This is an automatically translated article.
Cefipron sachet belongs to the group of antibiotics, antivirals, antifungals with the main ingredient cefixime, commonly used to treat otitis media, pharyngitis, sinusitis, tonsillitis, acute bronchitis, pneumonia, neck gonorrhea. uterus. So how does Cefipron sachet work?
1. Uses of the drug Cefipron sachet
Cefipron sachet has the main ingredient cefixim belonging to the third generation cephalosporin antibiotic group with broad antibacterial effect thanks to the bactericidal mechanism by inhibiting bacterial cell wall synthesis. The drug has good activity against gram-negative bacteria, is stable to beta lactamases and achieves bactericidal concentrations in the cerebrospinal fluid. However, it is less effective against gram-positive bacteria than penicillin and first-generation cephalosporins.
The clinical efficacy of cefixime has been demonstrated against many common pathogens such as Streptococcus pyogenes; S. agalactiae, S.pneumoniae; E.coli; Proteus mirabilis; Klebsiella species; Haemophilus influenzae, H.Parainfluenzae (including beta-lactamase-producing strains) Moraxella catarrhalis (including beta-lactamase-producing strains); Neisseria meningitidis; N.gonorrhoeae (including penicillinase-producing strains)...
Regarding the pharmacokinetics of cefixime, it is well absorbed from the gastrointestinal tract and parenteral route with approximately 50% absorption from the gastrointestinal tract, with increased absorption after oral administration. same food. The drug is metabolised by the liver and eliminated mainly by the kidneys. Cefipron sachet is usually indicated in the following cases:
otitis media, pharyngitis, sinusitis, tonsillitis, acute bronchitis, pneumonia. Uncomplicated cervical and urethral gonorrhea. Bladder-urethritis, pyelonephritis - pyelonephritis. Cefipron sachet is contraindicated in patients who are allergic to cephalosporins or any of its ingredients.
2. Dosage of Cefipron sachet
Depending on the subject and the goal of treatment, the dose of Cefipron sachet will be different, specifically as follows:
Adults:
Use 200-400 mg, orally 1-2 times a day. Gonococcal urethritis, a single dose of 400 mg. Patients with renal failure: When the creatinine clearance is about 20ml/min, 200mg/day should be taken. Children:
Use dose of 8mg/kg/day, take 1-2 times per day. Children 6 months - 1 year old: 3.75mg/day. Children 1 - 4 years old: 5mg/day. Children 5-19 years old: 10mg/day. The duration of treatment is 7-10 days.
3. Side effects of the drug Cefipron sachet
In some patients when using Cefipron sachet, side effects may occur such as:
Dizziness, headache. Diarrhea, nausea, vomiting. Flatulence, abdominal pain, indigestion.
4. Be careful when using Cefipron sachet
Some general notes when using Cefipron sachet include:
Caution when using Cefipron sachet for patients with a history of liver failure, severe renal failure. Do not use the drug for children under 6 months of age, pregnant and lactating women. Periodic monitoring of renal function is recommended because renal damage is possible although rare. Cefixime and amikacin when used together may increase the risk of kidney damage. Using cefixime together with BCG might decrease the anti-tumor activity of BCG in the bladder. Chloramphenicol may decrease the effectiveness of cefixime in the treatment of certain infections.
