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Dofluzol is a group of drugs used to prevent migraine, dizziness, vestibular system dysfunction with the main ingredient Flunarizine. So what is Dofluzol?
1. What are the uses of Dofluzol?
1.1. What is Dofluzol? Dofluzol 5 mg medicine is a product of Domesco Medical Import-Export Joint Stock Company. Dofluzol 5mg with the main ingredient Flunarizine in the form of Flunarizine dihydrochloride 5mg. Dofluzol is available in the form of hard capsules. This is a drug used to prevent migraine, treat symptoms of dizziness caused by dysfunction of the vestibular system.
1.2. What does Dofluzol do? Flunarizine is an active calcium channel blocker, antihistamine, and sedative. The drug blocks calcium overload in cells, by reducing excessive calcium influx across the cell membrane. Dofluzol the main component flunarizine has no effect on myocardial contractility, it does not inhibit the sinoatrial or atrioventricular node, does not increase heart rate, has no antihypertensive effect.
Dofluzol medicine 5mg main ingredient flunarizine is used for prophylaxis in migraine, symptomatic treatment of vertigo due to vestibular or vestibular system dysfunction.
In addition, the drug also helps treat symptoms caused by cerebral circulatory insufficiency and brain cell oxygen depletion, including dizziness, headache, irritability, memory loss or poor concentration and confusion in the brain. sleep .
Some other side effects of drugs that are not listed on the approved drug label, but your doctor may prescribe you to take. Patients only use this medicine to treat certain other conditions when prescribed by a doctor.
2. Usage of Dofluzol blood pressure medicine
2.1. How to take Dofluzol You should take Dofluzol 5mg exactly as directed on the label or as directed by your doctor. Patients should not use larger, smaller or longer amounts than indicated. Patients should take this medicine in the evening after a full meal.
After 2 months of drug treatment, if symptoms do not improve, the patient is considered non-responder and treatment should be discontinued.
If the patient has any questions during the use of the drug, ask the doctor or pharmacist.
2.2. Dosage of the drug Dofluzol Usual Adult Dose for Migraine Prophylaxis
Adults under 65 years old: 10mg (2 tablets per day, respectively). Adults over 65 years old: 5mg daily. Usual Adult Dose for Dizziness:
The same dose as for migraine, however, treatment is initiated until symptom control is achieved, usually less than 2 months.
Dofluzol dosage for children: Consult your doctor before giving the medicine to your child.
Handling missed dose: If the patient forgets to take a dose of Dofluzol 5mg, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take double the prescribed dose
Treatment of overdose: Based on the pharmacological properties of the drug, drowsiness and asthenia may occur with overdose. Several cases of acute overdose (doses as high as 600 mg orally once) have been reported and symptoms such as drowsiness, tachycardia, and agitation have been observed. Currently there is no specific antidote. Within 1 hour after the overdose, the patient should be performed gastric lavage. Activated charcoal can be used if appropriate.
3. Contraindications of Dofluzole
Dofluzol 5 mg ingredient flunarizine is contraindicated for use in the following cases:
Patients with hypersensitivity to the components of the drug. Patients with porphyria. History of depression, Parkinson's or other extrapyramidal disorders.
4. Drug interactions
Dofluzol 5mg flunarizine may change the way other medicines you are taking, or increase the effect of side effects. To avoid drug interactions, it's best to write a list of all medications you're taking, including prescription drugs, over-the-counter drugs, herbs, or supplements, and give Doctors and pharmacists are known. To ensure safety when using the drug, the patient should not arbitrarily use the drug, stop or change the dose of the drug without the guidance of the doctor.
When Dofluzol 5mg is used together with sedatives, or sleeping pills, it may increase the drowsiness effect.
Dofluzol 5mg can interact with any food or drink?
Food, alcohol and tobacco can interact with certain drugs. Consult your doctor about taking your medicine with food, alcohol and tobacco. Alcohol, sedatives, and sleeping pills when used together with flunarizine increase the side effects of drowsiness. Flunarizine is not contraindicated in patients receiving beta-blockers. The pharmacokinetics of flunarizine is not affected by topiramate. The steady state pharmacokinetics of topiramate is not affected by flunarizine. Long-term use of flunarizine has no effect on concentrations of phenytoin, carbamazepine, valproate or phenobarbital. Plasma concentrations of flunarizine are generally slightly lower in epileptic patients receiving these antiepileptic agents than in healthy subjects receiving similar doses. The plasma protein binding of carbamazepine, valproate and phenytoin is not affected by the concomitant administration of flunarizine. Pregnancy: There are no studies confirming the safety of flunarizine when used in pregnant women. Therefore, this drug should not be used in pregnant women, unless the benefits outweigh the risks to the fetus.
Lactation : It is not known whether flunarizine is distributed into breast milk. Use of the drug should be considered or avoided during breast-feeding or should be taken and breast-feeding discontinued.
4. Notes when using Dofluzole
Before taking Dofluzol 5mg, the patient should tell the doctor or pharmacist if:
The patient is allergic to any of the ingredients. Are taking other medications (including prescription and nonprescription drugs, herbs, and supplements). Patients who are or have ever had medical conditions such as depression, Parkinson's symptoms. Are planning to give the drug to children or the elderly. Dofluzol may make you drowsy. You should not drive, use machines, or do anything that requires alertness until you can do it safely. Treatment with Dofluzol may increase extrapyramidal symptoms, depression and the onset of Parkinson's syndrome, especially in at-risk patients such as the elderly. Fatigue may increase during treatment with Dofluzol, in which case you should discontinue treatment. Treatment with flunarizine may increase depressive symptoms, extrapyramidal symptoms, and exacerbation of Parkinson's syndrome, particularly in at-risk patients such as the elderly. Therefore, it should be used with caution in these patients. Patients with galactose intolerance, patients with Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
5. Side effects of the drug Dofluzol 5mg
Side effects patients may experience when taking Dofluzol drugs such as: drowsiness, fatigue, anxiety, weight gain, increased appetite, depression, extrapyramidal symptoms (such as slow movement, stiffness, lying down). restlessness, dyskinesia, tremor).
Besides, the patient may also experience burning in the sternum, nausea, stomach pain, increased lactation, dry mouth, muscle pain, rash.
This is not a complete list of side effects and others may occur. If you have any questions about side effects, consult your doctor or pharmacist.
Store Dofluzol 5mg in a dry place, away from light, at a temperature below 30°C. It should be stored in the original packaging of the medicine.
Dofluzol is a group of drugs used to prevent migraine, dizziness, vestibular system dysfunction with the main ingredient Flunarizine.
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