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Cefoperazone ABR 2g belongs to the group of drugs that treat parasites, antivirals, antifungals and anti-infectives. The drug is used in the treatment of many different diseases, however, the use of Cefoperazone ABR should be followed by a doctor's prescription.
1. What is Cefoperazone ABR 2g?
Cefoperazone ABR is a product manufactured by Balkanpharma-Razgrad AD Company from Bulgaria. The main ingredient of the product is Cefoperazon with a content of 2g.
This is one of the semi-synthetic antibiotics of the 3rd generation Cephalosporin group. This active ingredient is capable of inhibiting the synthesis of the growing and dividing bacterial cell wall to kill bacteria effectively.
According to research literature, Cefoperazone is very stable against beta - lactamases formed in most gram-negative bacteria. Thanks to that, this active ingredient is evaluated to have strong activity on a broad spectrum of gram-negative bacteria. Basically, Cefoperazone ABR 2g is commonly used against bacteria resistant to other beta-lactam antibiotics.
2. Indications and contraindications of Cefoperazone ABR 2g
2.1. Indications Cefoperazone ABR 2g As mentioned above, Cefoperazone ABR 2g is commonly used in the treatment of serious infections caused by susceptible gram-negative, gram-positive bacteria and bacteria that are resistant to beta-family antibiotics. other -lactams. From here, the drug is indicated for use in cases such as:
Patients with upper and lower respiratory tract infections. The patient has an upper and lower urinary tract infection. People with peritonitis, cholecystitis, cholangitis and some other infections in the abdomen. Sepsis, skin and soft tissue, bone and joint, meningitis ; Pelvic inflammatory disease, endometritis, gonorrhea and other infections of the genital tract. In addition, Cefoperazone ABR 2g is also used in the treatment of postoperative infection prevention for patients undergoing gynecological, cardiovascular, abdominal, orthopedic surgery.
2.2. Contraindications Cefoperazone ABR 2g Do not use Cefoperazone ABR 2g for people with a history of allergy to Cephalosporin antibiotics.
3. Dosage and how to use Cefoperazone ABR 2g
Cefoperazone ABR 2g is used by infusion with the recommended dosage as follows:
Adults: Use at a dose of 2-4g/day, divided into 2 times. For severe infections, use a dose of 8 - 12 = g / day divided into 2 - 3 times, it can be increased to 16 g when necessary. Infants and children: Use at a dose of 50 - 200 = mg/kg/day, divided into 2-4 doses. Particularly, children with meningitis can increase to 300 = mg / kg. Patients with renal impairment: Use a maximum dose of 4g/day.
4. Side effects of Cefoperazone ABR 2g
During the use of the drug, you may encounter some of the following side effects:
Common side effects are urticaria, erythema, fever, leukopenia. An uncommon side effect is hypoprothrombinemia (uncommon and transient). In rare cases, the drug can affect the gastrointestinal system, local reactions, vitamin K deficiency.
5. Be careful when using Cefoperazone ABR 2g
Before taking Cefoperazone, you should inform your doctor about your allergy history, especially if you are allergic to Ceftazidime, Lidocaine or any other drugs. Patients with liver failure or kidney failure, with fibroids should be careful when using the drug. There are no reports on the safety of Cefoperazone ABR 2g in pregnant women. Therefore, this subject should only use the drug when absolutely necessary. Care should be taken when administering the drug to a nursing mother.
6. Drug interactions
The use of Cefoperazone ABR 2g with some other drugs may decrease the absorption of the drug, increase the risk of side effects. Therefore, you need to inform your doctor about any medications you are taking, whether prescription drugs or dietary supplements.
In addition, you need to pay attention to the following issues to avoid drug interactions when using Cefoperazone ABR 2g:
Absolutely do not use alcohol while taking the drug because it can reduce the effectiveness of the drug. Care should be taken when combining Cefoperazone ABR 2g with anticoagulants, thrombolytics, and non-steroidal anti-inflammatory drugs due to the risk of prolonged bleeding. Do not take with drugs containing hydroxylamine hydrochloride, aminophylline, procainamide, pentazocine, proclorperazine, cytochrome C, aprotinin because it can change drug properties. If you need to use it, you should take the 2 medicines about 6 hours apart.
7. Handling when using Cefoperazone ABR 2g overdose or forget dose
In case of drug overdose: If you see unusual signs such as fatigue, vomiting, nausea, dizziness, headache ... the patient should go to the nearest medical address for examination and treatment. timely treatment. If you miss a dose by 1-2 hours, you can take it as usual. However, if you miss a dose by 4-5 hours, skip it and take your next dose at the scheduled time. Absolutely do not double dose or take two doses close to each other will cause adverse effects on health. Above is some information about the use of Cefoperazone ABR 2g. Because this is an antibiotic, the patient should only use it according to the doctor's prescription, absolutely do not arbitrarily use it, there is a risk of extremely dangerous antibiotic resistance.
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