This is an automatically translated article.
Cefmetazol VCP is used to treat and prevent infections caused by anaerobic bacteria. To ensure safety and maximize the effectiveness of treatment, you need to take the medicine exactly as prescribed by your doctor/pharmacist.1. What is Cefmetazol VCP?
Cefmetazol VCP belongs to the group of drugs used to treat parasites, infections, viruses and fungi. The drug is prepared in the form of powder for injection, packing specifications: Box of 1 vial, 10 vials; box of 1 vial + 1 ampoule of distilled water for injection 5ml. Cefmetazol 1g ingredient in Cefmetazol VCP is a Cephalosporin antibiotic, used to treat and prevent infections caused by anaerobic bacteria or mixed infections, uncomplicated gonorrhea.2. Indications to use Cefmetazol VCP
Cefmetazol VCP is indicated in the following cases:
Treatment of infections of the lower respiratory tract, skin and soft tissue, blood, bones, joints and urinary tract caused by susceptible bacteria; Treatment and prevention of infections caused by anaerobic bacteria or mixed infections, especially in the abdomen and pelvic inflammatory disease; Uncomplicated gonorrhea; Prevention of infection during surgery, cesarean section. Do not use Cefmetazol VCP for people with hypersensitivity to penicillin or cephalosporin antibiotics.
3. How to take Cefmetazol VCP
Cefmetazol VCP is injected as the sodium salt. The drug is prescribed slow intravenous injection for 3-5 minutes, intravenous infusion 10-60 minutes and deep intramuscular injection only for sexually transmitted diseases .
Proper dilution for injection:
Cefmetazol VCP solution for injection is distilled water for injection, 5% Dextrose solution and 0.9% sodium chloride solution, Ringer lactate; Cefmetazol VCP must be reconstituted immediately before use, the remaining solution after use should be discarded.
4. Dosage of Cefmetazol VCP
Usual Cefmetazol VCP dose in adults:
Use 0.5 - 1g every 12 hours, intramuscularly or intravenously. If the infection is severe, it can be increased to 3-4g/day, divided into 3-4 times (every 6-8 hours). Reduce the dose of Cefmetazol VCP in patients with renal impairment:
Renal clearance 50 - 90 (mL/min) using a dose of Cefmetazol VCP 0.5 - 1 g every 12 hours; Renal clearance 30 - 49 (mL/min) using a dose of Cefmetazol VCP 0.5 - 1 g every 16 hours; Renal clearance 10 - 29 (mL/min) using a dose of Cefmetazol VCP 0.5 - 1 g every 24 hours; Hemodialysis < 10 (mL/min) using a dose of Cefmetazol VCP 0.5 - 1 g every 48 hours. Dosage of Cefmetazol VCP for surgical prophylaxis in adults:
Use a single dose of Cefmetazol VCP 1 - 2g (IV) 30 - 90 minutes before surgery, repeat (if necessary) after 8 and 16 hours but not more than 4g/ day. Dose of Cefmetazol VCP in cesarean section:
Use a single dose of Cefmetazol VCP 2g (IV) after clamping the umbilical cord. Treatment of uncomplicated gonorrhea in adults:
Intramuscular (IM) single dose of Cefmetazol VCP 1g and oral administration with 1g Probenecid. The dosage of Cefmetazol VCP above is for reference only. The specific dose of Cefmetazol VCP will depend on the condition and the progression of the disease. To get the right dose of Cefmetazol VCP, patients need to consult with their doctor or pharmacist.
5. Use Cefmetazol VCP with caution
Cefmetazol VCP should be used with caution in the following cases:
People with impaired hepatobiliary or renal function; Caution when appointing to people with diseases of the gastrointestinal tract, especially colitis; Caution about dosage and administration in infants and children; Cefmetazol VCP can cause dizziness, so caution should be exercised when driving and operating machinery. Cefmetazol VCP is only used during pregnancy when absolutely necessary, the benefits outweigh the risks to the mother and baby; Cefmetazol VCP is excreted in human milk, so breast-feeding should be discontinued prior to administration.
7. Side effects of Cefmetazol VCP
During the use of Cefmetazol VCP, the patient may experience the following side effects:
Pain at the injection site; Thrombophlebitis ; Rash; Diarrhea; Increased risk of bleeding due to decreased prothrombin and/or platelet dysfunction; Hypersensitivity reactions; Agranulocytosis; Decrease in neutrophils, platelets and prothrombin; Coomb's test false positive; Pseudomembranous colitis; Nausea/vomiting; Toxic to the kidneys. During the course of treatment, if there are any abnormal symptoms suspected of using Cefmetazol VCP, the patient should notify the treating doctor for timely and accurate treatment.
8. Interactions with other drugs
Possible interactions if Cefmetazol VCP is used with the following drugs:
Aminoglycosides; Concomitant use with alcohol causes flushing reactions, profuse sweating, headache and heart palpitations; Using Cefmetazol VCP with diuretics such as furosemide will increase nephrotoxicity; Probenecid reduces renal tubular secretion of Cefmetazol VCP; Concomitant use with colistin increases the risk of tubular damage. The article has provided information about the uses, doses and precautions when using Cefmetazol VCP. To ensure safety for your health and maximize the effectiveness of your treatment, you need to take Cefmetazol VCP exactly as directed by your doctor.
Please dial HOTLINE for more information or register for an appointment HERE. Download MyVinmec app to make appointments faster and to manage your bookings easily.
