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Oral infection is a common disease in both children and adults. This recurrent acute and chronic infection has a significant impact on the patient's health and quality of life. Using medication will help quickly overcome the symptoms of the disease. This is also one of the medicinal uses of Cadirogyn. Refer to the article below to learn about the use of Cadirogyn
1. What is Cadirogyn?
Cadirogyn drug is a product of US Pharma USA - Vietnam Co., Ltd. The drug has the main ingredients Spiramycin and Metronidazole along with some other excipients such as: Microcrystallin cellulose, Sodium starch glycolate, Sodium croscarmellose, PEG 6000, Magnesium stearate, Talc, PVP K30, Ethanol 960, Titanium dioxide, HPMC, Purified water .
The drug is prepared in the form of film-coated tablets and packaged in boxes of 10 blisters x 10 tablets.
2. Uses of medicine Cadirogyn
The use of Cadirogyn drug depends mainly on 2 components Spiramycin and Metronidazole.
The effects of Spiramycin include:
This active ingredient has a bacteriostatic effect when reaching serum concentrations and has a bactericidal effect when the drug reaches concentrations in the drug tissue. The drug penetrates and attacks the 50S subunits of the bacterial ribosome and prevents the bacteria from synthesizing proteins. The effects of Metronidazol include:
This is a 5-nitro-imidazole derivative, a broad-spectrum antibiotic that is active against anaerobic bacteria and protozoa (Amoeba, Giardia). Metronidazol is effective in the treatment of infections with Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, Bacteroides, Fusobacterium and other obligate anaerobes. But the drug is not effective against aerobic bacteria. Metronidazole may be prescribed in combination with other medicines to treat stomach ulcers caused by the bacteria Helicobacter pylori. The perfect combination of these two drugs is effective in the treatment of oral infections for Cadirogyn and prevention of dental infections after surgery.
Therefore, Cadirogyn is indicated for prescription in the following cases:
Tooth abscess, gingivitis, inflammation, stomatitis, perimandibular cellulitis, parotid gland inflammation, salivary gland infection Prevention Oral infection after surgery. On the other hand, this drug is not prescribed in the following cases:
Patients with hypersensitivity to Spiramycin and Metronidazole or any of its ingredients. Patients with a history of hypersensitivity to erythromycin and other nitro-imidazole derivatives.
3. Dosage of Cadirogyn
To use the drug safely, the patient needs to carefully read the instructions for use or follow the instructions of the doctor. Cadirogyn drug is used orally, take the tablet whole, do not chew or crush the tablet.
The dose of Cadirogyn depends on the condition of the patient that the doctor will prescribe. Below is the reference dose for adults and children:
For adults, the dose is 4-6 tablets/day, divided into 2-3 times. For children from 5 to 10 years old, the dose is 2 tablets per day. For children from 10 to 15 years old, the recommended dose is 3 tablets per day. In the event of a missed dose, the patient should take it as soon as he remembers. If it is almost time for the next dose, take the next dose, do not arbitrarily double the dose to make up for the missed dose.
In case of overdose, the patient may experience some symptoms such as nausea, ataxia, jerks, peripheral neuritis,...and some other manifestations. At this time, the patient needs to be taken to the hospital for a doctor to examine and take measures to remove the medicinal properties in the patient's body.
4. Side effects Cadirogyn
Some side effects patients may experience during the use of Cadirogyn include: stomach pain, nausea, diarrhea, rash, stomatitis, dizziness, red-brown urine, ..
The above are not all side effects of Cadirogyn. If you experience any unusual symptoms suspected of being caused by this drug, you should notify your doctor for treatment.
5. Cadirogyn drug interactions
Drug interactions between one or more drugs in combination can cause unwanted side effects or reduce the effectiveness of the drug. The drug Cadirogyn may interact when used with the following drugs:
Disulfiram: can lead to paranoia and psychosis. Anticoagulants (warfarin) Metronidazole may increase serum lithium levels, immobilize spirochetes, and thus may falsify the results of Nelson's test.
6. Notes when using Cadirogyn
Here are some precautions for patients using Cadirogyn:
Despite animal studies, Cadirogyn has no teratogenic or negative effects on the fetus. However, women who are in pregnancy should be cautious and consult a doctor before having the need to use this drug. The two main ingredients of this medicine can pass into breast milk, so women who are breastfeeding should not take this medicine. It can be used by people who drive or operate machinery, but caution should be exercised as side effects such as dizziness affect concentration at work. Patients with liver dysfunction should consult a doctor before taking the drug. Long-term or high-dose metronidazole can sometimes cause peripheral neuropathy, transient epileptic seizures, and leukopenia and should be used with caution. During the use of the drug should not drink alcohol because the metronidazole component in the drug can cause a disulfiram-like reaction.
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