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Cephalova belongs to the group of drugs that treat parasites, infections, viruses and fungi. The drug is prepared in the form of a powder for injection, containing the main active ingredient is Cephalothin, a first-generation Cephalosporin antibiotic. Here are detailed information about what Cephalova has and what to expect when used.
1. What effect does Cephalova have?
The active ingredient Cephalothin in Cephalova is often the second choice for the treatment of infections that are complicated or caused by Gram-positive cocci and susceptible Gram-positive bacilli. The drug is also used as an alternative in people who are allergic to penicillin.With the above mechanism, Cephalova is indicated in the treatment of the following diseases:
Sepsis; Inflammation of the endocardium; Osteomyelitis ; Complicated urinary tract infections; Respiratory tract infections such as bacterial pneumonia, lung abscess...; Abdominal and intestinal infections; Postoperative infection. Note: Before and during treatment with Cephalova, it is necessary to carry out culture, susceptibility testing of bacteria, and test of kidney function when indicated.
2. Dosage of Cephalova
Cephalova dosage reference as follows:
Cephalova 0.5 - 1g dose every 4-6 hours by slow intravenous injection for 3-5 minutes or continuous or intermittent injection. For severe infections, doses of Cephalova can be taken up to 12g per day. Dosage of Cephalova above is for reference only. The specific dose of Cephalova will depend on the condition and the progression of the disease. To get the right dose of Cephalova, patients need to consult their doctor/pharmacist.
3. Contraindications to the use of Cephalova
Cephalova is contraindicated in people with a history of allergy to any of the ingredients in the drug and the Cephalosporin group of antibiotics.
4. Interactions with other drugs
Possible interactions if Cephalova is used concurrently with the following drugs:
Cephalova use with nephrotoxic drugs such as Aminoglycoside antibiotics (Gentamicin) may increase the risk of kidney damage; Some cases of increased toxicity when taking Cephalova with loop diuretics such as furosemide; Probenecid inhibits renal excretion of Cefalotin, so avoid concomitant use of these two drugs; Cephalova may interfere with the measurement of creatinine by the Jaffé method because of its high value; Cephalova also gives false-positive Coombs test results and interferes with blood cross-reactivity. The urine of patients treated with Cephalova may give a false-positive glucose reaction with a copper reduction reaction. To avoid unwanted interactions when using Cephalova, patients should inform their doctor/pharmacist of all medications and dietary supplements they are using.
5. Side effects of the drug Cephalova
Cephalova can cause some side effects as follows:
Pain at the injection site; Diarrhea; Eosinophilia; Bleeding easily under very slight impact; A papule skin rash; Fever; Urticaria; Have a serum sickness-like reaction; Anaphylaxis ; Decrease in neutrophils/platelets; Hemolytic anemia; The Coombs test was positive. Pseudomembranous colitis, nausea/vomiting. Nephrotoxicity with increased blood urea/creatinine; Interstitial nephritis; Cholestatic jaundice, increased AST and ALT levels; Athritis; Candida infection ; Thrombophlebitis after infusion; High doses can cause convulsions and signs of CNS toxicity, especially in patients with renal failure. During the course of treatment, if you have any unusual symptoms suspected of using Cephalova, you need to notify your treating doctor for timely treatment.
In summary, Cephalova is a drug that is used in the treatment of bacteremia, urinary tract, respiratory, abdominal, intestinal or postoperative infections. To ensure safety for health and maximize the effectiveness of treatment, patients need to take Cephalova exactly as directed by their doctor.
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