This is an automatically translated article.
Cantidan drug is prepared in the form of sugar coated tablets with the main ingredient in each tablet is Nystatin 500,000 IU along with excipients including cassava, lactose, PVA, magnesium stearate, talc, sugar, gelatin, TiO2,... So what is Cantidan and how is it used?
1. What is the effect of Cantidan?
Cantidan is an antifungal antibiotic extracted from the culture of Streptomyces noursei, a yellow powder, very slightly soluble in water. Cantidan has an inhibitory or fungicidal effect depending on the concentration of the drug and the sensitivity of the fungus.
Cantidan does not affect the normal bacteria on the body. The most sensitive are yeasts and drugs that work very well on Candida albicans.
Cantidan binds to sterols of the cell membrane of susceptible fungi, so the drug will change the permeability of the fungal membrane. Cantidan is well tolerated even with long-term treatment and does not cause resistance. Cantidan is effective against Candida albicans superinfection in the gastrointestinal tract during antibiotic treatment.
Nystatin in the drug Cantidan is poorly absorbed from the gastrointestinal tract, not absorbed through the skin or mucous membranes when used topically, the drug is mainly eliminated in the feces as unmetabolized.
Cantidan drug is indicated in the following cases:
Prophylaxis and treatment of Candida albicans infection in the oral mucosa and mostly thrush, stomatitis, pharyngitis. Diseases caused by candida in the esophagus, stomach, intestines. Cantidan is contraindicated in patients with a history of hypersensitivity to nystatin. Precautions when using Cantidan:
If a hypersensitivity reaction to the drug occurs, you should stop the drug immediately and take appropriate measures. Cantidan is not used in people with systemic fungal infections because the drug is not absorbed from the gastrointestinal tract.
2. Dosage and how to use Cantidan
Cantidan is used orally, the dose should be according to the doctor's instructions, the reference dose is as follows:
Adults: Use 1 - 2 tablets / time x 3-4 times / day. Children: Use half the adult dose.
3. Cantidan side effects
The drug Cantidan is almost non-toxic and non-sensitizing, the drug is well tolerated at all ages, including infirm children and even with prolonged use. For patients sensitive to candida, when taking oral drugs can cause allergic manifestations due to the sudden destruction of Candida and the release of a lot of candidin, in which case Cantidan should be stopped immediately.
Uncommon side effects of Cantidan include:
Nausea, vomiting Diarrhea Digestive disorders after taking the drug, especially when using the drug with a dose of more than 5 million units a day. External urticaria. Rare side effects of Cantidan include: Local irritation, Stevens - Johnson syndrome ...
If you see any unusual symptoms when using the drug, you need to notify the doctor immediately. doctor or immediately go to the nearest medical facility to receive timely support from medical staff.
4. Interaction of Cantidan with other drugs
When Cantidad is used simultaneously with riboflavin phosphate, it will lose its anti-Candida albicans effect. When using Cantidan orally, it is necessary to avoid using drugs that change intestinal motility, drugs that cover the digestive mucosa because they will interfere with the effect of nystatin in the drug.
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