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Dianfagic drugs with Paracetamol and Tramadol ingredients are made in capsule form. It is indicated in the treatment of moderate to severe pain. However, when using the drug can experience some unwanted side effects, so the patient needs to learn and consult with the treating doctor.
1. What is Dianfagic?
Dianfagic drug includes 2 compounds Paracetamol and Tramadol, both of which are effective in reducing pain. When Dianfagic is taken orally, Tramadol is absorbed more slowly but has a longer half-life than Paracetamol. Complete bioavailability of Tramadol averages about 75% following oral dosing and peak plasma concentrations are reached in 2 to 3 hours in healthy adults receiving a 2-tablet dose. Paracetamol absorption after oral administration is also completely accomplished in the small intestine and peak plasma concentrations are possible within 1 hour with no effect if co-administered with Tramadol.Dianfagic taken with food did not affect or change the peak plasma concentration or absorption of the 2 compounds contained in the drug. Therefore, the use of the drug does not depend on the meal.
2. What disease does Dianfagic drug treat?
Dianfagic is used in the treatment of moderate to severe pain. Especially for cases of pain relief with Aspirin or Paracetamol alone but not effective.However, Dianfagic is also contraindicated in some cases such as:
Pregnant women and lactating women. These subjects should not use the drug because currently the safety level for these subjects has not been thoroughly studied. Dianfagic should not be used in infants and children under 12 years of age.
3. Dosage and usage of the drug Dianfagic
Dianfagic is used for both adults and children.
For adults and children over 12 years old when using Dianfagic drugs can apply with a maximum dose of 1 to 2 tablets between 4 and 6 hours each time. Do not use more than 8 tablets in a day. For children under the age of 12, the benefits and risks of using the drug should be carefully researched and should be followed by the treatment prescribed by the doctor. For older adults who may be over 65 years of age, no studies have found a difference in safety or pharmacokinetics in this subject's use of the drug compared with younger people. . Note: The above recommended therapeutic doses are for reference only. Therefore, before using Dianfagic, patients should be prescribed by a doctor.
If a patient using Dianfagic forgets a dose, the missed dose can be used as soon as he remembers. However, if the interval between the missed dose of Dianfagic and the next dose is close, the patient can skip the missed dose and take the next dose. Patients should also note that it is not recommended to double the dose of Dianfagic, because it can cause drug overdose and unwanted side effects affecting current health.
In case the patient accidentally takes Dianfagic drug in excess of the prescribed dose and has some signs of unwanted side effects, it is necessary to take the patient to the nearest emergency medical facility for assistance. timely medical assistance, helping patients overcome dangerous conditions.
In case of overdose of Dianfagic drug, clinical manifestations may appear with signs or symptoms related to Tramadol or Paracetamol poisoning or both:
In case of Tramadol poisoning, it is possible Severe consequences when overdose occurs symptoms of respiratory failure, coma, convulsions, cardiac arrest and even death. With the case of Paracetamol poisoning due to using high doses can cause liver toxicity with early symptoms that may occur after liver damage such as gastrointestinal irritation, the patient has a feeling of loss of appetite, nausea and vomiting. vomiting, irritability, paleness, or sweating. Symptoms of hepatotoxicity may appear 48 to 72 hours after taking the drug.
4. Side effects and some notes when using Dianfagic drugs
When using Dianfagic drugs may occur side effects on the central nervous system and digestive system. The most common symptoms are nausea, dizziness, drowsiness, and dizziness. However, some less frequent side effects may still occur such as:
Whole body weakness , aches and possibly palpitations. Central nervous system and peripheral nervous system with symptoms of headache or tremor. The digestive system includes signs of abdominal pain, constipation, diarrhea, dyspepsia, flatulence, dry mouth. Nervous system disorders with loss of appetite, anxiety, confusion, insomnia, restlessness. In rare cases, side effects may occur, causing patients to feel chest pain, chills, fainting, high blood pressure or severe hypotension, arrhythmias, rapid pulse ..
When using Dianfagic, patients should be cautious because the drug can cause a risk of convulsions when used concurrently with drugs capable of inhibiting serotonin reuptake or tricyclic compounds or sedative drugs. or, for patients with epilepsy, a history of seizures.
Besides, using Dianfagic drug should also be cautious in the following cases:
The drug has the effect of increasing the risk of respiratory failure in patients with respiratory failure. The case of concomitant use of drugs with central nervous system depressants such as alcohol, anesthetics, sedatives should be cautious and considered before use. Patients who are addicted to opiates should avoid using the drug because it can increase the likelihood of relapse. Patients with alcohol dependence should be cautious in using Dianfagic because of possible effects and increased risk of hepatotoxicity. Patients with creatinine clearance less than 30ml/min should use the drug at a dose of not more than 2 tablets and about 12 hours apart. Some Dianfagic Drug Interactions: Dianfagic used with MAO inhibitors or serotonin reuptake inhibitors may increase the risk of side effects with symptoms of seizures and Serotonin syndrome. Dianfagic used with carbamazepine significantly increases the metabolism of tramadol. The analgesic effect of this compound may be reduced. The use of Dianfagic with Quinidine may increase the concentration of Tramadol, however, the clinical outcome of this interaction is unknown. The article has provided information about what drug Dianfagic is, its uses, dosage and usage. To ensure the safety and effectiveness of treatment, patients should carefully read the instructions for use, consult a doctor / pharmacist before use.
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