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Ceteco Viba 4 is a drug with strong anti-inflammatory effects, used in cases of pain caused by inflammation or autoimmune diseases that cause an inflammatory response. Medicines bring high treatment efficiency and reduce side effects if you take it correctly.
1. What is Ceteco viba 4?
Ceteco viba 4 contains the main active ingredient, Methylprednisolone 4mg, in the form of film-coated tablets.
Methylprednisolone is a synthetic glucocorticoid with strong anti-inflammatory, immunosuppressive and anti-proliferative effects.
Methylprednisolone has the effect of reducing inflammation by reducing the synthesis of inflammatory chemical mediators such as Progastadine, Thromboxane,... At the same time, inhibiting and making white blood cells to the damaged area less. Thereby reducing symptoms caused by inflammation such as swelling, heat, redness, pain. Like other glucocorticoids, it also has immunosuppressive effects when used in high doses and reduces cell proliferation due to decreased cell protein synthesis or gene transcription. This drug also increases the production of glucose from glycogen in the liver causing hyperglycemia, affecting the ability to control blood sugar.
2. What are the uses of Ceteco viba 4?
Ceteco viba 4 is indicated for use in the following cases:
Rheumatoid arthritis, systemic lupus erythematosus, some forms of vasculitis, peritemporal artery inflammation, nodular periarteritis; Sarcoid disease, bronchial asthma ; Chronic ulcerative colitis, hemolytic anemia, granulocytopenia; Severe allergic conditions, including anaphylaxis; Used in the treatment of cancer, such as acute leukemia, lymphoma, breast cancer and prostate cancer. Methylprednisolone is also indicated in the treatment of primary nephrotic syndrome. Adrenal insufficiency: Used as hormone replacement, but needs to be combined with other drugs. Do not use Ceteco viba 4 in the following cases:
There is a history of hypersensitivity to any component of the drug. Systemic fungal infections: Because Ceteco viba 4 reduces immunity, it can make this condition worse. Do not use for people who are suffering from peptic ulcer, high risk of gastrointestinal bleeding. Long-term treatment with this drug is contraindicated in patients with a history of peptic ulcers, severe osteoporosis, patients with a history of psychosis, herpes. Severe infections except bacteremia, viral infections, tuberculosis (except tuberculous meningitis).
3. Dosage and how to use Ceteco Viba 4
How to take the drug:
The drug is in the form of film-coated tablets that should be taken orally. The drug needs to be taken with a full glass of water and the best time to take the drug is from 8 to 9 am, after eating. When taking the drug, it is not necessary to stop suddenly, but it is necessary to comply with the measure of dose reduction, then stop taking it. Dosage instructions vary from case to case. Initial dose is 4 - 48mg/day, use as a single dose or in divided doses depending on the disease.
Multiple sclerosis: Oral at a dose of 160mg/day x 1 week, followed by 64mg, once every 2 days for a month. Rheumatoid arthritis: The starting dose is usually low 4-6mg/day. Acute episodes take 16-32mg/day, then rapidly decrease. Severe rheumatoid arthritis: Use at a dose of 0.8mg/kg/day divided into small doses, then take a single daily dose. Acute asthma attack: Use at a dose of 32-48mg/day x 5 days, then may add additional treatment with a lower dose for one week, when the acute attack is over, Methylprednisolone is tapered rapidly. Chronic arthritis in children with serious life-threatening complications: Used in the initial therapy from 10-30mg/kg/time, usually 3 times. Chronic ulcerative colitis: Use at a dose of 8-24mg/day. Primary nephrotic syndrome: Start oral at 0.8-1.6 mg/kg for 6 weeks, then gradually reduce dose over 6-8 weeks. Immune hemolytic anemia: Oral 64mg/day for at least 6-8 weeks, then gradually reduce the dose. Sarcoid disease: Oral at a dose of 0.8mg/kg/day. Then use a maintenance dose of 8mg/day. Missed dose and overdose:
Missed dose: Take the missed dose as soon as you remember it. Do not take a double dose next time. Overdose: Symptoms of overdose, including Cushing's syndrome, muscle weakness and severe osteoporosis, occur only with long-term, high-dose glucocorticoids. In these cases, a decision should be made to suspend or completely stop taking glucocorticoids and treat supportive symptoms.
4. Undesirable effects of the drug Ceteco viba 4
Some side effects of the drug include:
Common:
Central nervous system: Insomnia, nervous excitability. Digestion: Increased appetite, slow digestion. Hirsutism, diabetes, joint pain, cataracts, glaucoma, nosebleeds. Uncommon:
Central nervous system: Dizziness, convulsions, psychosis, pseudotumor cerebri, headache, mood swings, delirium, hallucinations, euphoria. Edema, hypertension, acne, skin atrophy, bruising, hyperpigmentation. Endocrine and metabolic: Cushing's syndrome, suppression of the pituitary-adrenal axis, growth retardation, glucose intolerance, hypokalemia, alkalosis, amenorrhea, sodium and water retention, increased blood glucose. Gastrointestinal: Gastric ulcer, duodenal ulcer, esophagitis, nausea, vomiting, abdominal distension, pancreatitis. Muscle weakness, osteoporosis, risk of pathological fractures. Hypersensitivity reactions can also occur but are rare. When taking the drug, if you experience any side effects, you need to inform your doctor for advice and appropriate treatment.
5. Notes when using Ceteco Viba 4
Use the drug exactly as prescribed, do not change the dose or stop it without being prescribed by the doctor. Use the drug with caution in patients with osteoporosis, people with vascular connections, mental disorders, peptic ulcers, patients with diabetes, hypertension, heart failure, growing children. . Due to the increased risk of adverse reactions in children and the elderly, systemic corticosteroids must be used with caution, at the lowest possible dose and for the shortest possible duration. Acute adrenal insufficiency can occur when you stop taking the drug suddenly after long treatment, taking high doses, or under stress. There is a risk of infection when you take the drug due to a weakened immune system. Protect the body from pathogens, avoid contact with people with infectious diseases. Long-term or high-dose use may affect the effectiveness of the vaccine. Do not receive vaccinations while taking the medicine. Pregnancy: Long-term administration of systemic corticosteroids to a pregnant mother may lead to weight loss in the neonate. Therefore, when using corticosteroids for pregnant women, it is necessary to weigh the potential benefits against the risks to both mother and baby. Lactation: There are no contraindications to corticosteroids in breast-feeding. But be very careful when taking the drug. Interactions with other drugs:
Methylprednisolone is an inducer of cytochrome P450 enzyme, a substrate of P450 3A enzyme, so this drug affects the metabolism of drugs such as Cyclosporin, Erythromycin, Phenobarbital, Phenytoin, Carbamazepine, Ketoconazole. , Rifampicin. Co-administration of Phenytoin, Phenobarbital, Rifampicin and hypokalemic diuretics may reduce the effectiveness of Methylprednisolone. Methylprednisolone may cause hyperglycemia, so higher doses of insulin or antidiabetic agents may be required. Storage: Temperature not exceeding 30 degrees Celsius, cool dry place, avoid direct light. Keep out of reach of children
Ceteco viba 4 has a wide range of indications for use in many different diseases. To use the drug effectively and safely, you need to do exactly as prescribed by your doctor. Do not arbitrarily use drugs because there is a risk of harm to the body.
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