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Cefoxitin 2g is an antibiotic of the Cephalosporin group of powder for injection used in the treatment or prevention of certain bacterial infections. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to take drugs according to prescription or consult a doctor, professional pharmacist.
1. What is the use of Cefoxitin 2g?
Cefoxitin 2g is an antibiotic of the 2nd generation Cephalosporin group, prepared in powder form for injection and packaged in vials. Each vial contains 2000mg of Cefoxitin and a number of other excipients sufficient.
Cefoxitin 2g is used in the treatment of infectious diseases or prevention of infection in patients requiring surgery. The bactericidal effect of Cefoxitin is due to its ability to inhibit the synthesis of the bacterial cell wall, thereby preventing the growth of bacteria.
Thanks to that, Cefoxitin 2g is indicated for the treatment of the following diseases:
Lower respiratory tract infections (such as lung abscesses, pneumonia, ...) Urinary tract infections. Intra-abdominal infections such as: abdominal abscess, peritonitis Gynecological infections:, Pelvic cellulitis, endometritis, pelvic inflammatory disease,... Blood infections Bone and joint infections Skin infections and skin structures. Prophylaxis of infection in patients with cesarean section, vaginal hysterectomy, abdominal hysterectomy, gastrointestinal surgery.
2. How to use Cefoxitin 2g?
Cefoxitin 2g is a drug that is prepared in the form of a powder for injection, so the drug needs to be mixed with a solution for injection and put into the body by injecting the drug deep into the muscle layer, or injecting or infusing the drug into a vein.
2.1 Some notes when using Cefoxitin 2g Before using the drug, you should inform your doctor if in the following cases:
Allergic to Cefoxitin, to the remaining ingredients of the drug or other drugs. other antibiotics of the beta-lactam group. History of penicillin allergy, kidney disease, liver disease, gastrointestinal disorders, diabetes, congestive heart failure, cancer, recent surgery or emergency, malnutrition. Are pregnant or breastfeeding. In the process of using Cefoxitin 2g, it should be noted:
Ensure that the drug preparation process is carried out under aseptic conditions to avoid contamination of the injection and the injection tip. Observe the injection solution for residue, foreign particles, or discoloration, if so, discard the vial and dispose of it properly. The drug is for single use only, and the excess after use must be discarded. Administer the drug at equal intervals to ensure that the antibiotic concentration is always maintained. Use Cefoxitin for as long as indicated, even if symptoms improve rapidly. Skipping doses can lead to resistant bacteria and an increased risk of infection. Tell your doctor if symptoms persist or get worse. The reconstituted solution must be used within 6 hours at room temperature or 7 days in the refrigerator at a temperature lower than 5 degrees Celsius. Carefully follow all preparation and storage instructions for Cefoxitin 2g. Store unmixed medication at cool room temperature, away from direct light. 2.2 How to prepare Cefoxitin 2g For deep intramuscular injection, each bottle of Cefoxitin 2g will be mixed with 4ml of distilled water for injection, shaken to dissolve the powder. Then, the drug is withdrawn into the pump and injected into places with large muscle mass such as buttocks, thighs, avoiding injection into blood vessels.
Slow intravenous injection: Each vial of Cefoxitin 2g is dissolved in 10 or 20ml of distilled water for injection. Then also shake well to dissolve the powder and withdraw the drug into the pump, the injector selects the large peripheral veins and delivers the drug intravenously for 3 to 5 minutes. Intravenous infusion: first inject 10ml of distilled water for injection into the 2g Cefoxitin vial, then shake well to dissolve the powder. Continue to dilute this solution in 50ml to 1000ml of solvents such as: 0.9% sodium chloride solution, 5% or 10% dextrose solution, 5% dextrose and 0.9% sodium chloride solution, Ringer Lactate solution. . For intermittent infusion methods, care should be taken to temporarily discontinue the infusion of other solutions during the infusion of cefoxitin solutions.
2.3 Dosage of Cefoxitin 2g Cefoxitin 2g is a prescription drug, used only when prescribed by a doctor, so the specific dose for your condition will be specifically guided by your doctor. Cefoxitin dosage below is for reference only.
For adults:
Uncomplicated infections: 1g every 6-8 hours by injection or intravenous infusion. Uncomplicated urinary tract infections: 1g intravenous injection or infusion every 6-8 hours or 1g intramuscular injection, twice a day. Moderate to severe infections: 1g every 4 hours by injection or intravenous infusion; or injection, intravenous infusion 2 g drug every 6-8 hours. Uncomplicated gonorrhea IM 2 g/day as a single dose in combination with oral probenecid 1 g at the same time or 1 hour before. When high doses are needed to treat infections, 2 grams of injection or intravenous infusion every 4 hours can be used; or 3 grams injection, intravenous infusion, every 6 hours, 12 grams per day. For children 3 months of age and older, the recommended dose is 20 to 40 mg of the drug per kg of body weight, spaced 6-8 hours apart. In severe cases, the dose of Cefoxitin can be up to 200 mg/kg/day. However, the total dose should not exceed 12g/day.
Prophylaxis in adults: 2 g dose 30 minutes to 1 hour before surgery, then every 6 hours every 6 hours from the first dose not more than 24 hours.
Prophylaxis of infection in children 3 months of age and older: 30-40 mg/kg intravenously before surgery, then 30-40 mg/kg every 6 hours from the first dose not more than 24 hours.
People who have cesarean section: give a single intravenous dose of 2 g Cefoxitin immediately after clamping the umbilical cord.
3. Side effects of Cefoxitin 2g
During the use of the drug, you may experience some side effects. Therefore, get medical help right away if you have any of the following symptoms:
Allergic reaction: swelling of the face, throat, difficulty breathing, rash Serious skin reaction: fever, sore throat, burning in the inside eyes, red or purple skin rash, which may be accompanied by blistering and peeling. Call your doctor right away if you have any of the following signs:
Severe stomach pain, bloody diarrhea; Urinary incontinence or urinary retention Jaundice or yellow eyes Seizures Fever, chills, fatigue Pale skin, easy bruising, unusual bleeding, cold limbs. Common side effects of using Cefoxitin 2g may include:
Pain, swelling, bruising or other irritation at the injection site; Diarrhea; Fever; Itching, rash. Cefoxitin 2g is an antibiotic of the Cephalosporin group of powder for injection used in the treatment or prevention of certain bacterial infections. To ensure the effectiveness of treatment and avoid unwanted side effects, patients need to take drugs according to prescription or consult a doctor, professional pharmacist.
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