This is an automatically translated article.
Dexibuprofen belongs to the group of non-steroidal anti-inflammatory drugs. Dexibuprofen is also the main ingredient of the drug. Dexibuprofen is available in both capsules and film-coated tablets, with different strengths such as Dexibuprofen 200mg, Dexibuprofen 300mg, Dexibuprofen 400mg.
1. Uses of Dexibuprofen
Dexibuprofen belongs to the group of non-steroidal anti-inflammatory drugs, with the main active ingredient being Dexibuprofen. This active ingredient has anti-inflammatory, analgesic and antipyretic effects similar to other non-steroidal anti-inflammatory drugs. Especially, it has good anti-inflammatory and pain-relieving effects in the treatment of degenerative joint diseases.
Dexibuprofen is prepared in 2 forms of film-coated tablets and capsules, each with the following content:
Dexibuprofen 200mg; Dexibuprofen 300mg ; Dexibuprofen 400mg. Dexibuprofen is indicated for use in the following cases:
Pain relief and anti-inflammatory: Toothache, mild rheumatism, headache, menstrual pain, after surgery; Pain relief, antipyretic, anti-inflammatory: Rheumatoid arthritis, osteoarthritis, spondyloarthritis, back pain, dry arthritis, tendinitis, tendonitis, sprains, synovitis.
2. Dosage and how to take Dexibuprofen
The way to take Dexibuprofen is to take the tablet whole with water. Dosage of Dexibuprofen in adults is as follows:
Osteoarthritis, dysmenorrhea: 600-900mg/day, divided into 2-3 times/day, equivalent to 200-300m/time, the maximum dose is 1200mg/day for acute pain. Mild to moderate pain: 600mg/day, divided into 3 times, equivalent to 200mg/time, the maximum dose is 1200mg/day for acute pain. Note, for patients with mild and moderate hepatic and renal dysfunction, the initial dose of Dexibuprofen should be reduced and the patient should be closely monitored during drug administration.
Dexibuprofen overdose can cause common but mild symptoms such as nausea, vomiting, abdominal pain, headache, drowsiness, tinnitus, nystagmus, ataxia, coma.
In addition, overdose of Dexibuprofen has rarely caused moderate or severe symptoms such as hypotension, hypothermia, gastrointestinal bleeding, metabolic acidosis, impaired renal function, and respiratory failure in humans. growth, transient apnea, convulsions, coma.
When using Dexibuprofen overdose, the patient should be treated symptomatically and note that there is no specific antidote. To reduce digestive disorders caused by drugs, water can be used to dilute the concentration of the drug. Activated charcoal is used in cases where the patient has taken a significant amount of medication. Emesis or gastric lavage should be considered depending on the duration of dosing.
3. Dexibuprofen side effects
Dexibuprofen can cause some unwanted side effects with the following frequency:
Common: Fatigue, fever, dizziness, dizziness, restlessness, headache, nausea, vomiting, abdominal bloating, floating rash, rash. Uncommon: Allergic reactions (appears only in asthmatics), urticaria, rhinitis, abdominal pain, gastrointestinal bleeding, progressive peptic ulcer, insomnia, tinnitus, lethargy, hearing loss reduced force, visual disturbances, prolonged bleeding time. Rare: Dexibuprofen rarely causes rash, Stevens-Johnson syndrome, edema, hyponatremia, leukopenia, thrombocytopenia, neutrophils, granulocytopenia, eosinophilia, anemia, alopecia, decreased visual acuity, color vision disorder, blurred vision, photosensitivity, Crohn's syndrome, necrotizing enterocolitis, pancreatitis, gallbladder contractile disorder, hepatotoxicity, abnormal liver function, interstitial nephritis , cystitis, nephrotic syndrome, acute renal failure, hematuria, depression, aseptic meningitis, coma. When seeing any strange symptoms after taking Dexibuprofen, the patient should contact a doctor or visit a medical facility for advice on how to handle it.
4. Some notes when taking Dexibuprofen Do not use Dexibuprofen in people with hypersensitivity to the ingredients of the drug as well as other non-steroidal anti-inflammatory drugs, especially substances that may have caused asthma, spasms. bronchi, acute rhinitis, nasal polyps, urticaria or angioedema. Dexibuprofen should not be used in patients with a history of gastrointestinal bleeding, gastrointestinal perforation (associated with nonsteroidal anti-inflammatory drugs), history of active or recurrent peptic ulcer, Crohn's disease, ulcerative colitis active, cerebrovascular or other active bleeding, severe heart failure, severe renal dysfunction, severe liver failure, women who are 6 months pregnant. People with a history of bronchial asthma due to antibiotics Non-steroidal inflammation, bronchospasm should be cautious when using Dexibuprofen. People with a history of hypertension, mild and moderate congestive heart failure should be counseled and monitored during the use of Dexibuprofen. People with kidney disease, liver disease, at risk of edema, fluid retention, kidney failure should be cautious when using Dexibuprofen. For women in the last 3 months of pregnancy, it is necessary to limit the use of Dexibuprofen or other non-steroidal anti-inflammatory drugs because the drug can inhibit uterine contractions, delay the delivery process. In addition, the drug also causes the newborn to have severe respiratory failure, severe pulmonary hypertension because it causes premature closure of the ductus arteriosus in the uterus. Dexibuprofen also increases the risk of bleeding and inhibits platelet function. Therefore, the drug should not be used in pregnant women a few days before giving birth. Dexibuprofen should not be used in lactating women, although the drug is rarely excreted in breast milk. Limit driving or operating machinery because Dexibuprofen can cause drowsiness, fatigue, dizziness, visual disturbances. However, if a single dose or short-term use is used, no precaution is necessary. Dexibuprofen interacts with drugs: Causing stomach bleeding, reducing cardiovascular effects, increasing the risk for cardiovascular when used with Aspirin, Warfarin; increased plasma lithium concentration and decreased renal elimination; Patients taking Dexibuprofen together with ACE inhibitors or angiotensin II receptor blockers should have their blood pressure monitored closely; increased risk of gastric ulcer when used concomitantly with corticosteroids; increase the side effect of quinolone antibiotics on the central nervous system and lead to convulsions; increased risk of bleeding and ulceration when Dexibuprofen is taken with other non-steroidal anti-inflammatory drugs; reduce the diuretic effect of furosemide and diuretics; increased plasma digoxin concentrations. In summary, the use of Dexibuprofen is pain relief, anti-inflammatory and antipyretic for bone and joint diseases such as rheumatoid arthritis, osteoarthritis... and some mild pain conditions such as headache, toothache, dysmenorrhea...
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