorption of active Vitamin E. Above is basic information about ingredients, uses, dosages and other benefits. Possible side effects of Domenat. In order to improve the effectiveness of treatment for themselves and their families, users should carefully read the instructions for use contained in the Domenat medicine box and follow the instructions of the treating doctor or pharmacist.
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