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Cefurimaxx belongs to the group of drugs that treat parasites, anti-infectives, antivirals and antifungals. So what are the effects of Cefurimaxx and what precautions should be taken when using it? Let's find out information about Cefurimax drug through the following article.
1. What is Cefurimaxx?
Cefurimaxx belongs to the group of anti-parasitic, anti-infective, anti-viral drugs. Indicated in the treatment of otitis media, tonsillitis, sinusitis, pneumonia, pyelonephritis, cervicitis...
Cefurimaxx medicine has the main active ingredient Cefuroxim (in the form of Cefuroxim axetil) 250mg amount. Excipients in sufficient quantity.
Cefurimaxx is made in the form of film-coated tablets, packaged in boxes of 2 blisters x 10 tablets.
2. What are the effects of Cefurimax?
Cefurimaxx drug is composed by the main ingredient is Cefuroxime, has the following specific characteristics:
2.1. Pharmacodynamics: Active ingredient Cefuroxime is a Cephalosporin antibiotic, a broad-spectrum semi-synthetic antibiotic. Cefuroxime axetil is a precursor of Cefuroxime, which has very little antibacterial activity when it has not been hydrolyzed to Cefuroxime in the body after absorption. Cefuroxime is antibacterial by inhibiting bacterial cell wall synthesis by binding to essential target proteins (penicillin-binding proteins). This active ingredient has an effective and very specific antibacterial effect against many common pathogens, including beta-lactamase/cephalosporinase strains of Gram-negative (-) and Gram-positive (+) bacteria. In particular, the active ingredient Cefuroxime is very stable to many beta-lactamase enzymes of Gram-negative (-) bacteria. 2.2. Pharmacokinetics: Following oral administration, Cefuroxime axetil is absorbed from the gastrointestinal tract and rapidly hydrolyzed in the intestinal mucosa in the blood to release Cefuroxime into the systemic circulation. Taking the medicine with a meal can best absorb the drug. Peak serum concentrations are reached approximately 2 to 3 hours after oral dosing with meals. The serum half-life is 1 to 1.5 hours. The degree of protein binding is from 33 to 50% depending on the method and dose used. Cefuroxime is eliminated by glomerular filtration and tubular secretion. Cefurimaxx is indicated for use in the following cases:
Treatment of lower respiratory tract infections: Pneumonia, acute and chronic bronchitis. Treatment of upper respiratory tract infections: otitis media, sinusitis, tonsillitis, laryngitis, pharyngitis. Treatment of urinary-genital infections: cystitis, pyelonephritis, urethritis. Treatment of skin and soft tissue infections: boils, impetigo, pyoderma. Treatment of typhoid fever. Treatment of gonorrhea, cervicitis, uncomplicated acute urethritis caused by gonorrhea.
3. How to use Cefurimaxx
3.1. How to use Cefurimaxx: For the drug Cefurimaxx, patients use it orally. Take medicine after eating.
3.2. Dosage of Cefurimaxx: The recommended dose of Cefurimaxx for each subject is as follows:
Adults:
Most Infections: Dosage 250mg x 2 times/day. Typhoid fever: Dosage 500mg x 2 times/day. Urinary-genital infections: Dosage 125mg x 2 times/day. Mild to moderate lower respiratory tract infections: 250mg twice daily. Severe lower respiratory tract infections, suspected pneumonia: Dosage 500mg x 2 times/day. Pyelonephritis: Dosage 250mg x 2 times/day. Uncomplicated gonorrhea: Use a single dose of 1g. Early stage Lyme disease: Dosage 500mg x 2 times/day, treatment for 20 days. Children:
Most infections: Dosage 125mg x 2 times/day, maximum dose 250mg/time. Typhoid fever: Dosage 250mg x 2 times/day. Children 2 years of age and older with otitis media or serious infections: Dosage: 250mg x 2 times / day. 3.3. How to deal with forgetting, overdosing Missed dose:
There are no documents showing adverse effects when forgetting a dose of Cefurimaxx. In case of missed dose, take the extra dose as soon as you remember. Never use a double dose at the same time. Patients need to take the full dose prescribed to achieve the most accurate effect.
Overdose:
Most of the time Cefurimax overdose causes only nausea, vomiting and diarrhea. Less common symptoms include neuromuscular hyperexcitability and convulsions, especially in patients with renal failure.
How to deal with an overdose of Cefurimaxx:
If you experience any adverse effects when taking an overdose of Cefurimaxx, the patient should stop taking the drug and immediately notify the treating doctor. Administer anticonvulsant therapy if clinically indicated. Protect the respiratory tract and support ventilation for the patient. Cefuroxime serum concentrations can be reduced by dialysis.
3.4. Contraindications Cefurimax Drug Cefurimax is contraindicated in the following cases:
Cases where the patient is allergic, sensitive to Cefuroxim or any of its ingredients. The patient has a history of allergy, hypersensitivity to Cephalosporin antibiotics.
4. Notes when using Cefurimaxx
Notes and cautions when using Cefurimaxx:
Allergy to penicillin. Note that pseudomembranous enteritis should be diagnosed when severe diarrhea occurs after antibiotics. Be careful when using the drug in the elderly, children under 15 years old, patients with liver failure, kidney failure, subjects with myasthenia gravis, stomach ulcers, hepatic coma. For pregnant women: It is necessary to consider and consult with the treating doctor before deciding to use the drug. For lactating women: The benefits/risks to mother and baby should be carefully weighed. Consult your doctor before deciding to use Cefurimaxx. Drivers and machine operators: There have been no reports of the effects of this drug on this subject. However, caution should be exercised against some of the side effects of the drug that may be detrimental to your ability to perform these activities. Side effects when using Cefurimaxx:
When using Cefurimaxx, the following undesirable effects may be encountered:
Common:
Rash, erythema multiforme, toxic skin necrosis, rash medal . pruritus, fever, serum sickness. Uncommon:
Diarrhea, nausea, vomiting, eosinophilia, elevated liver enzymes. Rare:
Pseudomembranous enterocolitis, leukopenia, thrombocytopenia. If there is any abnormality when using Cefurimaxx, the patient should immediately notify the treating doctor.
Interactions, incompatibilities with Cefurimaxx drugs:
Consider when using Cefurimax together with tobacco, beverages or foods with alcohol or yeast. Studies or recommendations usually only state common drug interactions. Therefore, users should not arbitrarily apply information about Cefurimaxx drug interactions without being a doctor, researcher, or medical person in charge. Storage of Cefurimaxx: Store the drug at the specified temperature according to the instructions for use stated on the package. Keep the medicine in a cool, dry place away from moisture and avoid direct sunlight.
Above is all necessary information when using Cefurimaxx. Cefuroxime is a drug belonging to the group of antiparasitic, anti-infective and anti-viral drugs. Hopefully the article has provided all the necessary notes for readers when using Cefurimaxx.
